Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease trials
Non-small cell lung cancer 240
Breast cancer 99
Obesity 92
Prostate cancer 77
Colorectal cancer 69
Ovarian cancer 68
Crohn’s disease 67
Non-small cell lung cancer metastatic 64
Rheumatoid arthritis 55
Squamous cell carcinoma of head and neck 54
Triple negative breast cancer 54
Chronic kidney disease 50
Asthma 50
Hepatocellular carcinoma 47
Neoplasm 47
Acute myeloid leukaemia 47
Colorectal cancer metastatic 46
Overweight 45
Multiple sclerosis 43
Colitis ulcerative 40
Parkinson’s disease 40
HER2 positive breast cancer 39
Gastric cancer 38
Myelodysplastic syndrome 38
Dementia Alzheimer’s type 37
Glioblastoma 36
Bladder cancer 34
Atrial fibrillation 34
Prostate cancer metastatic 34
Renal transplant 33
Ischaemic stroke 33
Diffuse large B-cell lymphoma 32
Chronic obstructive pulmonary disease 32
Head and neck cancer 32
Non-small cell lung cancer stage IV 31
Breast cancer metastatic 30
Coronary artery disease 29
Myasthenia gravis 29
Malignant melanoma 29
Endometrial cancer 28
Cholangiocarcinoma 28
Rectal cancer 27
Pulmonary arterial hypertension 27
Dermatitis atopic 27
Idiopathic pulmonary fibrosis 27
Soft tissue sarcoma 26
Non-small cell lung cancer stage III 26
Plasma cell myeloma 25
Pancreatic carcinoma 25
Small cell lung cancer extensive stage 25
Sepsis 25
Renal cell carcinoma 25
Schizophrenia 24
COVID-19 24
Duchenne muscular dystrophy 24
Non-small cell lung cancer stage IIIB 24
Follicular lymphoma 24
Hormone receptor positive breast cancer 24
Fallopian tube cancer 23
Amyotrophic lateral sclerosis 23
Mantle cell lymphoma 23
Influenza 22
Neoplasm malignant 22
Chronic lymphocytic leukaemia 21
Acute myocardial infarction 21
Major depression 21
Small cell lung cancer 21
Sickle cell disease 21
Interstitial lung disease 21
Cystic fibrosis 21
Breast cancer female 20
Osteoarthritis 20
Glioma 20
Neuroblastoma 20
Chronic rhinosinusitis with nasal polyps 20
Oesophageal adenocarcinoma 20
Myelofibrosis 19
B-cell lymphoma 19
Critical illness 18
Procedural pain 18
Acute kidney injury 18
Psoriasis 18
Axial spondyloarthritis 18
Acute coronary syndrome 17
Vitiligo 17
Hereditary angioedema 17
Relapsing-remitting multiple sclerosis 17
Ewing’s sarcoma 17
IgA nephropathy 17
Gastrooesophageal cancer 16
Juvenile idiopathic arthritis 16
Cardiac failure 16
Uveal melanoma 16
Chronic hepatitis B 16
Allogenic stem cell transplantation 15
Giant cell arteritis 15
Chronic spontaneous urticaria 15
Cardiac arrest 15
Septic shock 14
Malignant melanoma stage III 14

Diseases starting with h

  • 11

    Hypertrophic cardiomyopathy

    Hypertrophic cardiomyopathy is a heart condition where the muscle becomes abnormally thick, making it harder for the heart to pump blood properly. While many people live without symptoms, this genetic disease can lead to serious complications, including sudden cardiac death, particularly in young people and athletes.

  • 1

    Hypertrophic scar

    A hypertrophic scar is a thick, raised scar that develops when your body produces too much collagen during the healing process. Unlike normal scars that fade and flatten over time, these scars remain elevated and can cause itching, pain, and movement restrictions, though they typically stay within the boundaries of the original wound.

  • 0

    Hypervolaemia

    Hypervolaemia occurs when your body holds onto too much fluid. This excess can cause swelling, breathing difficulties, and potentially serious heart problems. Understanding the causes and knowing how to manage this condition can help protect your health.

  • 0

    Hypoaesthesia

    Hypoaesthesia is a decreased sensitivity to touch that can make you feel strangely numb or insensitive in parts of your body. While often temporary and harmless, this reduced sensation can sometimes indicate a more serious underlying condition that requires medical attention.

  • 0

    Hypoalbuminaemia

    Hypoalbuminaemia is a widespread condition where the level of albumin protein in your blood falls below normal levels. This protein plays essential roles in keeping fluid inside blood vessels and moving important substances throughout your body. The condition is especially common among people who are hospitalized or seriously ill, and it often signals an underlying health problem that needs attention.

