Explore popular drugs in clinical trials

Check which drugs are currently being frequently studied.

See also our rare diseases glossary and popular diseases list.

Starting by letter

To open the drugs glossary, select a letter from the list below.

Most popular drugs

The list below features the most popular substances currently involved in ongoing clinical trials.

Drug Trials
Pembrolizumab 452
Sodium Chloride 414
Carboplatin 340
Cisplatin 282
Paclitaxel 251
Fluorouracil 232
Oxaliplatin 223
Nivolumab 211
Dexamethasone 205
Rituximab 195
Cyclophosphamide 188
Durvalumab 163
Bevacizumab 162
Capecitabine 157
Paracetamol 156
Atezolizumab 147
Docetaxel 128
Prednisone 127
Tocilizumab 125
Prednisolone 122
Gemcitabine 117
Mycophenolate Mofetil 116
Venetoclax 116
Etoposide 115
Pemetrexed 114
Doxorubicin Hydrochloride 110
Infliximab 99
Lenalidomide 98
Semaglutide 92
Ipilimumab 90
Folinic Acid 89
Acetylsalicylic Acid 89
Placebo 85
Paclitaxel Albumin-Bound 84
Cytarabine 79
Daratumumab 79
Methotrexate 78
Calcium Folinate 78
Fludarabine Phosphate 77
Dapagliflozin 73
Bortezomib 72
Letrozole 72
Olaparib 70
Gemcitabine Hydrochloride 69
Obinutuzumab 68
Azacitidine 66
Trastuzumab 65
Lenvatinib 65
Cetuximab 64
Tacrolimus 63
Fulvestrant 63
Irinotecan 61
Methylprednisolone 60
Irinotecan Hydrochloride Trihydrate 59
Temozolomide 59
Cemiplimab 57
Vincristine Sulfate 57
Trastuzumab Deruxtecan 54
Apixaban 52
Enzalutamide 51
Lidocaine Hydrochloride Monohydrate 50
Betamethasone Sodium Phosphate 50
Amoxicillin 49
Dexamethasone Sodium Phosphate 49
Codeine Phosphate 49
Lidocaine Hydrochloride 47
Buclizine Hydrochloride 47
Exemestane 46
Hydrocortisone 46
Empagliflozin 46
Potassium Chloride 45
Ribociclib 45
Anastrozole 45
Adalimumab 45
Doxorubicin 43
Pomalidomide 43
Pertuzumab 43
Oxygen 42
Clopidogrel 42
Clavulanic Acid 42
Tenofovir Alafenamide 42
Ruxolitinib 41
Rivaroxaban 41
Ibrutinib 41
Sulfamethoxazole 40
Ropivacaine Hydrochloride 40
Abemaciclib 40
Trimethoprim 40
Bendamustine Hydrochloride 40
Atorvastatin 40
Metformin Hydrochloride 40
Propofol 39
Cyclophosphamide Monohydrate 39
Carfilzomib 39
Ifosfamide 38
Pemetrexed Disodium 38
Vinorelbine 38
Emtricitabine 38
Palbociclib 38
Linezolid 38

New drugs in trials

The list below features the new substances involved to ongoing clinical trials.

#1 VMX-C001

Clinical trials are studying VMX-C001 in people who take a Factor Xa direct oral anticoagulant and need urgent surgery or another high-bleeding-risk procedure.

2 months ago
#2 LIPASE

Clinical trials are investigating LIPASE, including a new lipase product compared with pancrelipase.

2 months ago
#3 TRIACYLGLYCEROL LIPASE

Clinical trials of TRIACYLGLYCEROL LIPASE are studying a new lipase treatment in adults with exocrine pancreatic insufficiency.

2 months ago
#4 IMA401

Clinical trials are investigating IMA401 in patients with recurrent and/or refractory solid tumors.

2 months ago
#5 ALLERGEN EXTRACTS

Clinical trials are studying BLOMIA TROPICALIS POLYMERIZED EXTRACT as part of a vaccine for dust mite and Blomia tropicalis allergy.

2 months ago
#6 AUR200

Clinical trials are investigating AUR200 in people with generalized myasthenia gravis.

2 months ago

Drugs starting by l

  • Ly3473329

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    Clinical trials are studying Ly3473329 in adults with elevated lipoprotein(a), also called Lp(a), who are at high risk for cardiovascular events. These trials mainly look at safety and how well the treatment works. The main study in the data is a Phase 2 trial in adult participants.

  • Ly3484356

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    Clinical trials are studying Ly3484356 in breast cancer, including early and advanced disease. These studies aim to evaluate how well it works compared with standard endocrine therapy, and they focus on patients with ER-positive, HER2-negative breast cancer.

