Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 264
Breast cancer 134
Plasma cell myeloma 129
Neoplasm 128
Neoplasm malignant 106
Acute myeloid leukaemia 106
Prostate cancer 92
Colitis ulcerative 89
Obesity 86
Colorectal cancer metastatic 85
Colorectal cancer 78
Ovarian cancer 76
Hepatocellular carcinoma 76
Crohn’s disease 73
Dementia Alzheimer’s type 73
Malignant melanoma 73
Breast cancer metastatic 70
Dermatitis atopic 67
Type 2 diabetes mellitus 66
Chronic lymphocytic leukaemia 64
Triple negative breast cancer 64
HIV infection 63
Rheumatoid arthritis 63
Non-small cell lung cancer metastatic 63
Asthma 61
Squamous cell carcinoma of head and neck 61
Osteoarthritis 57
Hormone receptor positive HER2 negative breast cancer 54
Chronic kidney disease 54
Pancreatic carcinoma 52
Renal transplant 51
Systemic lupus erythematosus 48
Multiple sclerosis 47
Hormone-refractory prostate cancer 47
Ischaemic stroke 46
Parkinson’s disease 46
Non-small cell lung cancer stage IV 45
Gastric cancer 44
Chronic obstructive pulmonary disease 44
Atrial fibrillation 43
Bladder cancer 43
Diffuse large B-cell lymphoma 43
Psoriasis 43
Endometrial cancer 41
Oesophageal adenocarcinoma 41
Prostate cancer metastatic 40
Myelodysplastic syndrome 40
Cardiac failure 40
Major depression 39
Psoriatic arthropathy 39
Migraine 38
Glioblastoma 38
Transitional cell carcinoma 38
Type 1 diabetes mellitus 37
Overweight 37
Myasthenia gravis 35
Cholangiocarcinoma 35
Acute lymphocytic leukaemia 35
Hidradenitis 34
COVID-19 34
Schizophrenia 33
Hormone receptor positive breast cancer 33
Plasma cell myeloma refractory 33
HER2 positive breast cancer 33
Systemic scleroderma 32
Head and neck cancer 32
Renal cell carcinoma 32
Adenocarcinoma pancreas 31
Cervix carcinoma 31
Coronary artery disease 30
Non-small cell lung cancer stage III 30
Pulmonary arterial hypertension 30
Depression 30
Rectal cancer 30
Follicular lymphoma 30
Oesophageal carcinoma 29
Pancreatic carcinoma metastatic 29
Metastatic malignant melanoma 29
Bladder transitional cell carcinoma 29
Small cell lung cancer extensive stage 27
Adenocarcinoma gastric 26
Amyotrophic lateral sclerosis 25
Pneumonia 25
Duchenne muscular dystrophy 25
B-cell lymphoma 25
Myelofibrosis 25
Interstitial lung disease 25
Soft tissue sarcoma 25
Endocrine ophthalmopathy 25
Fallopian tube cancer 24
Non-small cell lung cancer stage IIIB 24
Procedural pain 24
Colon cancer 24
Chronic myeloid leukaemia 24
Acute myocardial infarction 24
Lung neoplasm malignant 24
B-cell small lymphocytic lymphoma 24
Sepsis 24
Small cell lung cancer 23
Idiopathic pulmonary fibrosis 23

Diseases starting with k

  • 9

    K-ras gene mutation

    A mutation in the KRAS gene is one of the most frequently found genetic changes in cancer, affecting how cells grow and divide. Understanding this mutation can help guide treatment decisions for many patients with cancer.

  • 2

    Kaposi’s sarcoma

    Kaposi’s sarcoma is a type of cancer that forms in the lining of blood and lymph vessels, causing distinctive colored skin lesions that can also affect internal organs in more severe cases.

  • 1

    Kawasaki’s disease

    Kawasaki’s disease is a rare condition that causes inflammation in blood vessels throughout the body, mainly affecting young children. While it can seem frightening with its high fever and visible symptoms, early treatment can prevent serious complications and most children recover fully.

  • 1

    KBG syndrome

    KBG syndrome is a rare genetic disorder that affects multiple body systems, characterized by distinctive facial features, unusually large front teeth, short stature, skeletal abnormalities, and developmental delays. Named after the initials of the first families diagnosed, this condition shows wide variation in how it affects individuals, even within the same family.

  • 1

    Kearns-Sayre syndrome

    Kearns-Sayre syndrome is a rare condition that mainly affects the eyes, heart, and muscles, caused by problems in the tiny energy-producing structures within body cells. Most people develop symptoms before age 20, and while there is no cure, early diagnosis and supportive care can help manage the condition and improve quality of life.

  • 1

    Keratinising squamous cell carcinoma of nasopharynx

    Keratinising squamous cell carcinoma of the nasopharynx is a distinct type of throat cancer that forms in the upper part of the throat behind the nose, where cancer cells are covered with a protein called keratin.

  • 1

    Keratosis follicular

    Keratosis pilaris is a common and harmless skin condition that affects millions of people worldwide, causing small, rough bumps that many describe as “chicken skin” or “gooseflesh.”

  • 8

    Kidney transplant rejection

    Kidney transplant rejection happens when your body’s immune system recognizes your new kidney as foreign and tries to attack it. While this can sound frightening, understanding the signs and knowing that most rejection episodes can be successfully treated can help you protect your new kidney.

  • 1

    Klinefelter’s syndrome

    Klinefelter’s syndrome is a common genetic condition affecting males who are born with at least one extra X chromosome, leading to a wide range of physical and developmental differences that many may not even realize they have.

  • 4

    Knee arthroplasty

    Knee arthroplasty is one of the most successful surgeries performed today, helping people with severe knee pain and limited mobility return to their daily activities and enjoy life again.

  • 1

    Krabbe’s disease

    Krabbe’s disease is a rare, inherited condition that progressively damages the protective covering of nerve cells in the brain and nervous system, leading to severe neurological problems that worsen over time and usually result in death, most commonly affecting babies in their first year of life.