Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease trials
Non-small cell lung cancer 228
Breast cancer 94
Obesity 86
Prostate cancer 73
Colorectal cancer 69
Ovarian cancer 66
Non-small cell lung cancer metastatic 66
Crohn’s disease 61
Type 2 diabetes mellitus 54
Rheumatoid arthritis 54
Triple negative breast cancer 52
Hormone receptor positive HER2 negative breast cancer 52
Asthma 51
Acute myeloid leukaemia 50
Squamous cell carcinoma of head and neck 50
Chronic kidney disease 49
Neoplasm 48
Colorectal cancer metastatic 47
Hepatocellular carcinoma 47
Systemic lupus erythematosus 40
Colitis ulcerative 40
Multiple sclerosis 39
Overweight 39
Dementia Alzheimer’s type 39
Gastric cancer 38
Myelodysplastic syndrome 37
Parkinson’s disease 37
HER2 positive breast cancer 37
Glioblastoma 37
Atrial fibrillation 34
Bladder cancer 34
Chronic obstructive pulmonary disease 33
Ischaemic stroke 33
Prostate cancer metastatic 33
Myasthenia gravis 32
Renal transplant 31
Type 1 diabetes mellitus 31
Head and neck cancer 31
Endometrial cancer 31
Malignant melanoma 31
Non-small cell lung cancer stage IV 31
Diffuse large B-cell lymphoma 31
Breast cancer metastatic 31
HIV infection 30
Dermatitis atopic 28
Cholangiocarcinoma 28
Coronary artery disease 28
Plasma cell myeloma 28
Pulmonary arterial hypertension 28
Neoplasm malignant 27
Rectal cancer 27
Renal cell carcinoma 26
Pancreatic carcinoma 26
Schizophrenia 26
Duchenne muscular dystrophy 25
Non-small cell lung cancer stage III 25
Follicular lymphoma 25
COVID-19 25
Migraine 24
Hormone receptor positive breast cancer 24
Idiopathic pulmonary fibrosis 24
Non-small cell lung cancer stage IIIB 24
Sepsis 24
Chronic lymphocytic leukaemia 24
Soft tissue sarcoma 24
Mantle cell lymphoma 23
Small cell lung cancer extensive stage 23
Colon cancer 23
Fallopian tube cancer 23
Influenza 22
Small cell lung cancer 21
Interstitial lung disease 21
Acute myocardial infarction 21
Oesophageal adenocarcinoma 21
Amyotrophic lateral sclerosis 21
Chronic rhinosinusitis with nasal polyps 20
Cystic fibrosis 20
Glioma 20
Myelofibrosis 19
Neuroblastoma 19
B-cell lymphoma 19
Sickle cell disease 19
Major depression 19
Procedural pain 19
Axial spondyloarthritis 18
Osteoarthritis 18
Breast cancer female 17
Critical illness 17
Acute kidney injury 17
Hereditary angioedema 17
Relapsing-remitting multiple sclerosis 16
Acute coronary syndrome 16
IgA nephropathy 16
Psoriasis 16
Gastrooesophageal cancer 16
Ewing’s sarcoma 16
Cardiac failure 16
Vitiligo 16
Transitional cell carcinoma 15
Giant cell arteritis 15

Diseases starting with p

  • 2

    Pseudoxanthoma elasticum

    Pseudoxanthoma elasticum is a rare genetic disorder that causes calcium and other minerals to accumulate in elastic tissues throughout the body, primarily affecting the skin, eyes, and blood vessels, and leading to a range of symptoms that require lifelong management.

  • 17

    Psoriasis

    Psoriasis is a chronic skin condition that causes thick, scaly patches to develop on the skin. While there’s no cure, many effective treatments can help manage symptoms and improve quality of life.

  • 5

    Psoriatic arthropathy

    Psoriatic arthropathy, also known as psoriatic arthritis, is a chronic inflammatory disease that causes pain, swelling, and stiffness in the joints. This condition often affects people who have psoriasis, a skin condition that creates scaly, itchy patches, although it can develop even without visible skin symptoms.

  • 1

    Psychogenic seizure

    Psychogenic seizures look and feel like epileptic seizures, but they are not caused by abnormal electrical activity in the brain. Instead, these episodes result from psychological distress and are real, involuntary events that can significantly disrupt daily life.

  • 0

    Psychological trauma

    Psychological trauma is an emotional response caused by severe distressing events that can affect anyone, leaving invisible wounds that may be more lasting than physical injuries. While most people experience natural recovery over time, understanding trauma and knowing effective ways to cope can help those struggling to reclaim their sense of safety and move forward.

  • 2

    Psychotic behaviour

    Psychotic behaviour occurs when people lose touch with reality, experiencing a disconnection that can involve seeing or hearing things that aren’t there, holding strong beliefs that aren’t true, or having confused patterns of thinking and speaking.

  • 10

    Psychotic disorder

    Psychotic disorders are serious mental illnesses where people lose touch with reality, experiencing false beliefs or perceiving things that aren’t there. These conditions affect how a person thinks, feels, and behaves, but with proper treatment, many people can recover and live full lives.

