Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 257
Breast cancer 130
Neoplasm 124
Plasma cell myeloma 124
Acute myeloid leukaemia 103
Neoplasm malignant 102
Colitis ulcerative 93
Prostate cancer 91
Colorectal cancer metastatic 84
Obesity 84
Colorectal cancer 76
Crohn’s disease 76
Ovarian cancer 76
Dementia Alzheimer’s type 74
Hepatocellular carcinoma 73
Malignant melanoma 69
Breast cancer metastatic 68
Type 2 diabetes mellitus 67
Dermatitis atopic 65
Triple negative breast cancer 62
Chronic lymphocytic leukaemia 62
Squamous cell carcinoma of head and neck 60
HIV infection 58
Rheumatoid arthritis 58
Asthma 57
Non-small cell lung cancer metastatic 57
Osteoarthritis 56
Hormone receptor positive HER2 negative breast cancer 54
Pancreatic carcinoma 51
Renal transplant 51
Chronic kidney disease 50
Multiple sclerosis 48
Ischaemic stroke 46
Parkinson’s disease 46
Chronic obstructive pulmonary disease 46
Systemic lupus erythematosus 46
Hormone-refractory prostate cancer 46
Atrial fibrillation 44
Bladder cancer 42
Gastric cancer 42
Non-small cell lung cancer stage IV 41
Diffuse large B-cell lymphoma 41
Psoriasis 41
Migraine 41
Oesophageal adenocarcinoma 40
Major depression 38
Myelodysplastic syndrome 38
Transitional cell carcinoma 38
Glioblastoma 38
Psoriatic arthropathy 38
Prostate cancer metastatic 37
Endometrial cancer 37
Overweight 36
Cardiac failure 35
Acute lymphocytic leukaemia 35
Cholangiocarcinoma 35
COVID-19 34
Hormone receptor positive breast cancer 34
Systemic scleroderma 34
Hidradenitis 33
HER2 positive breast cancer 33
Type 1 diabetes mellitus 33
Schizophrenia 32
Myasthenia gravis 32
Renal cell carcinoma 32
Head and neck cancer 32
Plasma cell myeloma refractory 32
Coronary artery disease 31
Adenocarcinoma pancreas 31
Rectal cancer 30
Cervix carcinoma 30
Follicular lymphoma 30
Pulmonary arterial hypertension 29
Pancreatic carcinoma metastatic 29
Depression 29
Idiopathic pulmonary fibrosis 28
Oesophageal carcinoma 27
Bladder transitional cell carcinoma 27
Small cell lung cancer extensive stage 27
Metastatic malignant melanoma 26
Interstitial lung disease 26
Non-small cell lung cancer stage III 25
B-cell lymphoma 25
Fallopian tube cancer 25
Pneumonia 25
Lung neoplasm malignant 25
Adenocarcinoma gastric 25
Procedural pain 24
Soft tissue sarcoma 24
Myelofibrosis 24
Small cell lung cancer 24
Amyotrophic lateral sclerosis 24
Endocrine ophthalmopathy 24
Acute myocardial infarction 24
Sjogren’s syndrome 23
B-cell small lymphocytic lymphoma 23
Conjunctivitis allergic 23
Sepsis 23
Colon cancer 23
Breast cancer female 22

Diseases starting with t

  • 2

    Traumatic pain

    Traumatic pain is physical pain that persists after a traumatic injury, often continuing long after the body’s initial wounds have healed and sometimes lasting for months or even years.

  • 1

    Tricuspid valve disease

    Tricuspid valve disease affects the valve between the two right heart chambers, preventing it from working properly. While it can remain silent for years, moderate to severe cases can damage the heart over time and require treatment ranging from medications to minimally invasive procedures.

  • 2

    Trigeminal neuralgia

    Trigeminal neuralgia causes sudden, severe facial pain that feels like an electric shock, often triggered by everyday activities like brushing teeth or touching the face. This chronic pain condition can be life-altering, but various treatments are available to help manage symptoms and restore quality of life.

