Critical Care and Sepsis
Research activity includes adult intensive care for patients requiring mechanical ventilation, with interest in oxygen management, respiratory support, and survival in critically ill populations. Additional work addresses septic shock and bacteremia, including treatment strategies for resistant bloodstream infections.
- Mechanical ventilation
- Septic shock
- Bloodstream infections
- Oxygen therapy
The sponsor also studies antimicrobial approaches in complicated urinary tract infections and infections caused by resistant Enterobacterales.
Maternal, Fetal, and Neonatal Care
Clinical research spans obstetric and neonatal conditions, including pre-labor rupture of membranes, premature rupture of membranes, and outcomes related to pregnancy and newborn respiratory support. Neonatal studies also focus on infants with perinatal asphyxiation and hypothermic treatment.
- Pre-labor rupture of membranes
- Perinatal asphyxiation
- Therapeutic hypothermia
- Newborn respiratory support
These topics place emphasis on perinatal outcomes and early-life neurocritical care.
Reproductive Medicine and Fertility
The sponsor investigates assisted reproductive technology, in vitro fertilization, and fertility outcomes in women with adenomyosis or other reproductive risk profiles. Research also includes strategies to improve ovarian reserve and follicular recruitment.
- Assisted reproductive technology
- In vitro fertilization
- Adenomyosis
- Ovarian reserve
Work in this area extends to infertility linked to tubal, male, and unexplained factors.
Oncology and Targeted Therapy
Research activity includes metastatic breast cancer, advanced pancreatic cancer, and extensive-stage small cell lung cancer. The sponsor also studies treatment approaches in tumors associated with BRCA and PALB2 alterations.
- Metastatic breast cancer
- Pancreatic cancer
- Small cell lung cancer
- BRCA and PALB2-related disease
These studies reflect interest in immunotherapy, radiotherapy, and molecularly defined malignancies.
Post-acute and Geroscience Research
Another area of focus is post-acute COVID syndrome, with attention to frailty, physical performance, and immune recovery. The sponsor also studies lifestyle-based interventions in relation to aging trajectories and functional status.
- Post-acute COVID syndrome
- Frailty
- Physical performance
- Immune function
This area links rehabilitation-oriented care with longer-term recovery after infection.
