Hematologic malignancies and myeloid disorders
Research activity includes acute myeloid leukemia and myelodysplastic syndromes, with attention to lower-risk and high-risk disease settings, anemia management, and treatment-naive patient groups.
- Acute myeloid leukemia
- High-risk myelodysplastic neoplasia
- Lower-risk MDS
- MDS/MPN
Clinical interest also extends to erythroid response, transfusion independence, and regimens used in older or transplant-ineligible populations.
Head and neck cancer and biliary tract cancer
The sponsor supports studies in advanced laryngeal squamous cell carcinoma and hypopharyngeal squamous cell carcinoma, with a focus on organ-preserving treatment strategies and survival outcomes. Hilar cholangiocarcinoma is also represented among the solid tumor indications.
- Laryngeal squamous cell carcinoma
- Hypopharyngeal squamous cell carcinoma
- Laryngectomy-free survival
- Hilar cholangiocarcinoma
These trials reflect interest in locally advanced disease, surgical decision-making, and tumor-specific outcomes in complex oncologic care.
Autoimmune disease and vasculitis
Investigations cover systemic lupus erythematosus, systemic sclerosis, and granulomatous polyangiitis, with emphasis on immune-targeted treatment options for autoimmune B-cell driven disease.
- Systemic lupus erythematosus
- Systemic sclerosis
- Granulomatous polyangiitis
- Autoimmune B-cell driven disease
Clinical interests include control of inflammatory activity and safety considerations in chronic immune-mediated disorders.
Neurology and emergency care
Research includes established status epilepticus in older adults, with a specific focus on convulsive and nonconvulsive presentations in patients aged 65 years and older.
- Status epilepticus
- Convulsive and nonconvulsive seizures
- Older adult neurology
- Emergency seizure management
The therapeutic area reflects interest in acute seizure control and outcomes in a geriatric population.
Vascular medicine and post-surgical care
Additional work addresses peripheral arterial disease, strategies to reduce contrast-associated acute kidney injury during vascular interventions, and recovery after gastrectomy.
- Peripheral arterial disease
- Infrainguinal peripheral vascular interventions
- Contrast-associated acute kidney injury
- Post-gastrectomy care
Studies in this area also include pancreatic enzyme supplementation and quality-of-life outcomes after upper gastrointestinal surgery.
