Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 238
Breast cancer 131
Neoplasm 124
Plasma cell myeloma 122
Acute myeloid leukaemia 102
Neoplasm malignant 91
Prostate cancer 89
Colitis ulcerative 87
Obesity 81
Colorectal cancer metastatic 80
Crohn’s disease 76
Dementia Alzheimer’s type 75
Ovarian cancer 71
Type 2 diabetes mellitus 71
Colorectal cancer 69
Dermatitis atopic 66
Malignant melanoma 65
Breast cancer metastatic 65
Hepatocellular carcinoma 63
Triple negative breast cancer 62
Chronic lymphocytic leukaemia 60
Asthma 60
Non-small cell lung cancer metastatic 59
Rheumatoid arthritis 58
Squamous cell carcinoma of head and neck 58
HIV infection 57
Hormone receptor positive HER2 negative breast cancer 55
Osteoarthritis 55
Renal transplant 50
Pancreatic carcinoma 49
Chronic kidney disease 49
Ischaemic stroke 45
Atrial fibrillation 44
Parkinson’s disease 44
Systemic lupus erythematosus 43
Multiple sclerosis 42
Gastric cancer 42
Bladder cancer 40
Chronic obstructive pulmonary disease 40
Psoriasis 40
Non-small cell lung cancer stage IV 40
Oesophageal adenocarcinoma 40
Hormone-refractory prostate cancer 40
Migraine 39
Major depression 38
Endometrial cancer 38
Psoriatic arthropathy 37
Glioblastoma 36
Transitional cell carcinoma 36
Overweight 36
Myelodysplastic syndrome 36
Cardiac failure 35
Diffuse large B-cell lymphoma 35
Hormone receptor positive breast cancer 33
Systemic scleroderma 33
COVID-19 32
Cholangiocarcinoma 32
Schizophrenia 32
Type 1 diabetes mellitus 32
Hidradenitis 31
Prostate cancer metastatic 31
Head and neck cancer 31
Adenocarcinoma pancreas 30
Myasthenia gravis 30
HER2 positive breast cancer 30
Renal cell carcinoma 29
Rectal cancer 29
Cervix carcinoma 29
Coronary artery disease 29
Acute lymphocytic leukaemia 29
Pulmonary arterial hypertension 28
Follicular lymphoma 28
Plasma cell myeloma refractory 28
Oesophageal carcinoma 27
Depression 27
Bladder transitional cell carcinoma 27
Pancreatic carcinoma metastatic 27
Adenocarcinoma gastric 26
Pneumonia 26
Metastatic malignant melanoma 25
B-cell lymphoma 25
Acute myocardial infarction 25
Procedural pain 25
Interstitial lung disease 25
Myelofibrosis 24
Non-small cell lung cancer stage III 24
Colon cancer 24
Amyotrophic lateral sclerosis 24
Non-small cell lung cancer stage IIIB 24
Idiopathic pulmonary fibrosis 24
Small cell lung cancer 23
Breast cancer female 23
Sjogren’s syndrome 23
Fallopian tube cancer 23
Lung neoplasm malignant 22
Sepsis 22
Small cell lung cancer extensive stage 22
Endocrine ophthalmopathy 22
B-cell small lymphocytic lymphoma 22
Soft tissue sarcoma 22

Diseases starting with n

  • 1

    Non-Hodgkin’s lymphoma unspecified histology aggressive

    Aggressive non-Hodgkin lymphomas grow and spread quickly, requiring immediate treatment — but many patients can be cured with intensive combination therapy.

  • 1

    Non-Hodgkin’s lymphoma unspecified histology indolent

    Indolent non-Hodgkin’s lymphoma is a slow-growing type of blood cancer that develops in the lymphatic system. While it usually cannot be cured in advanced stages, most patients can live for many years with proper management.

  • 1

    Non-obstructive cardiomyopathy

    Non-obstructive cardiomyopathy is a form of heart muscle disease where the heart thickens but does not block blood flow in the same way as the obstructive form, yet it can still cause serious symptoms and complications that affect daily life.

