This clinical trial focuses on treating patients with suspected sepsis, a serious condition where the body’s response to infection causes injury to its own tissues. The study compares two different antibiotic treatment approaches. The first approach combines narrow-spectrum antibiotics (penicillin, ampicillin, or cloxacillin) with gentamicin. The second approach uses broad-spectrum antibiotics (cefotaxime or piperacillin-tazobactam).
The purpose of this study is to determine if using a combination of narrow-spectrum antibiotics with gentamicin is as safe and effective as using broad-spectrum antibiotics alone in treating community-acquired sepsis. All medications in the study are given through an intravenous route, which means they are administered directly into the vein.
Participants in the study will receive one of these treatment approaches for up to three days. During and after treatment, doctors will monitor patients’ health status, including how well their kidneys are working and their overall recovery. The study will track various aspects of patient recovery, including time spent in the hospital and need for additional treatments.
Norway 