Bulgaria

Study of mirikizumab and tirzepatide for adults with moderate to severe Crohn’s disease who are overweight or obese

Recruiting

3 1
Investigated Drugs:
- Mirikizumab
- Tirzepatide
+9
Study of MK-1084 and Pembrolizumab for First-Line Treatment in Patients with Metastatic Non-Small Cell Lung Cancer with KRAS G12C Mutation and High PD-L1 Levels

Recruiting

3 1 1
Investigated Drugs:
- Mk-1084
- Pembrolizumab
+4
Efficacy and safety of oral semaglutide for weight loss in adults with overweight or obesity

Recruiting

3 1 1
Investigated Drugs:
- Semaglutide
+3
Efficacy and Safety of Depemokimab for Early Intervention in Adults and Adolescents with Type 2 Asthma at Risk of Exacerbations

Recruiting

3 1 1
Investigated Drugs:
- Depemokimab
+3
A Phase 3 Study of Enpatoran to Treat Active Cutaneous Lupus in Patients With or Without Systemic Disease

Recruiting

3 1
Investigated Diseases:
+4
A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis

Recruiting

3 1

+15

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Abdominal infection Acquired ATTR amyloidosis Acquired C1 inhibitor deficiency Acromegaly Acute coronary syndrome Acute haemorrhagic ulcerative colitis Acute hepatic failure Acute lymphocytic leukaemia Acute myeloid leukaemia Acute myocardial infarction Acute respiratory distress syndrome Acute respiratory failure Adenomyosis Adrenogenital syndrome Alcoholic liver disease Alopecia areata Anaemia Anaemia of chronic disease Anal incontinence Angina pectoris Anhedonia Ankylosing spondylitis Arteriosclerosis Arteriovenous graft thrombosis Asthma Asthmatic crisis Atrial fibrillation Axial spondyloarthritis B-cell lymphoma B-cell small lymphocytic lymphoma Bacterial infection Bipolar disorder Bipolar I disorder Bladder cancer Breast cancer Breast cancer metastatic Bronchiectasis Cachexia Cardiac ablation Cardiac amyloidosis Cardiac failure Cardiac failure chronic Cardiovascular disorder Central nervous system melanoma Cerebrovascular accident prophylaxis Cervix carcinoma recurrent Cholangiocarcinoma Cholestatic pruritus Chronic cutaneous lupus erythematosus Chronic hepatitis Chronic hepatitis B Chronic inflammatory demyelinating polyradiculoneuropathy Chronic kidney disease Chronic lymphocytic leukaemia Chronic lymphocytic leukaemia recurrent Chronic myeloid leukaemia Chronic myelomonocytic leukaemia Chronic obstructive pulmonary disease Chronic rhinosinusitis with nasal polyps Chronic sinusitis Chronic spontaneous urticaria Clear cell renal cell carcinoma Clostridium difficile infection Coagulation factor X level Cognitive disorder Cold urticaria Colitis ulcerative Colorectal adenocarcinoma Colorectal cancer Colorectal cancer metastatic Conjunctivitis allergic Connective tissue disorder Constipation COVID-19 Crohn's disease Cushing's syndrome Cutaneous lupus erythematosus Deep vein thrombosis Dementia Alzheimer's type Dementia of the Alzheimer's type with delusions Dementia with Lewy bodies Dermatitis Dermatitis atopic Dermatomyositis Diabetic foot infection Diabetic neuropathy Diabetic retinal oedema Diffuse large B-cell lymphoma Dilated cardiomyopathy Dry age-related macular degeneration Dry eye Duchenne muscular dystrophy Dyslipidaemia Eczema nummular EGFR gene mutation Embolism Embolism venous Endocrine ophthalmopathy Endometrial adenocarcinoma Endometrial cancer Endometriosis Epilepsy Epstein-Barr virus associated lymphoma Erosive oesophagitis Ex-tobacco user Eyelid ptosis Factor IX deficiency Factor VIII deficiency Fallopian tube cancer Familial hypertriglyceridaemia Follicle centre lymphoma follicular grade I, II - III Follicular lymphoma Gastric cancer Gastrointestinal cancer metastatic Gastrointestinal melanoma Gastrooesophageal reflux disease Generalised anxiety disorder Generalised tonic-clonic seizure Genital herpes simplex Gout Haematological infection Haemophilia A with anti factor VIII Haemophilia A without inhibitors Haemophilia B without inhibitors Hepatic cirrhosis Hepatic encephalopathy Hepatitis B Hepatitis D Hepatitis viral Hepatocellular carcinoma HER2 