  • LY3537021

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    Clinical trials are investigating LY3537021 in adults with cancer who have nausea and vomiting caused by chemotherapy. These studies look at how well LY3537021 works, along with standard anti-nausea treatments, and whether it is safe and effective in this setting.

  • LY3537031

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    Clinical trials are investigating LY3537031 in adults with alcohol use disorder and uncontrolled moderate to severe asthma. These studies aim to check whether the treatment works better than placebo and to measure safety, response, and longer-term effects in different patient groups.

  • Ly3537982

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    Clinical trials are studying Ly3537982 in people with KRAS G12C-mutant cancers, especially non-small cell lung cancer and other advanced solid tumors. These studies look at safety, dose, and how well Ly3537982 works alone or with other cancer treatments. The target groups include people with advanced, resected, or unresectable disease.

  • Ly3541860

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    Clinical trials are studying Ly3541860 in adults with relapsing multiple sclerosis. These trials are designed to evaluate how well it works and to measure safety-related outcomes through MRI brain scans and other study checks. The available trial data focus on people with relapsing MS.

  • Ly3556050

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    Clinical trials are studying Ly3556050 in adults with diabetic peripheral neuropathic pain. These studies aim to see whether it can reduce pain better than placebo and measure changes in pain scores over time. The trial data shown here focuses on adults with diabetic peripheral neuropathy in a Phase 2 study.

  • Ly3819469 Sodium

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    LY3819469 Sodium, also known as Lepodisiran, is an investigational drug currently being studied in clinical trials for its potential to treat lipoprotein disorders, particularly in patients with elevated levels of Lipoprotein(a) [Lp(a)]. This article provides an overview of the ongoing research, including the drug’s mechanism of action, target population, and potential benefits in reducing cardiovascular risks associated with high Lp(a) levels.

  • LY3841136 SODIUM

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    Clinical trials are studying LY3841136 SODIUM, also called eloralintide, in people with obesity or overweight and related health problems. These studies look at whether it helps with body weight and, in some trials, sleep apnea or knee pain from osteoarthritis. Most trials are Phase 3 studies in adults.

  • LY3848575

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    Clinical trials are investigating LY3848575 in people with painful distal sensory polyneuropathy, a type of nerve damage that can cause pain. The main goal is to see whether LY3848575 can reduce pain better than placebo and to measure safety and other study results.

  • Ly3871801

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    Clinical trials are studying Ly3871801 in adults with rheumatoid arthritis. These studies are looking at whether it can improve disease activity and help more people reach meaningful treatment responses. The main focus is on efficacy, with placebo used for comparison.

  • Ly4100511

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    Clinical trials are studying Ly4100511 in adults with moderate-to-severe plaque psoriasis. The main goal is to compare different dose regimens with placebo and measure how well the treatment works and how many people improve. These studies help show whether Ly4100511 may be useful for this skin condition.

  • LY4170156

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    Clinical trials are investigating LY4170156, also called Sofetabart Mipitecan, in people with ovarian cancer and related cancers. This article explains what the trials are studying, who may join, and how the studies measure benefit and safety. The main goal is to compare LY4170156-based treatment with standard treatment options in different ovarian cancer groups.

  • Lymecycline

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    Clinical trials investigating Lymecycline are studying how it performs in patient groups with acne and hidradenitis suppurativa. These studies look at treatment results and compare Lymecycline with other therapies or standard care. The trials include people with moderate acne and patients with Hurley stage 2 active hidradenitis suppurativa.

  • LYSERGIDE

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    Clinical trials are investigating LYSERGIDE in different patient groups to see whether it can help with symptoms and whether it is safe and effective in study settings. The trials in this article include adults with generalized anxiety disorder, chronic cluster headache, and attention deficit hyperactivity disorder (ADHD).

  • Lysine Acetate

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    Clinical trials investigating Lysine Acetate are studying how it is used in different surgical and kidney disease settings. These trials look at outcomes such as muscle loss, infections, and muscle mass, and they mainly include adults after major surgery or with advanced chronic kidney disease.

  • Lysine Aspirin

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    Clinical trials investigating Lysine Aspirin are studying its use in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA). The main goal is to learn whether a precision-medicine approach can improve symptoms and quality of life. These trials focus on adults with MINOCA and measure outcomes such as angina status and patient-reported quality of life.

  • Lysine Hydrochloride

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    Clinical trials listed here are investigating Lysine Hydrochloride as part of treatment plans in several studies. The trials look at safety, dose finding, and treatment benefit in groups such as children with neuroblastoma, adults with GEP-NETs, and patients with lung cancer or hemodialysis-related muscle changes.