Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease Trials
Non-small cell lung cancer 257
Breast cancer 130
Neoplasm 124
Plasma cell myeloma 124
Acute myeloid leukaemia 103
Neoplasm malignant 102
Colitis ulcerative 93
Prostate cancer 91
Colorectal cancer metastatic 84
Obesity 84
Colorectal cancer 76
Crohn’s disease 76
Ovarian cancer 76
Dementia Alzheimer’s type 74
Hepatocellular carcinoma 73
Malignant melanoma 69
Breast cancer metastatic 68
Type 2 diabetes mellitus 67
Dermatitis atopic 65
Triple negative breast cancer 62
Chronic lymphocytic leukaemia 62
Squamous cell carcinoma of head and neck 60
Rheumatoid arthritis 58
HIV infection 58
Non-small cell lung cancer metastatic 57
Asthma 57
Osteoarthritis 56
Hormone receptor positive HER2 negative breast cancer 54
Renal transplant 51
Pancreatic carcinoma 51
Chronic kidney disease 50
Multiple sclerosis 48
Chronic obstructive pulmonary disease 46
Systemic lupus erythematosus 46
Hormone-refractory prostate cancer 46
Ischaemic stroke 46
Parkinson’s disease 46
Atrial fibrillation 44
Bladder cancer 42
Gastric cancer 42
Diffuse large B-cell lymphoma 41
Psoriasis 41
Migraine 41
Non-small cell lung cancer stage IV 41
Oesophageal adenocarcinoma 40
Glioblastoma 38
Psoriatic arthropathy 38
Major depression 38
Myelodysplastic syndrome 38
Transitional cell carcinoma 38
Prostate cancer metastatic 37
Endometrial cancer 37
Overweight 36
Cholangiocarcinoma 35
Cardiac failure 35
Acute lymphocytic leukaemia 35
Hormone receptor positive breast cancer 34
Systemic scleroderma 34
COVID-19 34
HER2 positive breast cancer 33
Type 1 diabetes mellitus 33
Hidradenitis 33
Schizophrenia 32
Myasthenia gravis 32
Renal cell carcinoma 32
Head and neck cancer 32
Plasma cell myeloma refractory 32
Adenocarcinoma pancreas 31
Coronary artery disease 31
Cervix carcinoma 30
Follicular lymphoma 30
Rectal cancer 30
Depression 29
Pulmonary arterial hypertension 29
Pancreatic carcinoma metastatic 29
Idiopathic pulmonary fibrosis 28
Small cell lung cancer extensive stage 27
Oesophageal carcinoma 27
Bladder transitional cell carcinoma 27
Metastatic malignant melanoma 26
Interstitial lung disease 26
Non-small cell lung cancer stage III 25
B-cell lymphoma 25
Fallopian tube cancer 25
Pneumonia 25
Lung neoplasm malignant 25
Adenocarcinoma gastric 25
Myelofibrosis 24
Small cell lung cancer 24
Amyotrophic lateral sclerosis 24
Endocrine ophthalmopathy 24
Acute myocardial infarction 24
Procedural pain 24
Soft tissue sarcoma 24
Sepsis 23
Colon cancer 23
Sjogren’s syndrome 23
B-cell small lymphocytic lymphoma 23
Conjunctivitis allergic 23
Cardiac amyloidosis 22

Diseases starting with h

  • 14

    Hypertrophic cardiomyopathy

    Hypertrophic cardiomyopathy is a heart condition where the muscle becomes abnormally thick, making it harder for the heart to pump blood properly. While many people live without symptoms, this genetic disease can lead to serious complications, including sudden cardiac death, particularly in young people and athletes.

  • 1

    Hypertrophic scar

    A hypertrophic scar is a thick, raised scar that develops when your body produces too much collagen during the healing process. Unlike normal scars that fade and flatten over time, these scars remain elevated and can cause itching, pain, and movement restrictions, though they typically stay within the boundaries of the original wound.

  • 0

    Hypervolaemia

    Hypervolaemia occurs when your body holds onto too much fluid. This excess can cause swelling, breathing difficulties, and potentially serious heart problems. Understanding the causes and knowing how to manage this condition can help protect your health.

  • 1

    Hypoaesthesia

    Hypoaesthesia is a decreased sensitivity to touch that can make you feel strangely numb or insensitive in parts of your body. While often temporary and harmless, this reduced sensation can sometimes indicate a more serious underlying condition that requires medical attention.

  • 0

    Hypoalbuminaemia

    Hypoalbuminaemia is a widespread condition where the level of albumin protein in your blood falls below normal levels. This protein plays essential roles in keeping fluid inside blood vessels and moving important substances throughout your body. The condition is especially common among people who are hospitalized or seriously ill, and it often signals an underlying health problem that needs attention.