positive breast cancer Hereditary angioedema Hereditary angioedema with C1 esterase inhibitor deficiency Hereditary neuropathic amyloidosis Hidradenitis High-grade B-cell lymphoma Hormone receptor positive breast cancer Hormone receptor positive HER2 negative breast cancer Hormone-dependent prostate cancer Hormone-refractory prostate cancer Huntington's disease Hypercholesterolaemia Hyperchylomicronaemia Hyperinsulinaemic hypoglycaemia Hyperinsulinism Hyperparathyroidism secondary Hypertension Hypertriglyceridaemia Hypertrophic cardiomyopathy Idiopathic inflammatory myopathy Idiopathic pulmonary fibrosis IgA nephropathy Immune thrombocytopenia Inborn error of metabolism Indolent systemic mastocytosis Infection prophylaxis Influenza Influenza immunisation Insomnia Iridocyclitis Iron deficiency Ischaemic stroke Juvenile idiopathic arthritis Left ventricular dysfunction Lung adenocarcinoma Lupus nephritis Macular oedema Magnetic resonance imaging Major depression Malignant melanoma Malignant melanoma of eyelid Malignant melanoma stage III Malignant melanoma stage IV Mania Marginal zone lymphoma Melanoma recurrent Metabolic dysfunction-associated liver disease Metabolic dysfunction-associated steatohepatitis Metapneumovirus infection Metastatic malignant melanoma Migraine Multiple sclerosis Multiple sclerosis relapse Muscle spasticity Myasthenia gravis Myelodysplastic syndrome Myelofibrosis Myeloproliferative neoplasm Neoplasm Neoplasm malignant Neovascular age-related macular degeneration Nephrogenic anaemia Nervous system disorder Netherton's syndrome Neuralgia Neurodermatitis Neuroendocrine carcinoma Neuropathy peripheral Non-alcoholic steatohepatitis Non-Hodgkin's lymphoma Non-small cell lung cancer Non-small cell lung cancer metastatic Non-small cell lung cancer recurrent Non-small cell lung cancer stage III Non-small cell lung cancer stage IIIA Non-small cell lung cancer stage IIIB Non-small cell lung cancer stage IV Noonan syndrome Obesity Open angle glaucoma Osteoarthritis Osteoporosis Osteoporosis postmenopausal Ovarian cancer Ovarian epithelial cancer Overweight Pain Pancreatic carcinoma metastatic Pancreatic failure Paranasal sinus inflammation Parkinson's disease Partial seizures Pemphigoid Philadelphia positive acute lymphocytic leukaemia Pituitary-dependent Cushing's syndrome Plasma cell myeloma Pneumonia Polycythaemia vera Polymyositis Porphyria non-acute Post herpetic neuralgia Postoperative analgesia Pre-eclampsia Primary biliary cholangitis Primary myelofibrosis Primary progressive multiple sclerosis Progressive multiple sclerosis Progressive relapsing multiple sclerosis Progressive supranuclear palsy Prostate cancer Prostate cancer metastatic Proteinuria Psoriasis Psoriatic arthropathy Psychotic disorder Pulmonary arterial hypertension Pulmonary hypertension Pyelonephritis acute Relapsing multiple sclerosis Relapsing-remitting multiple sclerosis Renal cell carcinoma Respiratory syncytial virus infection Retinal vein occlusion Retinopathy of prematurity Rheumatoid arthritis Rhinitis allergic Schizophrenia Secondary progressive multiple sclerosis Seizure Sepsis Short stature Sinusitis noninfective Sjogren's syndrome Skin bacterial infection Small cell lung cancer Small cell lung cancer extensive stage Small cell lung cancer limited stage Small cell lung cancer recurrent Small for dates baby Squamous cell carcinoma of head and neck Squamous cell carcinoma of lung Squamous cell carcinoma of skin Still's disease Subacute cutaneous lupus erythematosus Systemic candida Systemic lupus erythematosus Systemic scleroderma Thalassaemia Thrombocytopenia Thrombolysis Thrombosis prophylaxis Tourette's disorder Transient ischaemic attack Transitional cell cancer of the renal pelvis and ureter Transitional cell carcinoma Triple negative breast cancer Turner's syndrome Type 2 diabetes mellitus Type IIa hyperlipidaemia Urea cycle disorder Urinary tract infection Varicella Vernal keratoconjunctivitis Vitiligo Warm autoimmune haemolytic anaemia

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