This clinical trial is focused on studying the treatment of acne, a common skin condition that causes pimples and spots, particularly on the face. The study will compare the effectiveness of an oral medication called isotretinoin with other standard treatments currently used for moderate acne in individuals with skin of color. The goal is to determine if starting treatment with isotretinoin earlier can better reduce the severity of acne-related skin changes over a six-month period.

Participants in the study will receive either isotretinoin or one of the standard treatments, which may include medications like doxycycline, tretinoin cream, adapalene cream, or lymecycline. The study will last for up to six months, during which time participants will be asked to take selfies of their facial skin to monitor changes. These images will be analyzed using a special algorithm designed to assess the severity of acne and any related skin pigmentation issues.

The study will also look at other factors, such as the number and type of acne lesions, any side effects experienced, and the overall quality of life of participants. This information will help researchers understand the benefits and risks of using isotretinoin compared to other treatments for moderate acne in people with darker skin tones. The trial aims to provide valuable insights into the most effective ways to manage acne and improve skin health in this population.