This clinical trial is focused on studying the immune responses induced by vaccines for avian influenza and seasonal influenza. The study involves two vaccines: VaxigripTetra, which is a quadrivalent influenza vaccine designed to protect against four different flu viruses, and the Zoonotic Influenza Vaccine Seqirus, which targets the H5N1 strain of avian influenza. The purpose of the study is to evaluate how the body’s immune system responds to these vaccines, particularly against the H5N1 2.3.4.4b clade of the avian influenza virus.
Participants in the study will receive the vaccines as injections. The VaxigripTetra vaccine is administered either into the muscle or under the skin, while the Zoonotic Influenza Vaccine Seqirus is given directly into the muscle. The study will monitor the immune response by measuring the levels of antibodies and specific immune cells in the blood. This will help determine how well the vaccines work in stimulating the body’s defense mechanisms against the influenza viruses.
The study will take place over a period of time, with participants receiving doses of the vaccines and then having their immune responses checked at various intervals. The main focus is on the body’s production of antibodies and the activation of immune cells that can fight off the influenza viruses. This research aims to provide valuable insights into the effectiveness of these vaccines in preventing influenza infections.



Finland