Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 264
Breast cancer 134
Plasma cell myeloma 129
Neoplasm 128
Neoplasm malignant 106
Acute myeloid leukaemia 106
Prostate cancer 92
Colitis ulcerative 89
Obesity 86
Colorectal cancer metastatic 85
Colorectal cancer 78
Ovarian cancer 76
Hepatocellular carcinoma 76
Crohn’s disease 73
Dementia Alzheimer’s type 73
Malignant melanoma 73
Breast cancer metastatic 70
Dermatitis atopic 67
Type 2 diabetes mellitus 66
Chronic lymphocytic leukaemia 64
Triple negative breast cancer 64
HIV infection 63
Rheumatoid arthritis 63
Non-small cell lung cancer metastatic 63
Asthma 61
Squamous cell carcinoma of head and neck 61
Osteoarthritis 57
Hormone receptor positive HER2 negative breast cancer 54
Chronic kidney disease 54
Pancreatic carcinoma 52
Renal transplant 51
Systemic lupus erythematosus 48
Multiple sclerosis 47
Hormone-refractory prostate cancer 47
Ischaemic stroke 46
Parkinson’s disease 46
Non-small cell lung cancer stage IV 45
Gastric cancer 44
Chronic obstructive pulmonary disease 44
Atrial fibrillation 43
Bladder cancer 43
Diffuse large B-cell lymphoma 43
Psoriasis 43
Endometrial cancer 41
Oesophageal adenocarcinoma 41
Prostate cancer metastatic 40
Myelodysplastic syndrome 40
Cardiac failure 40
Major depression 39
Psoriatic arthropathy 39
Migraine 38
Glioblastoma 38
Transitional cell carcinoma 38
Type 1 diabetes mellitus 37
Overweight 37
Myasthenia gravis 35
Cholangiocarcinoma 35
Acute lymphocytic leukaemia 35
Hidradenitis 34
COVID-19 34
Schizophrenia 33
Hormone receptor positive breast cancer 33
Plasma cell myeloma refractory 33
HER2 positive breast cancer 33
Systemic scleroderma 32
Head and neck cancer 32
Renal cell carcinoma 32
Adenocarcinoma pancreas 31
Cervix carcinoma 31
Coronary artery disease 30
Non-small cell lung cancer stage III 30
Pulmonary arterial hypertension 30
Depression 30
Rectal cancer 30
Follicular lymphoma 30
Oesophageal carcinoma 29
Pancreatic carcinoma metastatic 29
Metastatic malignant melanoma 29
Bladder transitional cell carcinoma 29
Small cell lung cancer extensive stage 27
Adenocarcinoma gastric 26
Amyotrophic lateral sclerosis 25
Pneumonia 25
Duchenne muscular dystrophy 25
B-cell lymphoma 25
Myelofibrosis 25
Interstitial lung disease 25
Soft tissue sarcoma 25
Endocrine ophthalmopathy 25
Fallopian tube cancer 24
Non-small cell lung cancer stage IIIB 24
Procedural pain 24
Colon cancer 24
Chronic myeloid leukaemia 24
Acute myocardial infarction 24
Lung neoplasm malignant 24
B-cell small lymphocytic lymphoma 24
Sepsis 24
Small cell lung cancer 23
Idiopathic pulmonary fibrosis 23

Diseases starting with u

  • 1

    Ulcerative keratitis

    Ulcerative keratitis is a serious inflammatory eye condition that causes painful sores and tissue breakdown in the cornea, requiring immediate medical attention to prevent vision loss and, in some cases, life-threatening complications.

  • 1

    Underweight

    Being underweight means your body weight falls below the healthy range needed for your body to function properly. This can lead to various health problems, from weakened bones to fertility issues, and may require medical attention to address underlying causes and restore healthy weight.

  • 1

    Undifferentiated sarcoma

    Undifferentiated sarcoma is a rare type of cancer that develops in the body’s connective tissues, often affecting the arms, legs, or abdomen. This aggressive disease requires prompt diagnosis and a combination of treatments to give patients the best chance of recovery.

  • 1

    Univentricular heart

    Univentricular heart is a group of serious heart conditions present at birth where only one of the heart’s two pumping chambers can work properly to support the body’s blood circulation.

