Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease trials
Non-small cell lung cancer 228
Breast cancer 94
Obesity 86
Prostate cancer 73
Colorectal cancer 69
Ovarian cancer 66
Non-small cell lung cancer metastatic 66
Crohn’s disease 61
Type 2 diabetes mellitus 54
Rheumatoid arthritis 54
Triple negative breast cancer 52
Hormone receptor positive HER2 negative breast cancer 52
Asthma 51
Acute myeloid leukaemia 50
Squamous cell carcinoma of head and neck 50
Chronic kidney disease 49
Neoplasm 48
Colorectal cancer metastatic 47
Hepatocellular carcinoma 47
Systemic lupus erythematosus 40
Colitis ulcerative 40
Multiple sclerosis 39
Overweight 39
Dementia Alzheimer’s type 39
Gastric cancer 38
Myelodysplastic syndrome 37
Parkinson’s disease 37
HER2 positive breast cancer 37
Glioblastoma 37
Atrial fibrillation 34
Bladder cancer 34
Chronic obstructive pulmonary disease 33
Ischaemic stroke 33
Prostate cancer metastatic 33
Myasthenia gravis 32
Renal transplant 31
Type 1 diabetes mellitus 31
Head and neck cancer 31
Endometrial cancer 31
Malignant melanoma 31
Non-small cell lung cancer stage IV 31
Diffuse large B-cell lymphoma 31
Breast cancer metastatic 31
HIV infection 30
Dermatitis atopic 28
Cholangiocarcinoma 28
Coronary artery disease 28
Plasma cell myeloma 28
Pulmonary arterial hypertension 28
Neoplasm malignant 27
Rectal cancer 27
Renal cell carcinoma 26
Pancreatic carcinoma 26
Schizophrenia 26
Duchenne muscular dystrophy 25
Non-small cell lung cancer stage III 25
Follicular lymphoma 25
COVID-19 25
Migraine 24
Hormone receptor positive breast cancer 24
Idiopathic pulmonary fibrosis 24
Non-small cell lung cancer stage IIIB 24
Sepsis 24
Chronic lymphocytic leukaemia 24
Soft tissue sarcoma 24
Mantle cell lymphoma 23
Small cell lung cancer extensive stage 23
Colon cancer 23
Fallopian tube cancer 23
Influenza 22
Small cell lung cancer 21
Interstitial lung disease 21
Acute myocardial infarction 21
Oesophageal adenocarcinoma 21
Amyotrophic lateral sclerosis 21
Chronic rhinosinusitis with nasal polyps 20
Cystic fibrosis 20
Glioma 20
Myelofibrosis 19
Neuroblastoma 19
B-cell lymphoma 19
Sickle cell disease 19
Major depression 19
Procedural pain 19
Axial spondyloarthritis 18
Osteoarthritis 18
Breast cancer female 17
Critical illness 17
Acute kidney injury 17
Hereditary angioedema 17
Relapsing-remitting multiple sclerosis 16
Acute coronary syndrome 16
IgA nephropathy 16
Psoriasis 16
Gastrooesophageal cancer 16
Ewing’s sarcoma 16
Cardiac failure 16
Vitiligo 16
Transitional cell carcinoma 15
Giant cell arteritis 15

Diseases starting with n

  • 1

    Non-Hodgkin’s lymphoma unspecified histology aggressive

    Aggressive non-Hodgkin lymphomas grow and spread quickly, requiring immediate treatment — but many patients can be cured with intensive combination therapy.

  • 1

    Non-Hodgkin’s lymphoma unspecified histology indolent

    Indolent non-Hodgkin’s lymphoma is a slow-growing type of blood cancer that develops in the lymphatic system. While it usually cannot be cured in advanced stages, most patients can live for many years with proper management.

  • 1

    Non-obstructive cardiomyopathy

    Non-obstructive cardiomyopathy is a form of heart muscle disease where the heart thickens but does not block blood flow in the same way as the obstructive form, yet it can still cause serious symptoms and complications that affect daily life.

