Explore popular drugs in clinical trials

Check which drugs are currently being frequently studied.

See also our rare diseases glossary and popular diseases list.

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To open the drugs glossary, select a letter from the list below.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All drugs

Most popular drugs

The list below features the most popular substances currently involved in ongoing clinical trials.

Drug	Trials
Pembrolizumab	454
Sodium Chloride	416
Carboplatin	339
Cisplatin	282
Paclitaxel	251
Fluorouracil	231
Oxaliplatin	222
Nivolumab	211
Dexamethasone	206
Rituximab	196
Cyclophosphamide	188
Durvalumab	164
Bevacizumab	161
Capecitabine	157
Paracetamol	156
Atezolizumab	147
Docetaxel	129
Prednisone	127
Tocilizumab	125
Prednisolone	123
Mycophenolate Mofetil	116
Venetoclax	116
Gemcitabine	116
Pemetrexed	115
Etoposide	115
Doxorubicin Hydrochloride	110
Infliximab	99
Lenalidomide	98
Semaglutide	92
Ipilimumab	90
Acetylsalicylic Acid	90
Folinic Acid	89
Placebo	85
Paclitaxel Albumin-Bound	83
Daratumumab	80
Cytarabine	79
Methotrexate	78
Calcium Folinate	77
Fludarabine Phosphate	77
Letrozole	73
Dapagliflozin	73
Bortezomib	72
Olaparib	70
Gemcitabine Hydrochloride	69
Obinutuzumab	68
Azacitidine	66
Trastuzumab	65
Lenvatinib	65
Cetuximab	65
Fulvestrant	64
Tacrolimus	63
Irinotecan Hydrochloride Trihydrate	60
Irinotecan	60
Methylprednisolone	59
Temozolomide	59
Cemiplimab	57
Vincristine Sulfate	57
Trastuzumab Deruxtecan	54
Apixaban	52
Enzalutamide	51
Lidocaine Hydrochloride Monohydrate	51
Betamethasone Sodium Phosphate	50
Amoxicillin	49
Dexamethasone Sodium Phosphate	49
Codeine Phosphate	49
Exemestane	47
Buclizine Hydrochloride	47
Lidocaine Hydrochloride	47
Hydrocortisone	46
Anastrozole	46
Empagliflozin	46
Adalimumab	46
Potassium Chloride	45
Ribociclib	45
Pomalidomide	43
Clavulanic Acid	43
Pertuzumab	43
Oxygen	43
Doxorubicin	43
Tenofovir Alafenamide	42
Clopidogrel	42
Trimethoprim	41
Rivaroxaban	41
Ibrutinib	41
Sulfamethoxazole	41
Ruxolitinib	41
Ropivacaine Hydrochloride	40
Abemaciclib	40
Bendamustine Hydrochloride	40
Atorvastatin	40
Metformin Hydrochloride	40
Linezolid	39
Carfilzomib	39
Propofol	39
Cyclophosphamide Monohydrate	39
Palbociclib	38
Ciprofloxacin	38
Dexamethasone Phosphate	38
Ifosfamide	38
Pemetrexed Disodium	38

New drugs in trials

The list below features the new substances involved to ongoing clinical trials.

#1 VMX-C001

Clinical trials are studying VMX-C001 in people who take a Factor Xa direct oral anticoagulant and need urgent surgery or another high-bleeding-risk procedure.

2 months ago

#2 LIPASE

Clinical trials are investigating LIPASE, including a new lipase product compared with pancrelipase.

2 months ago

#3 TRIACYLGLYCEROL LIPASE

Clinical trials of TRIACYLGLYCEROL LIPASE are studying a new lipase treatment in adults with exocrine pancreatic insufficiency.

2 months ago

#4 IMA401

Clinical trials are investigating IMA401 in patients with recurrent and/or refractory solid tumors.

2 months ago

#5 ALLERGEN EXTRACTS

Clinical trials are studying BLOMIA TROPICALIS POLYMERIZED EXTRACT as part of a vaccine for dust mite and Blomia tropicalis allergy.

2 months ago

#6 AUR200

Clinical trials are investigating AUR200 in people with generalized myasthenia gravis.

2 months ago

Drugs starting by k

1
Kan-101

Diseases, Immune System Diseases

KAN-101 is an investigational drug currently being studied in clinical trials for the treatment of Celiac Disease (CeD). These trials aim to evaluate the safety, tolerability, and efficacy of KAN-101 in patients with CeD who are on a gluten-free diet. The studies involve both single and multiple dose administrations of KAN-101 through intravenous infusion, comparing its effects to a placebo. Researchers are particularly interested in understanding how KAN-101 may protect against gluten-induced changes in the small intestine and its overall impact on patients with Celiac Disease.