  • 2

    Upper limb fracture

    An upper limb fracture occurs when one of the bones in your arm breaks, from your shoulder down to your hand and fingers. These breaks can range from small cracks to bones broken into multiple pieces, and while they’re often caused by serious accidents, proper treatment can help restore full function of your arm.

  • 1

    Upper respiratory tract infection

    Upper respiratory tract infections are among the most common illnesses worldwide, affecting millions of people every year. While these infections can be uncomfortable and disrupt daily life, most are caused by viruses and resolve on their own with proper care and rest.

  • 2

    Urea cycle disorder

    Urea cycle disorder is a group of rare genetic conditions that prevent the body from removing toxic ammonia from the blood. When ammonia builds up, it can cause serious brain damage and affect organ function, making these disorders life-threatening without proper treatment.

  • 1

    Ureteric cancer

    Ureteric cancer is a rare type of cancer that develops in the ureters, the tubes that carry urine from the kidneys to the bladder. Though uncommon, it most often affects older adults and is closely linked to bladder cancer, requiring careful monitoring and specialized treatment.

  • 1

    Urethral stenosis

    Urethral stenosis, also called urethral stricture, is a narrowing of the tube that carries urine out of your body. This narrowing makes it difficult and sometimes painful to urinate, and without treatment, it can lead to serious complications affecting your bladder and kidneys.

  • 2

    Urethral valves

    Urethral valves are a birth defect affecting only boys, where extra flaps of tissue block the tube that carries urine out of the body, potentially causing serious damage to the bladder and kidneys if left untreated.

  • 5

    Urinary incontinence

    Urinary incontinence, the involuntary loss of bladder control, affects millions of people worldwide, yet many suffer in silence due to embarrassment. While it becomes more common with age, it is not an inevitable part of getting older, and effective treatments are available to help you regain control and improve your quality of life.

  • 15

    Urinary tract infection

    Urinary tract infections are among the most common bacterial infections people experience, affecting millions each year. While these infections can be uncomfortable and disruptive, understanding the symptoms, causes, and treatment options can help you recognize when to seek care and how to reduce your risk.

  • 2

    Urticaria

    Urticaria, commonly known as hives, affects about 20 percent of people at some time during their lives, causing intensely itchy, raised welts that appear suddenly and can last from minutes to months or even years.

  • 1

    Urticaria cholinergic

    Cholinergic urticaria causes small, itchy bumps to appear on your skin when your body temperature rises and you start to sweat, triggered by activities like exercise, hot showers, stress, or even eating spicy foods.

  • 5

    Urticaria chronic

    Chronic urticaria is a condition where itchy, raised welts appear on your skin at least twice per week for more than six weeks. For many people, the cause remains unknown, but treatments can help control symptoms and improve quality of life.

  • 2

    Usher’s syndrome

    Usher’s syndrome is a rare genetic condition that affects both hearing and vision, and is the most common cause of combined deafness and blindness.

  • 0

    Uterine cancer

    Uterine cancer is a disease in which cells in the uterus grow out of control. It is the most common cancer affecting the female reproductive system, and while it can be serious, many cases can be cured when detected early.

  • 2

    Uterine leiomyoma

    Uterine leiomyoma, commonly known as fibroids, are noncancerous growths that develop in or on the uterus and affect millions of women during their reproductive years. While many women experience no symptoms, others face significant challenges including heavy bleeding, pain, and complications affecting their quality of life.

  • 2

    Uterine leiomyosarcoma

    Uterine leiomyosarcoma is a rare and aggressive cancer that develops in the muscle wall of the uterus, accounting for only 2% to 5% of all uterine cancers. Despite often being discovered in early stages, this challenging disease requires specialized treatment and long-term monitoring.

  • 13

    Uveal melanoma

    Uveal melanoma is the most common type of eye cancer in adults, yet it remains a rare disease affecting only about 5 people per million each year. Though small tumors can often be treated while preserving vision, this cancer carries a significant risk of spreading to other organs, making early detection and expert care essential.

  • 7

    Uveitis

    Uveitis is inflammation inside the eye that can cause pain, redness, and vision problems. While it affects millions of people worldwide each year, early diagnosis and treatment can prevent serious complications, including permanent vision loss.