This study focuses on Nonsteroidal Anti-inflammatory Drug Exacerbated Respiratory Disease (N-ERD), a condition where patients experience breathing difficulties and increased sensitivity to certain pain medications. The study will evaluate the effectiveness of nasal lysine-aspirin, a modified form of aspirin, in managing symptoms of this condition.
The purpose of the study is to determine how well nasal lysine-aspirin helps control symptoms and improve quality of life for people with N-ERD. The study will use acetylsalicylic acid (aspirin) and sodium chloride solution as part of the treatment. Participants will receive the medication through the nose over a period of 49 days.
During the study, researchers will track changes in breathing problems, nasal congestion, sense of smell, and overall quality of life. They will also monitor how well asthma symptoms are controlled and any stomach-related side effects that may occur. The treatment involves gradually increasing the medication dose while carefully observing how participants respond to the treatment.



Belgium