Related diseases and areas:
- Coeliac disease
1
Kbp-336

Diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases
A new clinical trial is underway to assess the effectiveness and safety of KBP-336, a potential treatment for individuals living with obesity and knee osteoarthritis. This study aims to determine if KBP-336 can reduce knee pain and promote weight loss in this population. The trial will compare KBP-336 to a placebo over a 6-month period, focusing on pain reduction, weight loss, and overall quality of life improvements.

Related diseases and areas:
- Obesity
1
Kd050

Diseases, Neoplasms
A groundbreaking clinical trial is underway to evaluate the safety and effectiveness of KD050, also known as SAR445877, in treating advanced solid tumors. This Phase 1/2 study aims to determine the optimal dosage and assess the drug’s potential as both a standalone treatment and in combination with other cancer therapies. The trial focuses on various types of advanced cancers, including non-small cell lung cancer, hepatocellular carcinoma, and gastric cancer.

Related diseases and areas:
- Neoplasm
13
Ketamine

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Diseases, Mental Disorders, Nervous System Diseases, Psychiatry and Psychology, Therapeutics
This article examines the use of ketamine in various clinical trials, focusing on its potential applications in pain management, anesthesia, and treatment of depression. Ketamine, a versatile drug with both anesthetic and analgesic properties, is being studied in different forms and dosages to evaluate its efficacy and safety in treating conditions such as complex regional pain syndrome, postoperative pain, and major depressive disorder.

Related diseases and areas:
20
Ketamine Hydrochloride

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Cardiovascular Diseases, Diseases, Health Care, Health Care Quality, Access, and Evaluation, Mental Disorders, Nervous System Diseases, Psychiatry and Psychology, Psychological Phenomena, Respiratory Tract Diseases, Therapeutics
Ketamine Hydrochloride, a versatile anesthetic agent, is being investigated in various clinical trials for its potential therapeutic benefits beyond its traditional use. These studies explore its applications in managing complex regional pain syndrome (CRPS), providing cerebral protection in children undergoing heart surgery, and even as a treatment for anorexia nervosa. This article delves into the ongoing research and potential of Ketamine Hydrochloride in different medical fields.

Related diseases and areas:
3
Keto-Isoleucine Calcium

Diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases
This article discusses a clinical trial investigating the use of Keto-Isoleucine Calcium, a component of the drug Ketosteril, in preventing muscle loss in patients with nephrotic syndrome. The study aims to assess the efficacy and safety of ketoanalogues of essential amino acids in protecting against protein-energy wasting, a common complication in nephrotic syndrome patients.

Related diseases and areas:
- Chronic kidney disease
- Nephrotic syndrome
3
Keto-Leucine Calcium

Diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases
This article discusses a clinical trial investigating the use of Keto-Leucine Calcium, a component of the drug Ketosteril, in preventing muscle loss in patients with nephrotic syndrome. The study aims to evaluate the efficacy, safety, and tolerability of this treatment in a new clinical indication, focusing on its potential to prevent protein-energy wasting in individuals with moderate to severe nephrotic syndrome.

Related diseases and areas:
- Nephrotic syndrome
- Chronic kidney disease
3
Keto-Valine Calcium

Diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases
This article discusses the clinical trials investigating the use of Keto-Valine Calcium, a component of the drug Ketosteril, in preventing muscle loss in patients with nephrotic syndrome. The trials aim to assess the efficacy, safety, and tolerability of this treatment in a new clinical indication, focusing on its potential to prevent protein-energy wasting in individuals with moderate to severe nephrotic syndrome.

Related diseases and areas:
- Nephrotic syndrome
- Chronic kidney disease
7
Ketoprofen

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Cardiovascular Diseases, Diseases, Musculoskeletal Diseases, Pathological Conditions, Signs and Symptoms, Respiratory Tract Diseases, Surgical Procedures, Operative, Therapeutics
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that has been studied in various clinical trials for its effectiveness in managing pain and other medical conditions. This article examines the use of ketoprofen in different formulations and dosages across several clinical studies, highlighting its potential benefits and applications in healthcare.

