This study is being done in people with obesity or overweight who also have other health problems linked to body weight and who do not have diabetes. The treatment being studied is KAI-9531, given as a subcutaneous injection under the skin once a week. Some people in the study will receive a placebo.
The purpose of the study is to see how well KAI-9531 works and how safe it is. Participants are assigned by chance to receive either KAI-9531 or placebo, and neither the participants nor the study team know which treatment is being given during the study. The study continues for a long period while regular injections are given and health is followed over time.
During the study, body weight and other health measures are checked at planned visits. The study looks at changes in weight, waist size, blood pressure, blood fats such as triglycerides and cholesterol, blood sugar, and quality of life related to physical function. Safety is also monitored through medical checks, blood tests, heart tracing with ECG, and review of any side effects.
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