  • 0

    Pterygium

    Pterygium is a fleshy, triangular growth on the eye that develops mainly from prolonged sun exposure. While usually harmless, it can cause irritation and affect vision if left to grow across the cornea.

  • 0

    Pulmonary alveolar haemorrhage

    Pulmonary alveolar haemorrhage is a serious medical emergency where bleeding occurs within the tiny air sacs of the lungs, potentially causing severe breathing problems and requiring immediate medical attention.

  • 27

    Pulmonary arterial hypertension

    Pulmonary arterial hypertension is a serious condition where the small blood vessels in your lungs become narrow, making it harder for blood to flow through and causing your heart to work overtime.

  • 0

    Pulmonary congestion

    Pulmonary congestion is a serious condition where fluid accumulates in the lungs, making it difficult to breathe and preventing the body from getting enough oxygen. Understanding its causes, recognizing warning signs, and seeking prompt treatment can make a lifesaving difference.

  • 11

    Pulmonary embolism

    A pulmonary embolism is a serious medical emergency that occurs when a blood clot blocks an artery in the lungs, cutting off blood flow and oxygen supply. Quick treatment can save lives, but about 33% of people die before they receive diagnosis and treatment.

  • 7

    Pulmonary fibrosis

    Pulmonary fibrosis is a lung disease where tissue becomes scarred and thickened, making breathing progressively more difficult. While the exact cause is often unknown, understanding this condition and its management can help improve quality of life for those affected.

  • 11

    Pulmonary hypertension

    Pulmonary hypertension is a serious condition where blood pressure becomes dangerously high in the arteries between your heart and lungs, making it harder for blood to flow and forcing your heart to work much harder than normal.

  • 1

    Pulmonary resection

    Pulmonary resection is a major surgical procedure to remove part or all of a damaged or diseased lung. While it represents a serious operation, people can live with only one lung or with part of a lung removed, making this an important treatment option for various lung conditions.

  • 3

    Pulmonary sarcoidosis

    Pulmonary sarcoidosis is a condition where the immune system overreacts and forms tiny lumps of inflamed cells called granulomas in the lungs, affecting how well you can breathe and causing symptoms that range from mild to severe.

  • 3

    Pulmonary tuberculosis

    Pulmonary tuberculosis is a serious bacterial infection that mainly affects the lungs but can spread to other parts of the body. While highly contagious, it is both preventable and curable with proper treatment using antibiotics, though the infection requires long-term medication lasting several months.

  • 0

    Pulmonary vascular disorder

    Pulmonary vascular disorder is a broad term for any condition that affects the blood vessels between your heart and lungs, causing symptoms like shortness of breath and potentially leading to serious heart problems if left untreated.

  • 1

    Pulmonary venous thrombosis

    Pulmonary venous thrombosis is a rare but potentially life-threatening condition where blood clots form in the veins that carry oxygen-rich blood from the lungs to the heart. Unlike the more common blood clots in the legs, this condition often goes unnoticed until serious complications occur.

  • 0

    Pustular psoriasis

    Pustular psoriasis is a rare and serious form of psoriasis that causes painful, pus-filled blisters to appear on inflamed skin. While it affects only about 3% of people with psoriasis, this condition requires prompt medical attention, especially when it spreads quickly across large areas of the body.

  • 2

    Pyelonephritis

    Pyelonephritis is a bacterial infection of the kidneys that can cause serious health problems if not treated quickly. While most cases begin as bladder infections that spread upward, prompt treatment with antibiotics can prevent lasting kidney damage and life-threatening complications.

  • 3

    Pyelonephritis acute

    Acute pyelonephritis is a bacterial infection of the kidneys that can cause sudden and severe symptoms, including fever, flank pain, and nausea. While most cases can be treated successfully with antibiotics, prompt medical attention is essential to prevent serious complications.

  • 1

    Pyoderma

    Pyoderma gangrenosum is a rare and painful skin condition that causes large, open sores called ulcers. Despite its name, this condition is not an infection and is not contagious. It often begins as a small bump or blister that rapidly grows into a deep wound, requiring prompt medical attention to prevent complications.

  • 2

    Pyoderma gangrenosum

    Pyoderma gangrenosum is a rare and painful skin condition where small bumps or blisters rapidly turn into large, open sores that can be difficult to diagnose and treat, often affecting people with other health conditions like inflammatory bowel disease or arthritis.

  • 0

    Pyogenic sterile arthritis pyoderma gangrenosum and acne syndrome

    PAPA syndrome is a rare genetic condition that causes recurring joint inflammation, severe skin ulcers, and acne. It typically begins with joint problems in early childhood and develops skin symptoms during the teenage years.

  • 1

    Pyrexia

    Pyrexia, commonly known as fever, is your body’s natural way of fighting infection. When your temperature rises above normal, it signals that your immune system is working hard to combat invaders like viruses or bacteria. While uncomfortable, this protective response plays a crucial role in helping you recover from illness.

  • 4

    Pyruvate kinase deficiency anaemia

    Pyruvate kinase deficiency anaemia is a rare inherited blood disorder where red blood cells break down too quickly, causing a shortage of healthy cells to carry oxygen throughout the body. The condition affects people from birth, but symptoms can range from severe and life-threatening in newborns to so mild that they go unnoticed until adulthood.