Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 238
Breast cancer 131
Neoplasm 124
Plasma cell myeloma 122
Acute myeloid leukaemia 102
Neoplasm malignant 91
Prostate cancer 89
Colitis ulcerative 87
Obesity 81
Colorectal cancer metastatic 80
Crohn’s disease 76
Dementia Alzheimer’s type 75
Ovarian cancer 71
Type 2 diabetes mellitus 71
Colorectal cancer 69
Dermatitis atopic 66
Malignant melanoma 65
Breast cancer metastatic 65
Hepatocellular carcinoma 63
Triple negative breast cancer 62
Chronic lymphocytic leukaemia 60
Asthma 60
Non-small cell lung cancer metastatic 59
Squamous cell carcinoma of head and neck 58
Rheumatoid arthritis 58
HIV infection 57
Hormone receptor positive HER2 negative breast cancer 55
Osteoarthritis 55
Renal transplant 50
Pancreatic carcinoma 49
Chronic kidney disease 49
Ischaemic stroke 45
Parkinson’s disease 44
Atrial fibrillation 44
Systemic lupus erythematosus 43
Multiple sclerosis 42
Gastric cancer 42
Oesophageal adenocarcinoma 40
Hormone-refractory prostate cancer 40
Bladder cancer 40
Chronic obstructive pulmonary disease 40
Psoriasis 40
Non-small cell lung cancer stage IV 40
Migraine 39
Major depression 38
Endometrial cancer 38
Psoriatic arthropathy 37
Overweight 36
Myelodysplastic syndrome 36
Glioblastoma 36
Transitional cell carcinoma 36
Cardiac failure 35
Diffuse large B-cell lymphoma 35
Hormone receptor positive breast cancer 33
Systemic scleroderma 33
Schizophrenia 32
Type 1 diabetes mellitus 32
COVID-19 32
Cholangiocarcinoma 32
Prostate cancer metastatic 31
Head and neck cancer 31
Hidradenitis 31
HER2 positive breast cancer 30
Adenocarcinoma pancreas 30
Myasthenia gravis 30
Cervix carcinoma 29
Coronary artery disease 29
Acute lymphocytic leukaemia 29
Renal cell carcinoma 29
Rectal cancer 29
Pulmonary arterial hypertension 28
Follicular lymphoma 28
Plasma cell myeloma refractory 28
Pancreatic carcinoma metastatic 27
Oesophageal carcinoma 27
Depression 27
Bladder transitional cell carcinoma 27
Adenocarcinoma gastric 26
Pneumonia 26
Procedural pain 25
Interstitial lung disease 25
Metastatic malignant melanoma 25
B-cell lymphoma 25
Acute myocardial infarction 25
Idiopathic pulmonary fibrosis 24
Myelofibrosis 24
Non-small cell lung cancer stage III 24
Colon cancer 24
Amyotrophic lateral sclerosis 24
Non-small cell lung cancer stage IIIB 24
Fallopian tube cancer 23
Small cell lung cancer 23
Breast cancer female 23
Sjogren’s syndrome 23
B-cell small lymphocytic lymphoma 22
Soft tissue sarcoma 22
Cardiac amyloidosis 22
Lung neoplasm malignant 22
Sepsis 22
Small cell lung cancer extensive stage 22

Diseases starting with k

  • 3

    K-ras gene mutation

    A mutation in the KRAS gene is one of the most frequently found genetic changes in cancer, affecting how cells grow and divide. Understanding this mutation can help guide treatment decisions for many patients with cancer.

  • 2

    Kaposi’s sarcoma

    Kaposi’s sarcoma is a type of cancer that forms in the lining of blood and lymph vessels, causing distinctive colored skin lesions that can also affect internal organs in more severe cases.

  • 1

    Kawasaki’s disease

    Kawasaki’s disease is a rare condition that causes inflammation in blood vessels throughout the body, mainly affecting young children. While it can seem frightening with its high fever and visible symptoms, early treatment can prevent serious complications and most children recover fully.

  • 1

    KBG syndrome

    KBG syndrome is a rare genetic disorder that affects multiple body systems, characterized by distinctive facial features, unusually large front teeth, short stature, skeletal abnormalities, and developmental delays. Named after the initials of the first families diagnosed, this condition shows wide variation in how it affects individuals, even within the same family.

  • 1

    Kearns-Sayre syndrome

    Kearns-Sayre syndrome is a rare condition that mainly affects the eyes, heart, and muscles, caused by problems in the tiny energy-producing structures within body cells. Most people develop symptoms before age 20, and while there is no cure, early diagnosis and supportive care can help manage the condition and improve quality of life.

  • 1

    Keratinising squamous cell carcinoma of nasopharynx

    Keratinising squamous cell carcinoma of the nasopharynx is a distinct type of throat cancer that forms in the upper part of the throat behind the nose, where cancer cells are covered with a protein called keratin.

  • 1

    Keratosis follicular

    Keratosis pilaris is a common and harmless skin condition that affects millions of people worldwide, causing small, rough bumps that many describe as “chicken skin” or “gooseflesh.”

  • 8

    Kidney transplant rejection

    Kidney transplant rejection happens when your body’s immune system recognizes your new kidney as foreign and tries to attack it. While this can sound frightening, understanding the signs and knowing that most rejection episodes can be successfully treated can help you protect your new kidney.

  • 1

    Klinefelter’s syndrome

    Klinefelter’s syndrome is a common genetic condition affecting males who are born with at least one extra X chromosome, leading to a wide range of physical and developmental differences that many may not even realize they have.

  • 4

    Knee arthroplasty

    Knee arthroplasty is one of the most successful surgeries performed today, helping people with severe knee pain and limited mobility return to their daily activities and enjoy life again.

  • 1

    Krabbe’s disease

    Krabbe’s disease is a rare, inherited condition that progressively damages the protective covering of nerve cells in the brain and nervous system, leading to severe neurological problems that worsen over time and usually result in death, most commonly affecting babies in their first year of life.