Explore popular diseases in clinical trials

Check which popular diseases are currently being frequently studied.

See also our rare diseases glossary and drug database.

Starting by letter

To open the diseases glossary, select a letter from the list below.

Most popular diseases

The list below features the most popular diseases currently involved in ongoing clinical trials.

Disease trials
Non-small cell lung cancer 228
Breast cancer 94
Obesity 86
Prostate cancer 73
Colorectal cancer 69
Ovarian cancer 66
Non-small cell lung cancer metastatic 66
Crohn’s disease 61
Type 2 diabetes mellitus 54
Rheumatoid arthritis 54
Triple negative breast cancer 52
Hormone receptor positive HER2 negative breast cancer 52
Asthma 51
Acute myeloid leukaemia 50
Squamous cell carcinoma of head and neck 50
Chronic kidney disease 49
Neoplasm 48
Colorectal cancer metastatic 47
Hepatocellular carcinoma 47
Systemic lupus erythematosus 40
Colitis ulcerative 40
Multiple sclerosis 39
Overweight 39
Dementia Alzheimer’s type 39
Gastric cancer 38
Myelodysplastic syndrome 37
Parkinson’s disease 37
HER2 positive breast cancer 37
Glioblastoma 37
Atrial fibrillation 34
Bladder cancer 34
Chronic obstructive pulmonary disease 33
Ischaemic stroke 33
Prostate cancer metastatic 33
Myasthenia gravis 32
Renal transplant 31
Type 1 diabetes mellitus 31
Head and neck cancer 31
Endometrial cancer 31
Malignant melanoma 31
Non-small cell lung cancer stage IV 31
Diffuse large B-cell lymphoma 31
Breast cancer metastatic 31
HIV infection 30
Dermatitis atopic 28
Cholangiocarcinoma 28
Coronary artery disease 28
Plasma cell myeloma 28
Pulmonary arterial hypertension 28
Neoplasm malignant 27
Rectal cancer 27
Renal cell carcinoma 26
Pancreatic carcinoma 26
Schizophrenia 26
Duchenne muscular dystrophy 25
Non-small cell lung cancer stage III 25
Follicular lymphoma 25
COVID-19 25
Migraine 24
Hormone receptor positive breast cancer 24
Idiopathic pulmonary fibrosis 24
Non-small cell lung cancer stage IIIB 24
Sepsis 24
Chronic lymphocytic leukaemia 24
Soft tissue sarcoma 24
Mantle cell lymphoma 23
Small cell lung cancer extensive stage 23
Colon cancer 23
Fallopian tube cancer 23
Influenza 22
Small cell lung cancer 21
Interstitial lung disease 21
Acute myocardial infarction 21
Oesophageal adenocarcinoma 21
Amyotrophic lateral sclerosis 21
Chronic rhinosinusitis with nasal polyps 20
Cystic fibrosis 20
Glioma 20
Myelofibrosis 19
Neuroblastoma 19
B-cell lymphoma 19
Sickle cell disease 19
Major depression 19
Procedural pain 19
Axial spondyloarthritis 18
Osteoarthritis 18
Breast cancer female 17
Critical illness 17
Acute kidney injury 17
Hereditary angioedema 17
Relapsing-remitting multiple sclerosis 16
Acute coronary syndrome 16
IgA nephropathy 16
Psoriasis 16
Gastrooesophageal cancer 16
Ewing’s sarcoma 16
Cardiac failure 16
Vitiligo 16
Transitional cell carcinoma 15
Giant cell arteritis 15

Diseases starting with b

  • 2

    Bone sarcoma

    Bone sarcoma is a rare type of cancer that starts in the bones themselves, affecting fewer than 1% of all cancer diagnoses, yet carrying significant challenges for those who face it.

  • 3

    Borderline personality disorder

    Borderline personality disorder is a mental health condition that affects how you feel about yourself and others, making relationships and everyday life challenging. But with effective treatment, many people with this condition learn to live stabler, more fulfilling lives.

  • 1

    BRAF gene mutation

    A mutation in the BRAF gene can lead to uncontrolled cell growth and the development of cancer in various organs throughout the body. Understanding whether your cancer has this genetic change is important because it can guide doctors toward the most effective treatment options for you.

