Treprostinil is an inhaled medication used to treat pulmonary hypertension, a condition where the blood pressure in the lungs is too high. In this study, it is delivered as an inhalation powder or solution to help improve how well a person can walk and to manage the symptoms of high blood pressure in the lungs associated with lung disease.

Pulmonary hypertension associated with interstitial lung disease – This condition occurs when there is high blood pressure in the arteries of the lungs caused by underlying lung tissue damage. The interstitial lung disease causes scarring or inflammation within the lung tissue, making it difficult for the lungs to expand and transfer oxygen. As the lung tissue becomes stiffer, the blood vessels in the lungs are compressed or damaged. This resistance forces the heart to work harder to pump blood through the lungs. Over time, the increased pressure in the lung arteries can lead to further changes in the blood vessels. The condition typically progresses as the lung damage and vascular resistance increase.