Finland

Efficacy and safety of lunsekimig in adults with inadequately controlled eosinophilic COPD: a randomized, double‑blind, placebo‑controlled trial

Recruiting

4 1
Investigated Diseases:
- Chronic obstructive pulmonary disease
Investigated Drugs:
- LUNSEKIMIG
+7
Long‑Term Safety, Tolerability and Efficacy of Azetukalner in Patients with Major Depressive Disorder

Recruiting

3 1 1
Investigated Diseases:
- Major depression
Investigated Drugs:
- Azetukalner
Venetoclax added to fludarabine, cytarabine and gemtuzumab ozogamicin (drug combination) in children with relapsed acute myeloid leukemia

Recruiting

3 1 1 1
Investigated Diseases:
- Acute myeloid leukaemia
Investigated Drugs:
+8
Orelabrutinib in Patients with Primary Progressive Multiple Sclerosis

Recruiting

3 1
Investigated Diseases:
- Primary progressive multiple sclerosis
+14
Pumitamig Versus Pembrolizumab in Patients With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%

Recruiting

3 1 1 1
Investigated Diseases:
- Non-small cell lung cancer
- Non-small cell lung cancer metastatic
Investigated Drugs:
- Pembrolizumab
+10
Obrixtamig, Carboplatin, and Etoposide for First-Line Treatment of Advanced Extrapulmonary Neuroendocrine Carcinoma in DLL3-Positive Patients

