Finnish Institute For Health And Welfare

COVID-19 immunology

Research activity in COVID-19 vaccination focuses on the characterization of immune responses after exposure to different vaccine formulations, with attention to both humoral immunity and cell-mediated immunity. The work is centered in Helsinki and reflects interest in post-vaccination immune protection.

  • COVID-19 infection
  • Vaccine-induced immunity
  • Humoral immune response
  • Cell-mediated immune response

Clinical interest includes the evaluation of immune markers relevant to protection against SARS-CoV-2 and the assessment of vaccine-related immune profiles in adult populations.

Avian influenza vaccine immunity

Trials in avian influenza examine immune responses generated by a customized H5N1 vaccine, with emphasis on strain-specific activity against the 2.3.4.4b clade. The research also addresses seasonal influenza and broader influenza virus immunity.

  • Avian influenza
  • H5N1 influenza
  • Seasonal influenza
  • Strain-specific antibody responses

Therapeutic interest is directed toward immune protection against emerging influenza A threats and the measurement of responses relevant to avian and seasonal vaccine targets.

Influenza antibody surveillance

Research on influenza immunity includes the assessment of antibody titres against circulating influenza virus strains and current-season vaccine strains. The studies use paired pre- and post-vaccination serum samples to define changes in serological protection.

  • Antibody titres
  • Circulating influenza strains
  • Seasonal vaccine strains
  • Serological response

This area supports monitoring of influenza vaccine responsiveness and immune coverage across contemporary viral strains in healthcare-related populations.

Healthcare personnel immunisation

Studies involving health care personnel focus on post-vaccination immune responses and protection against respiratory viral infections. The research environment supports examination of immune reactivity in a workforce exposed to influenza and COVID-19 risks.

  • Health care personnel
  • Occupational immunology
  • Respiratory virus exposure
  • Vaccination response

Clinical activity in this domain is aligned with the evaluation of immune responses in personnel groups relevant to public health preparedness and infectious disease control.

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Matched clinical trials

  • Study on Immune Responses to Avian Influenza Vaccine with A/Turkey/Turkey/1/05 (H5N1)-Like Strain in Patients with Avian and Seasonal Influenza

    Recruiting

    3 1 1 1
    Investigated diseases:
    Finland
  • Study on Immune Responses to COVID-19 Vaccines: Raxtozinameran, Bretovameran, and Drug Combination for COVID-19 Patients

    Not recruiting

    3 1 1 1
    Investigated diseases:
    Finland
  • Study on Immune Responses to Influenza Vaccines in Health Care Workers Using Polysorbate 80, Sodium Citrate, and Citric Acid Anhydrous

    Not recruiting

    3 1 1 1
    Investigated diseases:
    Finland