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Brain stem glioma

  • Study of ONC206 for children and young adults with newly diagnosed or recurrent diffuse midline glioma and other recurrent brain tumors

    Recruiting

    1 1 1
    Investigated Diseases:
    • Ependymoma
    • Primitive neuroectodermal tumour
    • Brain stem glioma
    The Netherlands

  • Study on the Effectiveness of Sirolimus and Trametinib for Treating Diffuse Intrinsic Pontine Glioma in Children Aged 3-18 Years

    Recruiting

    2 1 1 1
    Investigated Diseases:
    • Brain stem glioma
    Investigated Drugs:
    • Sirolimus
    • Trametinib
    Poland

  • Study on ONC201 and Everolimus with Radiotherapy for Newly Diagnosed Diffuse Intrinsic Pontine Glioma and Other Diffuse Midline Gliomas in Children, Adolescents, and Adults

    Recruiting

    3 1 1 1
    Investigated Diseases:
    • Brain stem glioma
    Investigated Drugs:
    • 2,4,6,7,8,9-Hexahydro-4-((2-Methylphenyl)Methyl)-7-(Phenylmethyl)Imidazo(1,2-A)Pyrido(3,4-E)Pyrimidin-5(1H)-One
    • Everolimus
    Belgium Denmark Finland France Greece Norway +2

  • Using focused ultrasound to improve temozolomide treatment for patients with diffuse midline glioma

    Not yet recruiting

    1 1 1 1
    Investigated Drugs:
    • Temozolomide
    The Netherlands

  • Testing the Safety of Dendritic Cell and CAR-T Cell Combination Therapy in Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma

    Not yet recruiting

    1 1 1
    Investigated Diseases:
    • Brain stem glioma
    Investigated Drugs:
    • ARI0008
    Spain

  • Study on ONC201 and Paxalisib for Children and Young Adults with Diffuse Midline Gliomas, Including Diffuse Intrinsic Pontine Gliomas

    Not yet recruiting

    2 1 1
    Investigated Diseases:
    • Malignant glioma
    • Brain stem glioma
    Investigated Drugs:
    • Dordaviprone
    • Paxalisib
    The Netherlands
1 2
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European Clinical Trials Information Network

The European Clinical Trials Information Network is transforming access to clinical trial information for patients across Europe. By overcoming language barriers, our platform allows everyone, regardless of their native language, to easily find relevant and comprehensible clinical trial data. This innovative service connects patients to cutting-edge treatments, creating a unified European community where health and progress transcend borders.

This service is not affiliated with the European Commission, the EMA, or the official CTIS system. Most information comes from publicly available international clinical-trial registries, supplemented by data from academic centres, national regulators, and commercial sponsors. We aim to keep all content accurate and up to date.

Explore the full ecosystem of clinical research in Europe.

The information provided on this website is mainly derived from international public clinical trial databases (CTIS.eu). In addition, we are including supplementary sources, such as information provided by academic centers and national regulators, as well as information supplied by commercial sponsors (pharmaceutical companies and contract research organizations). We try to ensure that the information provided is accurate and up to date.

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