  • 2

    Hypocalcaemia

    Hypocalcaemia is a treatable condition that occurs when calcium levels in the blood fall below normal. While some people experience no symptoms at all, others may face serious complications affecting the nervous system and heart if left untreated.

  • 3

    Hypochondroplasia

    Hypochondroplasia is a genetic condition that affects how bones grow, leading to short stature and shortened limbs. While it shares similarities with achondroplasia, its features are often milder and may not be noticed until early childhood.

  • 1

    Hypochromic anaemia

    Hypochromic anaemia is a blood condition where red blood cells appear paler than normal due to lower levels of haemoglobin, the protein that carries oxygen throughout the body. This condition most commonly occurs because of iron deficiency, though other causes exist, and affects millions of people worldwide, particularly women and young children.

  • 2

    Hypoglycaemia

    Hypoglycaemia is a condition where blood sugar drops below safe levels, causing symptoms that range from shakiness and sweating to confusion and, in severe cases, loss of consciousness. While most common in people with diabetes who take insulin or certain medications, understanding how to recognize and treat low blood sugar quickly can prevent serious complications.

  • 5

    Hypogonadism male

    Male hypogonadism is a condition where the body doesn’t produce enough testosterone, the hormone essential for male development and characteristics, or enough sperm, or both. This condition can develop before birth, during puberty, or in adulthood, affecting physical development, sexual function, and overall health.

  • 1

    Hypomagnesaemia

    Hypomagnesemia is a condition where your blood contains less magnesium than normal. This essential mineral plays a vital role in keeping your heart, brain, and muscles working properly, and low levels can lead to symptoms ranging from muscle cramps to dangerous heart rhythm problems.

  • 1

    Hyponatraemia

    Hyponatraemia occurs when the level of sodium in your blood drops too low, creating an imbalance between water and sodium in your body. This common condition can range from mild with few symptoms to severe and life-threatening, affecting your brain and other vital organs.

  • 7

    Hypoparathyroidism

    Hypoparathyroidism is a rare condition where the body doesn’t make enough parathyroid hormone, leading to low calcium levels in the blood. While most cases occur after neck surgery, this treatable condition can be managed with proper care and supplements.

  • 6

    Hypophosphatasia

    Hypophosphatasia is a rare genetic condition that causes bones and teeth to become soft and weak, affecting people in very different ways depending on when symptoms first appear and how severe they are.

  • 1

    Hypopituitarism

    Hypopituitarism is a rare condition where your pituitary gland doesn’t produce enough of the hormones your body needs to function properly. This can affect growth, metabolism, reproduction, and many other vital processes, requiring careful diagnosis and often lifelong treatment.

  • 0

    Hypoplastic left heart syndrome

    Hypoplastic left heart syndrome is a serious heart condition that babies are born with, where the left side of the heart doesn’t develop properly and is too small to pump blood effectively to the body.

  • 4

    Hypotension

    Low blood pressure, also known as hypotension, occurs when blood flows through your blood vessels at lower than normal pressures. While many people have naturally low blood pressure without problems, sometimes it can signal an underlying health issue or cause troubling symptoms like dizziness and fainting.

  • 3

    Hypothyroidism

    Hypothyroidism, also called underactive thyroid, occurs when your thyroid gland doesn’t produce enough thyroid hormones to meet your body’s needs. This common condition affects nearly 5 out of 100 Americans and can slow down many of your body’s functions, causing fatigue, weight gain, and other symptoms that develop gradually over time.

  • 0

    Hypotonia

    Hypotonia is a condition where muscles have less tension than normal, often making infants appear “floppy” or limp when held. While the condition itself is easily recognized, finding out what causes it can be challenging, and early diagnosis and treatment play an important role in helping children develop their movement skills.

  • 1

    Hypotransferrinaemia

    Hypotransferrinaemia is an extremely rare genetic blood disorder that causes a puzzling combination: severe anemia despite iron overload in the body. This life-threatening condition requires lifelong treatment with regular plasma infusions to survive.

  • 3

    Hypoxia

    Hypoxia is a serious medical condition where your body’s tissues don’t receive enough oxygen. When oxygen levels drop too low, you might feel confused, restless, or struggle to breathe, and your skin may turn bluish. This condition can become life-threatening within minutes if not treated promptly.

  • 2

    Hypoxic-ischaemic encephalopathy

    Hypoxic-ischaemic encephalopathy is a serious brain injury that occurs when a newborn’s brain doesn’t receive enough oxygen and blood during birth or shortly after. While some children recover completely, others may face lifelong challenges affecting their movement, learning, and development.

  • 2

    Hysterectomy

    A hysterectomy is a surgical procedure to remove the uterus. After this surgery, you can no longer become pregnant and will not have menstrual periods. It is one of the most common surgeries for women, with approximately 600,000 performed each year in the United States.