  • 0

    Hypocalcaemia

    Hypocalcaemia is a treatable condition that occurs when calcium levels in the blood fall below normal. While some people experience no symptoms at all, others may face serious complications affecting the nervous system and heart if left untreated.

  • 5

    Hypochondroplasia

    Hypochondroplasia is a genetic condition that affects how bones grow, leading to short stature and shortened limbs. While it shares similarities with achondroplasia, its features are often milder and may not be noticed until early childhood.

  • 0

    Hypochromic anaemia

    Hypochromic anaemia is a blood condition where red blood cells appear paler than normal due to lower levels of haemoglobin, the protein that carries oxygen throughout the body. This condition most commonly occurs because of iron deficiency, though other causes exist, and affects millions of people worldwide, particularly women and young children.

  • 1

    Hypoglycaemia

    Hypoglycaemia is a condition where blood sugar drops below safe levels, causing symptoms that range from shakiness and sweating to confusion and, in severe cases, loss of consciousness. While most common in people with diabetes who take insulin or certain medications, understanding how to recognize and treat low blood sugar quickly can prevent serious complications.

  • 5

    Hypogonadism male

    Male hypogonadism is a condition where the body doesn’t produce enough testosterone, the hormone essential for male development and characteristics, or enough sperm, or both. This condition can develop before birth, during puberty, or in adulthood, affecting physical development, sexual function, and overall health.

  • 1

    Hypomagnesaemia

    Hypomagnesemia is a condition where your blood contains less magnesium than normal. This essential mineral plays a vital role in keeping your heart, brain, and muscles working properly, and low levels can lead to symptoms ranging from muscle cramps to dangerous heart rhythm problems.

  • 1

    Hyponatraemia

    Hyponatraemia occurs when the level of sodium in your blood drops too low, creating an imbalance between water and sodium in your body. This common condition can range from mild with few symptoms to severe and life-threatening, affecting your brain and other vital organs.

  • 8

    Hypoparathyroidism

    Hypoparathyroidism is a rare condition where the body doesn’t make enough parathyroid hormone, leading to low calcium levels in the blood. While most cases occur after neck surgery, this treatable condition can be managed with proper care and supplements.

  • 5

    Hypophosphatasia

    Hypophosphatasia is a rare genetic condition that causes bones and teeth to become soft and weak, affecting people in very different ways depending on when symptoms first appear and how severe they are.

  • 1

    Hypopituitarism

    Hypopituitarism is a rare condition where your pituitary gland doesn’t produce enough of the hormones your body needs to function properly. This can affect growth, metabolism, reproduction, and many other vital processes, requiring careful diagnosis and often lifelong treatment.

  • 1

    Hypoplastic left heart syndrome

    Hypoplastic left heart syndrome is a serious heart condition that babies are born with, where the left side of the heart doesn’t develop properly and is too small to pump blood effectively to the body.

  • 3

    Hypotension

    Low blood pressure, also known as hypotension, occurs when blood flows through your blood vessels at lower than normal pressures. While many people have naturally low blood pressure without problems, sometimes it can signal an underlying health issue or cause troubling symptoms like dizziness and fainting.

  • 3

    Hypothyroidism

    Hypothyroidism, also called underactive thyroid, occurs when your thyroid gland doesn’t produce enough thyroid hormones to meet your body’s needs. This common condition affects nearly 5 out of 100 Americans and can slow down many of your body’s functions, causing fatigue, weight gain, and other symptoms that develop gradually over time.

  • 0

    Hypotonia

    Hypotonia is a condition where muscles have less tension than normal, often making infants appear “floppy” or limp when held. While the condition itself is easily recognized, finding out what causes it can be challenging, and early diagnosis and treatment play an important role in helping children develop their movement skills.

  • 1

    Hypotransferrinaemia

    Hypotransferrinaemia is an extremely rare genetic blood disorder that causes a puzzling combination: severe anemia despite iron overload in the body. This life-threatening condition requires lifelong treatment with regular plasma infusions to survive.

  • 2

    Hypoxia

    Hypoxia is a serious medical condition where your body’s tissues don’t receive enough oxygen. When oxygen levels drop too low, you might feel confused, restless, or struggle to breathe, and your skin may turn bluish. This condition can become life-threatening within minutes if not treated promptly.

  • 0

    Hypoxic-ischaemic encephalopathy

    Hypoxic-ischaemic encephalopathy is a serious brain injury that occurs when a newborn’s brain doesn’t receive enough oxygen and blood during birth or shortly after. While some children recover completely, others may face lifelong challenges affecting their movement, learning, and development.

  • 2

    Hysterectomy

    A hysterectomy is a surgical procedure to remove the uterus. After this surgery, you can no longer become pregnant and will not have menstrual periods. It is one of the most common surgeries for women, with approximately 600,000 performed each year in the United States.