Recruiting

3 1 1 1
Investigated Diseases:
- Neuroendocrine carcinoma
Investigated Drugs:
+8

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Acute lymphocytic leukaemia Acute lymphocytic leukaemia recurrent Acute myeloid leukaemia Acute myeloid leukaemia recurrent Acute myeloid leukaemia refractory Acute myocardial infarction Acute respiratory distress syndrome Adenocarcinoma of colon Allogenic stem cell transplantation Alpha-1 antitrypsin deficiency Amyotrophic lateral sclerosis Analgesic therapy Anaplastic large cell lymphoma T- and null-cell types Aortic valve disease Appendicitis Arteriosclerosis Asthma Atrial fibrillation Atypical teratoid/rhabdoid tumour of CNS Autonomic nervous system imbalance Avian influenza B-cell lymphoma B-cell lymphoma recurrent B-cell lymphoma refractory B-cell small lymphocytic lymphoma B-cell type acute leukaemia Bacterial infection Benign prostatic hyperplasia Beta haemolytic streptococcal infection Bile duct cancer Bladder cancer Bone marrow failure Brain stem glioma Breast cancer Breast cancer metastatic Bronchiectasis Bronchiolitis Bronchopulmonary dysplasia Cardiac failure Cardiovascular disorder Central nervous system lymphoma Central nervous system melanoma Cerebrovascular accident Cerebrovascular accident prophylaxis Cervix carcinoma Cervix carcinoma recurrent Cholangiocarcinoma Cholangitis sclerosing Cholecystitis acute Chronic graft versus host disease Chronic inflammatory demyelinating polyradiculoneuropathy Chronic kidney disease Chronic left ventricular failure Chronic lymphocytic leukaemia Chronic myeloid leukaemia Chronic myelomonocytic leukaemia Chronic obstructive pulmonary disease Chronic rhinosinusitis with nasal polyps Clear cell renal cell carcinoma Coeliac disease Cognitive disorder Colitis ulcerative Colon cancer Colorectal cancer Colorectal cancer metastatic Conjunctivitis allergic Contraception Coronary artery disease Cough COVID-19 Craniocerebral injury Critical illness Crohn's disease Cytomegalovirus immunisation Delirium Dementia Dementia Alzheimer's type Dermatitis atopic Diabetic foot Diffuse large B-cell lymphoma Diffuse large B-cell lymphoma refractory Diphtheria immunisation Ductal adenocarcinoma of pancreas Dupuytren's contracture Dyslipidaemia Ectopic pregnancy EGFR gene mutation Elderly Embolism venous Emphysema Encephalopathy neonatal End stage renal disease Endometrial adenocarcinoma Endometrial cancer Endometrial cancer metastatic Endometrial cancer recurrent Endometrial cancer stage III Endometrial cancer stage IV Endometriosis Eosinophilic oesophagitis Ependymoma Epileptic encephalopathy Epstein-Barr virus associated lymphoma Ewing's sarcoma Ewing's sarcoma metastatic Ewing's sarcoma recurrent Extra-osseous Ewing's sarcoma Extra-osseous Ewing's sarcoma metastatic Extra-osseous Ewing's sarcoma recurrent Fabry's disease Factor VIII deficiency Fallopian tube cancer Familial hypertriglyceridaemia Fibrodysplasia ossificans progressiva Follicle centre lymphoma follicular grade I, II - III Follicle centre lymphoma follicular grade I, II - III recurrent Follicular lymphoma Frostbite Gastric cancer Gastrointestinal carcinoma Gastrointestinal melanoma Gastrointestinal stromal tumour General anaesthesia Generalised anxiety disorder Generalised tonic-clonic seizure Glaucoma Haemorrhage Head and neck cancer Hemiparesis Hepatocellular carcinoma HER2 positive breast cancer Herpes zoster Hidradenitis High-grade B-cell lymphoma Hip arthroplasty HIV infection Hormone receptor positive breast cancer Hormone receptor positive HER2 negative breast cancer Hormone-dependent prostate cancer Hormone-refractory prostate cancer Hot flush Human epidermal growth factor receptor negative Hypercholesterolaemia Hyperchylomicronaemia Hyperkalaemia Hypertension Hypertriglyceridaemia Hypertrophic cardiomyopathy Hypophosphatasia Hysterectomy Idiopathic generalised epilepsy Idiopathic pulmonary fibrosis Immune-mediated myositis Infantile spasms Inflammatory myofibroblastic tumour Influenza Influenza immunisation Inguinal hernia Insomnia Intensive care Interstitial lung disease Intracranial aneurysm Ischaemic stroke Juvenile idiopathic arthritis K-ras gene mutation Kidney transplant rejection Labour pain Laryngeal leukoplakia Laryngitis Left ventricular dysfunction Liposarcoma Lung adenocarcinoma Lung transplant rejection Lyme disease Major depression Malignant glioma Malignant lymphoid neoplasm Malignant melanoma Malignant melanoma of eyelid Malignant melanoma stage III Malignant melanoma stage IV Malignant peritoneal neoplasm Mantle cell lymphoma Mantle cell lymphoma stage II Mantle cell lymphoma stage III Mantle cell lymphoma stage IV Marginal zone lymphoma Mechanical ventilation Medulloblastoma Melanoma recurrent Meningococcal immunisation Meningococcal infection Metabolic syndrome Metapneumovirus infection Metastases to lymph nodes Metastatic malignant melanoma Metastatic renal cell carcinoma Migraine Mitral valve disease Multiple sclerosis Multiple sclerosis relapse Myasthenia gravis Myelodysplastic syndrome Myelodysplastic syndrome transformation Myelodysplastic syndrome with excess blasts Myocardial infarction Myocarditis Narcolepsy Neonatal asphyxia Neoplasm Neoplasm malignant Nephrogenic anaemia Nephropathy Nervous system disorder Netherton's syndrome Neuralgia Neuroblastoma Neurodegenerative disorder Neurodermatitis Neuroendocrine carcinoma Neuromuscular blockade Neuromuscular scoliosis Neurosurgery Non-Hodgkin's lymphoma Non-small cell lung cancer Non-small cell lung cancer metastatic Non-small cell lung cancer stage IV Noonan syndrome Normal tension glaucoma Obesity Ocular myasthenia Oesophageal atresia Oesophageal squamous cell carcinoma Osteoarthritis Osteochondrodysplasia Osteomyelitis Osteosarcoma Otitis media Ovarian cancer Ovarian cancer metastatic Ovarian cancer recurrent Ovarian cancer stage III Ovarian cancer stage IV Ovarian epithelial cancer recurrent Overweight Pancreatic carcinoma Pancreatic carcinoma metastatic Pancreatic neuroendocrine tumour Papillary cystadenoma lymphomatosum Paraganglion neoplasm Partial seizures Peripheral arterial occlusive disease Pertussis immunisation Phaeochromocytoma Plasma cell myeloma Plasma cell myeloma refractory Pneumococcal immunisation Pneumococcal infection Pneumonia respiratory syncytial viral Polycystic ovarian syndrome Post procedural complication Pre-eclampsia Precursor B-lymphoblastic lymphoma recurrent Precursor B-lymphoblastic lymphoma refractory Precursor T-lymphoblastic lymphoma/leukaemia recurrent Precursor T-lymphoblastic lymphoma/leukaemia refractory Primary progressive multiple sclerosis Procedural pain Progressive multiple sclerosis Progressive relapsing multiple sclerosis Prophylaxis Prostate cancer Prostate cancer metastatic Prostate cancer recurrent Proteinuria Psoriasis Psoriatic arthropathy Pulmonary arterial hypertension Pulmonary fibrosis Pyoderma gangrenosum Rectal cancer Relapsing multiple sclerosis Relapsing-remitting multiple sclerosis Renal cancer Renal cancer metastatic Renal cell carcinoma Renal cell carcinoma stage IV Renal impairment Renal transplant Respiratory syncytial virus bronchiolitis Respiratory syncytial virus bronchitis Respiratory syncytial virus infection Retinal artery occlusion Reversible cerebral vasoconstriction syndrome Rhabdomyosarcoma Schizophrenia Secondary progressive multiple sclerosis Sedative therapy Severe myoclonic epilepsy of infancy Short stature Short-bowel syndrome Sickle cell anaemia Sickle cell disease Sinusitis Sjogren's syndrome Skin squamous cell carcinoma metastatic Skin squamous cell carcinoma recurrent Small cell lung cancer Small cell lung cancer recurrent Small for dates baby Soft tissue necrosis Squamous cell carcinoma of head and neck Status epilepticus Subdural haematoma Systemic lupus erythematosus Systemic scleroderma Testicular seminoma (pure) Testis cancer Tetanus immunisation Thrombosis prophylaxis Torticollis Transient ischaemic attack Tricuspid valve disease Triple negative breast cancer Turner's syndrome Type 1 diabetes mellitus Type 2 diabetes mellitus Type IIa hyperlipidaemia Vesicoureteric reflux VEXAS syndrome Viral infection Von Willebrand's disease Wheezing Yellow fever

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