Riociguat is a medication used to treat chronic thromboembolic pulmonary hypertension (CTEPH), a condition where blood pressure in the lungs is high due to blood clots. The medication works by relaxing and widening blood vessels in the lungs, which helps to reduce blood pressure and make breathing easier for patients. It is taken orally and helps improve the ability to exercise and perform daily activities.

Balloon Pulmonary Angioplasty (BPA) is a medical procedure, not a medication, where a tiny balloon is inserted into narrowed blood vessels in the lungs. The balloon is inflated to widen these vessels, improving blood flow and reducing pressure in the lungs. This procedure is performed by specialists in a hospital setting and may require multiple sessions to treat all affected vessels.

Chronic thromboembolic pulmonary hypertension (CTEPH) – A rare form of high blood pressure that affects the lungs and is caused by old blood clots that block or narrow the pulmonary arteries. These blockages force the heart to work harder to pump blood through the lungs, leading to increased pressure in the pulmonary arteries. Over time, the blood vessels in the lungs become damaged and thickened, making it increasingly difficult for blood to flow properly. The condition typically develops after experiencing one or more blood clots in the lungs. Patients may experience gradually worsening shortness of breath, especially during physical activity, and may also feel tired or dizzy.