  • 1

    Brain abscess

    A brain abscess is a dangerous collection of pus within the brain that requires urgent medical attention. This life-threatening infection can develop when bacteria or fungi invade brain tissue, causing swelling that puts pressure on the brain and disrupts its normal function.

  • 0

    Brain cancer metastatic

    Brain metastases occur when cancer from another part of your body spreads to your brain, forming one or more new tumors that can affect how you think, move, and feel.

  • 4

    Brain injury

    Every 9 seconds, someone in the United States sustains a brain injury—an event that can change everything about a person in a matter of seconds. While brain injuries affect millions worldwide each year, no two injuries are exactly alike, making each person’s journey unique.

  • 2

    Brain neoplasm

    Brain neoplasms are abnormal growths of cells in or around the brain that can range from slow-growing masses to aggressive cancers, affecting people of all ages and requiring specialized care tailored to each individual tumor type.

  • 1

    Brain neoplasm malignant

    Malignant brain tumors are cancerous growths that develop in the brain and require swift medical intervention. These aggressive tumors can grow quickly and invade healthy brain tissue, affecting thousands of lives each year.

  • 6

    Brain stem glioma

    Brain stem glioma is a type of tumor that develops in the brainstem, the critical area connecting your brain to your spinal cord. While these tumors most commonly affect children, they can also occur in adults, and their behavior and outlook vary greatly depending on their location and how fast they grow.

  • 1

    Breast angiosarcoma

    Breast angiosarcoma is a very rare and aggressive cancer that starts in the cells lining blood or lymph vessels in the breast. While it accounts for less than 1% of all breast cancers, people who have received radiation therapy for breast cancer face a higher risk of developing this disease years after treatment.

  • 1

    Breast angiosarcoma metastatic

    Breast angiosarcoma that has spread to other parts of the body is a rare and aggressive form of cancer that presents unique challenges for patients and doctors. Understanding this disease and available treatment options can help patients navigate their journey with greater confidence.

  • 95

    Breast cancer

    Breast cancer happens when cells in the breast tissue grow out of control and form tumors. It is one of the most common cancers affecting women worldwide, though men can develop it too. While a breast cancer diagnosis can be overwhelming, advances in early detection and treatment have led to improved survival rates and better outcomes for many people.

  • 15

    Breast cancer female

    Breast cancer is a condition where cells in breast tissue grow out of control and form tumors. While it is the most common cancer diagnosed in women and the second leading cause of cancer death among women worldwide, advances in early detection and treatment have significantly improved survival rates.

  • 2

    Breast cancer in situ

    Ductal carcinoma in situ is a very early form of breast cancer where abnormal cells are found inside the milk ducts but have not spread into surrounding breast tissue. While not immediately life-threatening, understanding this condition and its treatment options is essential for anyone who receives this diagnosis.

  • 5

    Breast cancer male

    Though rare, breast cancer does occur in men because they have breast tissue that can become cancerous, just like in women. Understanding the signs, knowing your risk factors, and seeking prompt medical attention for any unusual changes can make a crucial difference in outcomes.

  • 34

    Breast cancer metastatic

    Metastatic breast cancer is breast cancer that has spread beyond the breast and nearby lymph nodes to other parts of the body. While there is currently no cure, many people are living longer than ever before thanks to advances in treatment, and it is possible to live well with this disease for many years.

  • 4

    Breast cancer recurrent

    Breast cancer recurrence is when cancer returns after treatment, sometimes months or even years later. While most people treated for breast cancer will not experience a recurrence, understanding the types, symptoms, and treatment options can help you stay informed and prepared.

  • 2

    Breast cancer stage I

    Stage 1 breast cancer is the earliest stage of invasive breast cancer, where the tumor is small and contained within the breast or has spread only minimally to nearby lymph nodes. With treatment, people diagnosed at this stage typically have excellent chances of recovery.

  • 4

    Breast cancer stage II

    Stage 2 breast cancer is an early stage of the disease where cancer cells are either in the breast tissue or nearby lymph nodes, or both. With modern treatments and early detection, many people with stage 2 breast cancer can be successfully treated and go on to live full, healthy lives.