  • 62

    Triple negative breast cancer

    Triple negative breast cancer is an aggressive form of breast cancer that doesn’t respond to the same treatments as other types. Understanding what makes this cancer different can help you make informed decisions about your care and feel more in control during your journey.

  • 1

    Triple positive breast cancer

    Triple positive breast cancer is a unique form of breast cancer where cancer cells respond to three specific factors: estrogen, progesterone, and a protein called HER2. While this diagnosis once meant facing an aggressive cancer with limited options, today’s treatments have transformed the outlook, offering multiple effective ways to fight the disease.

  • 5

    Trisomy 21

    Trisomy 21, commonly known as Down syndrome, is the most common chromosomal condition in humans, affecting about 1 in every 700 babies born in the United States—approximately 5,000 to 6,000 babies each year.

  • 3

    Tuberculosis

    Tuberculosis is a serious bacterial infection that most often affects the lungs, but it can be treated successfully with antibiotics if diagnosed and treated properly.

  • 8

    Tuberous sclerosis complex

    Tuberous sclerosis complex is a rare genetic disease that causes non-cancerous tumors to develop in multiple organs throughout the body, particularly in the brain, kidneys, heart, skin, and lungs. While some people live with few symptoms, others may experience seizures, developmental delays, and serious organ complications that require lifelong monitoring and care.

  • 1

    Tubulointerstitial nephritis

    Tubulointerstitial nephritis is inflammation that affects specific parts of the kidneys—the small tubes and surrounding tissue—but typically spares the tiny blood vessels that filter waste. This condition can develop suddenly or gradually, and while some people experience noticeable symptoms, others may have none at all.

  • 1

    Tumour of ampulla of Vater

    Tumour of the ampulla of Vater is a rare cancer that develops in a small but crucial opening where bile and digestive juices from your liver and pancreas meet before emptying into your small intestine. Although rare, affecting less than 1% of digestive system cancers, early detection can make a significant difference in treatment outcomes.

  • 1

    Tumour thrombosis

    Tumour thrombosis is a serious complication that occurs when cancer cells grow directly into blood vessels, forming a blockage made of tumour tissue rather than a typical blood clot.

  • 6

    Turner’s syndrome

    Turner’s syndrome is a genetic condition that affects only females, occurring when one of the X chromosomes is partially or completely missing. While there is no cure, early diagnosis and treatment can help girls and women with this condition lead healthy, productive lives.

  • 1

    Tympanic membrane hyperaemia

    Tympanic membrane hyperaemia refers to increased blood flow and redness in the thin layer of tissue that separates the outer ear from the middle ear, known as the eardrum. This condition is often an early sign of ear problems and can occur alongside various ear infections and inflammatory conditions.

  • 1

    Tympanic membrane perforation

    A tear or hole in the eardrum can happen from an infection, injury, or sudden pressure change, often causing pain, drainage, or hearing loss—but most perforations heal on their own within weeks.

  • 33

    Type 1 diabetes mellitus

    Type 1 diabetes is a lifelong condition where your body cannot produce insulin, a vital hormone that controls blood sugar levels. While it often begins in childhood, it can develop at any age and requires daily management with insulin therapy.

  • 67

    Type 2 diabetes mellitus

    Type 2 diabetes is a chronic condition where your body struggles to use insulin properly, causing blood sugar levels to rise. While it was once called “adult-onset diabetes,” it now affects people of all ages, including children, making it one of the most common health challenges worldwide.

  • 10

    Type IIa hyperlipidaemia

    Type IIa hyperlipidaemia is a genetic condition that causes dangerously high levels of cholesterol in the blood from birth, significantly increasing the risk of heart disease and stroke at a young age.

  • 1

    Type V hyperlipidaemia

    Type V hyperlipidaemia is a severe form of fat disorder in the blood that combines very high levels of triglycerides with the presence of multiple types of lipid particles, putting people at risk for serious complications like pancreatitis and heart disease.