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Systemic scleroderma

  • Phase 2 Study of Nemolizumab for Skin Thickening in Adults with Systemic Sclerosis

    Recruiting

    2 1 1 1
    Investigated Drugs:
    • Nemolizumab
    Bulgaria Croatia France Greece Italy Poland +1

  • Using 68Ga-FAPI-46 imaging to detect fibrosis in patients with inflammatory diseases such as Crohn’s disease, ulcerative colitis, systemic sclerosis, and lung fibrosis.

    Recruiting

    2 1 1
    Investigated Diseases:
    • Idiopathic inflammatory myopathy
    • Interstitial lung disease
    • Systemic scleroderma
    Investigated Drugs:
    • (S)-2,2′,2”-(10-(2-(4-(3-((4-(2-(2-Cyano-4,4-Difluoropyrrolidin-1-Yl)-2-Oxoethylcarbamoyl)-Quinolin-6-Yl)(Methyl)Amino)-Propyl)Piperazin-1-Yl)-2-Oxoethyl)-68Ga-[1,4,7,10]-Tetraazacyclododecane-1,4,7-Triyl)Triacetate
    The Netherlands

  • A Study of Cizutamig for Patients with Severe Autoimmune Inflammatory Diseases That Did Not Respond to Previous Treatments

    Recruiting

    1 1 1
    Investigated Diseases:
    • Idiopathic inflammatory myopathy
    • Sjogren’s syndrome
    • Rheumatoid arthritis
    Germany

  • A Study of Idecabtagene Vicleucel CAR-T Cell Therapy for Patients with Autoimmune Diseases That Did Not Respond to B Cell Removal Treatment

    Recruiting

    1 1 1 1
    Investigated Diseases:
    • Idiopathic inflammatory myopathy
    • Sjogren’s syndrome
    • Systemic scleroderma
    Investigated Drugs:
    • Idecabtagene Vicleucel
    Germany

  • A Study Testing Anti-CD19 CAR T-Cell Therapy in Patients with Systemic Sclerosis Who Did Not Respond to Immunosuppressive Drugs

    Recruiting

    2 1 1
    Investigated Diseases:
    • Systemic scleroderma
    Investigated Drugs:
    • Autologous T-Cells Transduced With Lentiviral Vector Expressing A Chimeric Antigen Receptor Directed Against Cd19
    France

  • Study of AlloNK and rituximab with cyclophosphamide and fludarabine in adults with relapsing rheumatoid arthritis, inflammatory myopathies, systemic sclerosis, or Sjögren’s disease

    Recruiting

    2 1 1 1
    Investigated Diseases:
    • Sjogren’s syndrome
    • Rheumatoid arthritis
    • Systemic scleroderma
    Investigated Drugs:
    • ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED NATURAL KILLER CELLS, EX VIVO EXPANDED
    • Fludarabine Phosphate
    • Cyclophosphamide
    Bulgaria France Germany Italy Poland Portugal +2
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The European Clinical Trials Information Network is transforming access to clinical trial information for patients across Europe. By overcoming language barriers, our platform allows everyone, regardless of their native language, to easily find relevant and comprehensible clinical trial data. This innovative service connects patients to cutting-edge treatments, creating a unified European community where health and progress transcend borders.

This service is not affiliated with the European Commission, the EMA, or the official CTIS system. Most information comes from publicly available international clinical-trial registries, supplemented by data from academic centres, national regulators, and commercial sponsors. We aim to keep all content accurate and up to date.

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