Oncology and Neoplasms

At Centre Medico Chirurgical Ambroise Pare Hartmann, the oncology research portfolio focuses on colorectal cancer and metastatic breast cancer, with studies aimed at improving treatment effectiveness, refining surgery-related strategies, and identifying which patients are most likely to benefit from specific cancer therapies.

  • Locally advanced colon carcinoma, with research comparing pre-surgical treatment approaches to surgery alone
  • HR+, HER2- metastatic breast cancer, using blood-based tumor DNA signals to guide treatment selection
  • ctDNA-guided care in colorectal cancer, assessing how to better tailor therapy after surgery

This activity reflects a strong emphasis on personalized cancer care, especially through tumor DNA testing and treatment optimization for patients with digestive tract cancers.

Digestive System Diseases

The site also conducts clinical trials in digestive system diseases, mainly Crohn’s disease and ulcerative colitis, with an emphasis on evaluating new therapies that may improve symptom control, intestinal healing, and overall disease management.

  • Moderately to severely active ulcerative colitis, studying new options to improve safety and effectiveness
  • Crohn’s disease, with research focused on reducing inflammation and supporting better clinical response
  • Ulcerative colitis, including comparisons against placebo to assess symptom and endoscopic improvement

These studies show an active interest in advancing treatment choices for chronic inflammatory bowel conditions, supporting more effective care for patients at the Centre Medico Chirurgical Ambroise Pare Hartmann.