Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 228
Breast cancer 125
Neoplasm 124
Plasma cell myeloma 120
Acute myeloid leukaemia 107
Neoplasm malignant 93
Obesity 87
Prostate cancer 84
Colitis ulcerative 84
Colorectal cancer metastatic 83
Ovarian cancer 71
Colorectal cancer 70
Type 2 diabetes mellitus 68
Dementia Alzheimer’s type 68
Crohn’s disease 67
Dermatitis atopic 62
Hepatocellular carcinoma 62
HIV infection 60
Triple negative breast cancer 60
Malignant melanoma 60
Breast cancer metastatic 60
Non-small cell lung cancer metastatic 57
Rheumatoid arthritis 56
Asthma 54
Osteoarthritis 54
Hormone receptor positive HER2 negative breast cancer 53
Renal transplant 53
Chronic lymphocytic leukaemia 51
Squamous cell carcinoma of head and neck 50
Chronic kidney disease 49
Pancreatic carcinoma 48
Atrial fibrillation 46
Systemic lupus erythematosus 45
Parkinson’s disease 44
Ischaemic stroke 44
Oesophageal adenocarcinoma 43
Gastric cancer 43
Psoriasis 43
Multiple sclerosis 43
Hormone-refractory prostate cancer 41
Overweight 40
Bladder cancer 38
Diffuse large B-cell lymphoma 37
Endometrial cancer 37
Non-small cell lung cancer stage IV 37
Cardiac failure 36
Migraine 36
Myelodysplastic syndrome 36
Glioblastoma 35
Major depression 35
Chronic obstructive pulmonary disease 34
Transitional cell carcinoma 34
Hidradenitis 34
COVID-19 32
Hormone receptor positive breast cancer 32
Psoriatic arthropathy 32
Acute lymphocytic leukaemia 31
Cholangiocarcinoma 31
Systemic scleroderma 31
Prostate cancer metastatic 31
Type 1 diabetes mellitus 31
Bladder transitional cell carcinoma 30
Myasthenia gravis 30
Plasma cell myeloma refractory 29
HER2 positive breast cancer 29
Schizophrenia 29
Head and neck cancer 28
Oesophageal carcinoma 28
Coronary artery disease 28
Adenocarcinoma pancreas 27
Cervix carcinoma 27
Pneumonia 27
Adenocarcinoma gastric 26
Renal cell carcinoma 26
Idiopathic pulmonary fibrosis 26
Depression 26
Rectal cancer 26
Small cell lung cancer extensive stage 26
Non-small cell lung cancer stage III 26
Procedural pain 26
Follicular lymphoma 26
Interstitial lung disease 25
Metastatic malignant melanoma 25
B-cell lymphoma 24
Pancreatic carcinoma metastatic 24
Myelofibrosis 23
Pulmonary arterial hypertension 23
Sepsis 23
Fallopian tube cancer 23
Colon cancer 23
Sjogren’s syndrome 22
Non-small cell lung cancer stage IIIB 22
Soft tissue sarcoma 22
Hepatic cirrhosis 21
Endocrine ophthalmopathy 21
Breast cancer female 21
Lung neoplasm malignant 21
Mantle cell lymphoma 21
Acute myocardial infarction 21
Neovascular age-related macular degeneration 20

Diseases starting with k

  • 4

    K-ras gene mutation

    A mutation in the KRAS gene is one of the most frequently found genetic changes in cancer, affecting how cells grow and divide. Understanding this mutation can help guide treatment decisions for many patients with cancer.

  • 2

    Kaposi’s sarcoma

    Kaposi’s sarcoma is a type of cancer that forms in the lining of blood and lymph vessels, causing distinctive colored skin lesions that can also affect internal organs in more severe cases.

  • 1

    Kawasaki’s disease

    Kawasaki’s disease is a rare condition that causes inflammation in blood vessels throughout the body, mainly affecting young children. While it can seem frightening with its high fever and visible symptoms, early treatment can prevent serious complications and most children recover fully.

  • 1

    KBG syndrome

    KBG syndrome is a rare genetic disorder that affects multiple body systems, characterized by distinctive facial features, unusually large front teeth, short stature, skeletal abnormalities, and developmental delays. Named after the initials of the first families diagnosed, this condition shows wide variation in how it affects individuals, even within the same family.

  • 1

    Kearns-Sayre syndrome

    Kearns-Sayre syndrome is a rare condition that mainly affects the eyes, heart, and muscles, caused by problems in the tiny energy-producing structures within body cells. Most people develop symptoms before age 20, and while there is no cure, early diagnosis and supportive care can help manage the condition and improve quality of life.

  • 1

    Keratinising squamous cell carcinoma of nasopharynx

    Keratinising squamous cell carcinoma of the nasopharynx is a distinct type of throat cancer that forms in the upper part of the throat behind the nose, where cancer cells are covered with a protein called keratin.

  • 0

    Keratosis follicular

    Keratosis pilaris is a common and harmless skin condition that affects millions of people worldwide, causing small, rough bumps that many describe as “chicken skin” or “gooseflesh.”

  • 8

    Kidney transplant rejection

    Kidney transplant rejection happens when your body’s immune system recognizes your new kidney as foreign and tries to attack it. While this can sound frightening, understanding the signs and knowing that most rejection episodes can be successfully treated can help you protect your new kidney.

  • 1

    Klinefelter’s syndrome

    Klinefelter’s syndrome is a common genetic condition affecting males who are born with at least one extra X chromosome, leading to a wide range of physical and developmental differences that many may not even realize they have.

  • 4

    Knee arthroplasty

    Knee arthroplasty is one of the most successful surgeries performed today, helping people with severe knee pain and limited mobility return to their daily activities and enjoy life again.

  • 1

    Krabbe’s disease

    Krabbe’s disease is a rare, inherited condition that progressively damages the protective covering of nerve cells in the brain and nervous system, leading to severe neurological problems that worsen over time and usually result in death, most commonly affecting babies in their first year of life.