  • 1

    Non-renal cell carcinoma of kidney

    Non-clear cell renal cell carcinoma represents a diverse group of kidney cancers that behave differently from the more common clear cell type, presenting unique challenges in diagnosis and treatment.

  • 238

    Non-small cell lung cancer

    Non-small cell lung cancer is the most common type of lung cancer, accounting for about 80% to 85% of all lung cancer cases. It happens when normal cells in your lungs change and grow out of control, usually developing more slowly than other forms of lung cancer but often spreading before symptoms appear.

  • 59

    Non-small cell lung cancer metastatic

    When non-small cell lung cancer spreads beyond the lungs to distant parts of the body, it becomes metastatic—a condition that brings unique challenges but also growing hope through advancing treatments and supportive care approaches.

  • 12

    Non-small cell lung cancer recurrent

    Recurrent non-small cell lung cancer means the cancer has returned after treatment. Even after successful treatment that achieves remission, between 30% and 55% of patients develop recurrence, though modern treatments offer hope and new options for managing the disease when it returns.

  • 4

    Non-small cell lung cancer stage I

    Stage I non-small cell lung cancer is an early form of the disease where the tumor is small and has not spread beyond the lung. With proper treatment, many people with this stage have a good chance of living for many years.

  • 7

    Non-small cell lung cancer stage II

    Stage II non-small cell lung cancer means doctors have found one or more tumors in your lung that have started to spread, but only within the lung or to nearby lymph nodes. While the cancer is more extensive than stage I, surgery and other treatments can often remove it successfully, giving many patients a good chance at longer survival.

  • 24

    Non-small cell lung cancer stage III

    Stage 3 non-small cell lung cancer represents a complex form of lung disease where cancer has spread beyond the lungs to nearby tissues and lymph nodes, but not to distant organs. About 30% of people with non-small cell lung cancer are diagnosed at this stage, facing a challenging but potentially treatable condition.

  • 12

    Non-small cell lung cancer stage IIIA

    Stage IIIA non-small cell lung cancer represents a complex middle ground in cancer care—the disease has spread beyond the lungs to nearby lymph nodes but has not reached distant parts of the body. About 30% of people with non-small cell lung cancer are diagnosed at stage 3, facing challenging but potentially treatable disease that requires a carefully coordinated approach from multiple medical specialists.

  • 24

    Non-small cell lung cancer stage IIIB

    Stage IIIB non-small cell lung cancer represents an advanced form of the disease where cancer has spread beyond the lung to nearby structures and lymph nodes, yet has not reached distant organs. Understanding this stage and the available treatment options is essential for making informed decisions about care.

  • 40

    Non-small cell lung cancer stage IV

    Stage IV non-small cell lung cancer means the disease has spread from the lungs to distant areas of the body. Although it usually can’t be cured, a variety of treatments can slow the cancer’s growth and help manage symptoms.

  • 0

    Noninfective chorioretinitis

    Noninfective chorioretinitis is an inflammatory condition affecting the back of the eye that can seriously threaten your vision if left untreated. Unlike infections, this condition stems from the body’s own immune system or other non-infectious causes.

  • 3

    Noonan syndrome

    Noonan syndrome is a genetic condition that affects many parts of the body, causing distinctive facial features, heart problems, short stature, and other health challenges that vary widely from person to person.

  • 1

    Normal pressure hydrocephalus

    Normal pressure hydrocephalus is a brain condition that happens when fluid builds up inside your skull, causing walking problems, memory difficulties, and loss of bladder control. While these symptoms can look like dementia or Parkinson’s disease, this condition is sometimes treatable and even reversible with surgery.

  • 0

    Notalgia paraesthetica

    Notalgia paresthetica is a nerve disorder that causes intense itching, burning, or tingling in a specific patch of skin on your upper back, usually between your shoulder blade and spine. Although it can be uncomfortable and frustrating, the condition is not dangerous to your health.

  • 2

    NTRK gene fusion overexpression

    NTRK gene fusions represent a rare but critical genetic change that can drive cancer development across many different types of tumors, affecting both adults and children.