  • 4

    Breast cancer stage III

    Stage 3 breast cancer, also called locally advanced breast cancer, means the cancer has spread beyond the breast tissue to nearby lymph nodes or surrounding structures, but has not reached distant parts of the body.

  • 4

    Breast cancer stage IV

    Stage 4 breast cancer means the cancer has spread beyond the breast to other parts of the body. While there is no cure, many people are living longer than ever before thanks to newer treatments that can control the disease and help maintain quality of life.

  • 1

    Breast conserving surgery

    Breast conserving surgery offers women with early breast cancer a way to remove the tumor while keeping most of their breast tissue intact, achieving survival rates equal to mastectomy when combined with radiation therapy.

  • 3

    Breast neoplasm

    Breast neoplasm, commonly known as breast cancer, is a disease where cells in the breast tissue grow out of control and form tumors. While it most often affects women over 50, it can also occur in younger women and men. With advances in early detection and treatment, many people diagnosed with breast cancer can be successfully treated and go on to live long, healthy lives.

  • 0

    Breast proliferative changes

    Breast proliferative changes represent a group of benign breast conditions where cells in the breast ducts or lobules grow faster than normal. While most of these changes are not cancerous, some types can increase a woman’s risk of developing breast cancer in the future.

  • 11

    Bronchiectasis

    Bronchiectasis is a chronic lung condition where the airways become permanently widened and damaged, making it difficult to clear mucus and leading to frequent infections that can worsen over time.

  • 3

    Bronchiolitis

    Bronchiolitis is a common lung infection that affects babies and young children, causing inflammation and mucus buildup in the tiny airways of the lungs, which can make breathing difficult.

  • 1

    Bronchiolitis obliterans syndrome

    Bronchiolitis obliterans syndrome is a serious lung condition that causes the smallest airways in the lungs to become inflamed, damaged, and scarred, making it difficult to breathe. It most commonly occurs after organ transplants, but can also develop from breathing in harmful chemicals or after severe infections.

  • 1

    Bronchitis

    Bronchitis occurs when the airways in your lungs become inflamed and fill with mucus, causing you to cough persistently. While most cases clear up on their own within a few weeks, understanding the difference between acute and chronic forms can help you manage symptoms and know when to seek medical care.

  • 1

    Bronchopulmonary aspergillosis

    Bronchopulmonary aspergillosis is a lung condition that develops when the immune system overreacts to a common fungus found in soil and decaying plants, causing inflammation that can worsen breathing problems in people with asthma or cystic fibrosis.

  • 8

    Bronchopulmonary dysplasia

    Bronchopulmonary dysplasia is a serious lung condition that primarily affects babies born too early, when their lungs are not yet fully developed. While these tiny infants often need life-saving oxygen therapy and breathing support, this same treatment can damage their delicate lungs over time, leading to long-term breathing difficulties.

  • 1

    Bronchostenosis

    Bronchostenosis is a chronic narrowing of the bronchi, the tubes that carry air into your lungs. This narrowing can make breathing difficult and lead to repeated lung infections, requiring ongoing medical care and lifestyle adjustments to maintain quality of life.

  • 1

    Bulbospinal muscular atrophy congenital

    Bulbospinal muscular atrophy is a rare genetic condition that primarily affects adult men, causing slow but steady muscle weakness that develops over decades.

  • 3

    Burkitt’s lymphoma

    Burkitt’s lymphoma is a rare but fast-growing cancer that develops in the body’s infection-fighting system. Though it can be life-threatening because of how quickly it spreads, most people respond well to treatment and can go into long-term remission when diagnosed and treated right away.

  • 1

    Burning mouth syndrome

    Burning mouth syndrome is a painful condition where your mouth feels like it’s burning, even though there are no visible changes. It most commonly affects women after menopause and can last for months or years, making everyday activities like eating and talking challenging.

  • 1

    Bush-Francis catatonia rating scale

    The Bush-Francis Catatonia Rating Scale is a specialized tool that helps doctors identify and measure the severity of catatonia, a complex condition involving unusual movements and behaviors that affects about 10% of psychiatric patients but often goes undiagnosed.