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Metabolic dysfunction-associated liver disease

  • N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD

    Recruiting

    3 1
    Investigated Diseases:
    • Metabolic dysfunction-associated liver disease
    Investigated Drugs:
    • Ly3437943 Sodium
    • Tirzepatide
    Austria Belgium Bulgaria Czechia France Germany +9

  • Study of Pioglitazone and Metformin combination treatment for patients with Metabolic Associated Fatty Liver Disease and prediabetes

    Recruiting

    3 1 1 1
    Investigated Diseases:
    • Glucose tolerance impaired
    • Metabolic dysfunction-associated liver disease
    Investigated Drugs:
    • Pioglitazone
    • Metformin Hydrochloride
    Spain

  • Study on the Effects of Pegozafermin for Patients with Nonalcoholic Steatohepatitis (NASH) and Fibrosis

    Recruiting

    3 1
    Investigated Diseases:
    • Metabolic dysfunction-associated liver disease
    Investigated Drugs:
    • Bio89-100
    Austria Belgium Bulgaria Czechia France Germany +4

  • Comparing liquid versus capsule forms of phosphatidylcholine in patients with alcoholic liver disease, chronic hepatitis B, and metabolic liver disease

    Not recruiting

    3 1 1
    Investigated Diseases:
    • Alcoholic liver disease
    • Metabolic dysfunction-associated liver disease
    Bulgaria Germany Poland

  • Study on GSK4532990 for Adults with Nonalcoholic Steatohepatitis (NASH)

    Not recruiting

    2 1
    Investigated Diseases:
    • Metabolic dysfunction-associated liver disease
    Investigated Drugs:
    • Gsk4532990A
    Belgium France Greece Italy Spain

  • Study on the Effects of Semaglutide on Insulin Resistance and Lipid Metabolism in Women with Obesity and Non-Alcoholic Fatty Liver Disease

    Not recruiting

    3 1 1 1
    Investigated Diseases:
    • Metabolic dysfunction-associated liver disease
    • Obesity
    Investigated Drugs:
    • Semaglutide
    Denmark
1 2
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European Clinical Trials Information Network

The European Clinical Trials Information Network is transforming access to clinical trial information for patients across Europe. By overcoming language barriers, our platform allows everyone, regardless of their native language, to easily find relevant and comprehensible clinical trial data. This innovative service connects patients to cutting-edge treatments, creating a unified European community where health and progress transcend borders.

This service is not affiliated with the European Commission, the EMA, or the official CTIS system. Most information comes from publicly available international clinical-trial registries, supplemented by data from academic centres, national regulators, and commercial sponsors. We aim to keep all content accurate and up to date.

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