Related diseases and areas:
1
Ketoprofen Lysine

Diseases, Musculoskeletal Diseases
Ketoprofen Lysine, a nonsteroidal anti-inflammatory drug (NSAID), has been the subject of several clinical trials to evaluate its effectiveness and safety in various formulations and combinations. These studies aim to understand its pharmacokinetics, bioequivalence, and potential benefits in treating conditions such as pharyngitis and pain management. The trials also explore new delivery methods and combinations with other drugs to enhance its therapeutic effects.

Related diseases and areas:
- Back pain
1
KETOROLAC

Diseases, Neoplasms
Ketorolac tromethamine is a potent non-steroidal anti-inflammatory drug (NSAID) that has been studied extensively in various clinical settings for pain management. Unlike opioids, ketorolac provides effective pain relief without the risks of dependence or respiratory depression. This article explores how ketorolac is being used in clinical trials across different medical specialties, including ophthalmology, obstetrics, orthopedics, and emergency medicine. We’ll examine different formulations (intravenous, intranasal, and topical), dosing strategies, and how this medication compares to other pain management approaches.

Related diseases and areas:
- Hormone receptor positive b…
3
KETOROLAC TROMETAMOL

Digestive System Diseases, Diseases, Eye Diseases, Neoplasms
Ketorolac Tromethamine is a potent non-steroidal anti-inflammatory drug (NSAID) that has been studied extensively in various clinical settings. This medication works primarily by inhibiting the synthesis of prostaglandins, which are key mediators of pain and inflammation in the body. Clinical trials have explored multiple administration routes for ketorolac, including intravenous, intranasal, topical, and oral formulations, demonstrating its versatility across different patient populations and conditions. From acute pain management in emergency settings to postoperative care and chronic conditions, ketorolac offers a non-opioid alternative that may help reduce reliance on potentially addictive pain medications while providing effective relief. This article summarizes the key findings from recent clinical trials investigating the efficacy, safety, and optimal dosing of ketorolac tromethamine in various clinical applications.

Related diseases and areas:
- Appendicitis
1
Ketotifen Hydrogen Fumarate

Diseases, Eye Diseases, Otorhinolaryngologic Diseases
This article discusses a Phase III clinical trial investigating the use of Ketotifen Hydrogen Fumarate eye drops for treating seasonal allergic conjunctivitis (SAC). The study aims to evaluate the efficacy and safety of a 0.5 mg/ml Ketotifen ophthalmic solution compared to a vehicle (placebo) and an active control (Ketoftil) in managing SAC symptoms. This multicentre, randomized, double-blind trial focuses on assessing various aspects of eye discomfort and inflammation associated with seasonal allergies.

Related diseases and areas:
- Conjunctivitis allergic
1
Kk8123

Diseases, Nutritional and Metabolic Diseases
A groundbreaking clinical trial is underway to evaluate the potential of KK8123, a novel drug designed to treat X-linked Hypophosphatemia (XLH). This first-in-human study aims to assess the safety, tolerability, and effectiveness of KK8123 in adult patients with XLH. The trial consists of multiple phases, including dose escalation and an optional extension period, providing valuable insights into this innovative treatment approach.

Related diseases and areas:
- Hereditary hypophosphataemi…
1
Kpl-404

Diseases, Eye Diseases, Immune System Diseases, Musculoskeletal Diseases, Skin and Connective Tissue Diseases, Stomatognathic Diseases
KPL-404, also known as abiprubart, is a humanized monoclonal antibody being studied in clinical trials for its potential in treating rheumatoid arthritis. These trials aim to assess the safety, effectiveness, and how the body processes this new drug. The studies involve both healthy volunteers and patients with moderate to severe rheumatoid arthritis who haven’t responded well to other treatments.

Related diseases and areas:
- Sjogren’s syndrome
5
Kyv-101

Diseases, Immune System Diseases, Musculoskeletal Diseases, Nervous System Diseases
KYV-101, a fully-human anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, is currently being studied in clinical trials for various autoimmune diseases. These trials aim to assess the safety, tolerability, and clinical effectiveness of KYV-101 in treating conditions such as idiopathic inflammatory myopathies, diffuse cutaneous systemic sclerosis, systemic lupus erythematosus with nephritis, and ANCA-associated vasculitis. The studies involve administering a single dose of KYV-101 to participants and monitoring their progress over an extended period.

Related diseases and areas:

Explore popular drugs in clinical trials

Starting by letter

Most popular drugs

New drugs in trials

#1 VMX-C001

#2 LIPASE

#3 TRIACYLGLYCEROL LIPASE

#4 IMA401

#5 ALLERGEN EXTRACTS

#6 AUR200

Drugs starting by k

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