Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease trials
Non-small cell lung cancer 228
Breast cancer 94
Obesity 86
Prostate cancer 73
Colorectal cancer 69
Ovarian cancer 66
Non-small cell lung cancer metastatic 66
Crohn’s disease 61
Type 2 diabetes mellitus 54
Rheumatoid arthritis 54
Triple negative breast cancer 52
Hormone receptor positive HER2 negative breast cancer 52
Asthma 51
Acute myeloid leukaemia 50
Squamous cell carcinoma of head and neck 50
Chronic kidney disease 49
Neoplasm 48
Colorectal cancer metastatic 47
Hepatocellular carcinoma 47
Systemic lupus erythematosus 40
Colitis ulcerative 40
Multiple sclerosis 39
Overweight 39
Dementia Alzheimer’s type 39
Gastric cancer 38
Myelodysplastic syndrome 37
Parkinson’s disease 37
HER2 positive breast cancer 37
Glioblastoma 37
Atrial fibrillation 34
Bladder cancer 34
Chronic obstructive pulmonary disease 33
Ischaemic stroke 33
Prostate cancer metastatic 33
Myasthenia gravis 32
Renal transplant 31
Type 1 diabetes mellitus 31
Head and neck cancer 31
Endometrial cancer 31
Malignant melanoma 31
Non-small cell lung cancer stage IV 31
Diffuse large B-cell lymphoma 31
Breast cancer metastatic 31
HIV infection 30
Dermatitis atopic 28
Cholangiocarcinoma 28
Coronary artery disease 28
Plasma cell myeloma 28
Pulmonary arterial hypertension 28
Neoplasm malignant 27
Rectal cancer 27
Renal cell carcinoma 26
Pancreatic carcinoma 26
Schizophrenia 26
Duchenne muscular dystrophy 25
Non-small cell lung cancer stage III 25
Follicular lymphoma 25
COVID-19 25
Migraine 24
Hormone receptor positive breast cancer 24
Idiopathic pulmonary fibrosis 24
Non-small cell lung cancer stage IIIB 24
Sepsis 24
Chronic lymphocytic leukaemia 24
Soft tissue sarcoma 24
Mantle cell lymphoma 23
Small cell lung cancer extensive stage 23
Colon cancer 23
Fallopian tube cancer 23
Influenza 22
Small cell lung cancer 21
Interstitial lung disease 21
Acute myocardial infarction 21
Oesophageal adenocarcinoma 21
Amyotrophic lateral sclerosis 21
Chronic rhinosinusitis with nasal polyps 20
Cystic fibrosis 20
Glioma 20
Myelofibrosis 19
Neuroblastoma 19
B-cell lymphoma 19
Sickle cell disease 19
Major depression 19
Procedural pain 19
Axial spondyloarthritis 18
Osteoarthritis 18
Breast cancer female 17
Critical illness 17
Acute kidney injury 17
Hereditary angioedema 17
Relapsing-remitting multiple sclerosis 16
Acute coronary syndrome 16
IgA nephropathy 16
Psoriasis 16
Gastrooesophageal cancer 16
Ewing’s sarcoma 16
Cardiac failure 16
Vitiligo 16
Transitional cell carcinoma 15
Giant cell arteritis 15

Diseases starting with k

  • 1

    K-ras gene mutation

    A mutation in the KRAS gene is one of the most frequently found genetic changes in cancer, affecting how cells grow and divide. Understanding this mutation can help guide treatment decisions for many patients with cancer.

  • 2

    Kaposi’s sarcoma

    Kaposi’s sarcoma is a type of cancer that forms in the lining of blood and lymph vessels, causing distinctive colored skin lesions that can also affect internal organs in more severe cases.

  • 1

    Kawasaki’s disease

    Kawasaki’s disease is a rare condition that causes inflammation in blood vessels throughout the body, mainly affecting young children. While it can seem frightening with its high fever and visible symptoms, early treatment can prevent serious complications and most children recover fully.

  • 1

    KBG syndrome

    KBG syndrome is a rare genetic disorder that affects multiple body systems, characterized by distinctive facial features, unusually large front teeth, short stature, skeletal abnormalities, and developmental delays. Named after the initials of the first families diagnosed, this condition shows wide variation in how it affects individuals, even within the same family.

  • 1

    Kearns-Sayre syndrome

    Kearns-Sayre syndrome is a rare condition that mainly affects the eyes, heart, and muscles, caused by problems in the tiny energy-producing structures within body cells. Most people develop symptoms before age 20, and while there is no cure, early diagnosis and supportive care can help manage the condition and improve quality of life.

  • 0

    Keratinising squamous cell carcinoma of nasopharynx

    Keratinising squamous cell carcinoma of the nasopharynx is a distinct type of throat cancer that forms in the upper part of the throat behind the nose, where cancer cells are covered with a protein called keratin.

  • 0

    Keratosis follicular

    Keratosis pilaris is a common and harmless skin condition that affects millions of people worldwide, causing small, rough bumps that many describe as “chicken skin” or “gooseflesh.”

  • 9

    Kidney transplant rejection

    Kidney transplant rejection happens when your body’s immune system recognizes your new kidney as foreign and tries to attack it. While this can sound frightening, understanding the signs and knowing that most rejection episodes can be successfully treated can help you protect your new kidney.

  • 1

    Klinefelter’s syndrome

    Klinefelter’s syndrome is a common genetic condition affecting males who are born with at least one extra X chromosome, leading to a wide range of physical and developmental differences that many may not even realize they have.

  • 4

    Knee arthroplasty

    Knee arthroplasty is one of the most successful surgeries performed today, helping people with severe knee pain and limited mobility return to their daily activities and enjoy life again.

  • 1

    Krabbe’s disease

    Krabbe’s disease is a rare, inherited condition that progressively damages the protective covering of nerve cells in the brain and nervous system, leading to severe neurological problems that worsen over time and usually result in death, most commonly affecting babies in their first year of life.