  • 2

    Non-renal cell carcinoma of kidney

    Non-clear cell renal cell carcinoma represents a diverse group of kidney cancers that behave differently from the more common clear cell type, presenting unique challenges in diagnosis and treatment.

  • 225

    Non-small cell lung cancer

    Non-small cell lung cancer is the most common type of lung cancer, accounting for about 80% to 85% of all lung cancer cases. It happens when normal cells in your lungs change and grow out of control, usually developing more slowly than other forms of lung cancer but often spreading before symptoms appear.

  • 63

    Non-small cell lung cancer metastatic

    When non-small cell lung cancer spreads beyond the lungs to distant parts of the body, it becomes metastatic—a condition that brings unique challenges but also growing hope through advancing treatments and supportive care approaches.

  • 10

    Non-small cell lung cancer recurrent

    Recurrent non-small cell lung cancer means the cancer has returned after treatment. Even after successful treatment that achieves remission, between 30% and 55% of patients develop recurrence, though modern treatments offer hope and new options for managing the disease when it returns.

  • 3

    Non-small cell lung cancer stage I

    Stage I non-small cell lung cancer is an early form of the disease where the tumor is small and has not spread beyond the lung. With proper treatment, many people with this stage have a good chance of living for many years.

  • 8

    Non-small cell lung cancer stage II

    Stage II non-small cell lung cancer means doctors have found one or more tumors in your lung that have started to spread, but only within the lung or to nearby lymph nodes. While the cancer is more extensive than stage I, surgery and other treatments can often remove it successfully, giving many patients a good chance at longer survival.

  • 26

    Non-small cell lung cancer stage III

    Stage 3 non-small cell lung cancer represents a complex form of lung disease where cancer has spread beyond the lungs to nearby tissues and lymph nodes, but not to distant organs. About 30% of people with non-small cell lung cancer are diagnosed at this stage, facing a challenging but potentially treatable condition.

  • 13

    Non-small cell lung cancer stage IIIA

    Stage IIIA non-small cell lung cancer represents a complex middle ground in cancer care—the disease has spread beyond the lungs to nearby lymph nodes but has not reached distant parts of the body. About 30% of people with non-small cell lung cancer are diagnosed at stage 3, facing challenging but potentially treatable disease that requires a carefully coordinated approach from multiple medical specialists.

  • 23

    Non-small cell lung cancer stage IIIB

    Stage IIIB non-small cell lung cancer represents an advanced form of the disease where cancer has spread beyond the lung to nearby structures and lymph nodes, yet has not reached distant organs. Understanding this stage and the available treatment options is essential for making informed decisions about care.

  • 32

    Non-small cell lung cancer stage IV

    Stage IV non-small cell lung cancer means the disease has spread from the lungs to distant areas of the body. Although it usually can’t be cured, a variety of treatments can slow the cancer’s growth and help manage symptoms.

  • 0

    Noninfective chorioretinitis

    Noninfective chorioretinitis is an inflammatory condition affecting the back of the eye that can seriously threaten your vision if left untreated. Unlike infections, this condition stems from the body’s own immune system or other non-infectious causes.

  • 1

    Noonan syndrome

    Noonan syndrome is a genetic condition that affects many parts of the body, causing distinctive facial features, heart problems, short stature, and other health challenges that vary widely from person to person.

  • 1

    Normal pressure hydrocephalus

    Normal pressure hydrocephalus is a brain condition that happens when fluid builds up inside your skull, causing walking problems, memory difficulties, and loss of bladder control. While these symptoms can look like dementia or Parkinson’s disease, this condition is sometimes treatable and even reversible with surgery.

  • 1

    Notalgia paraesthetica

    Notalgia paresthetica is a nerve disorder that causes intense itching, burning, or tingling in a specific patch of skin on your upper back, usually between your shoulder blade and spine. Although it can be uncomfortable and frustrating, the condition is not dangerous to your health.

  • 2

    NTRK gene fusion overexpression

    NTRK gene fusions represent a rare but critical genetic change that can drive cancer development across many different types of tumors, affecting both adults and children.