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Hepatic function abnormal

  • 4 clinical trials
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4 Clinical trials

Hepatic function abnormal

Not recruiting

Pharmacokinetic Study of Phenylbutyrate and Ursodoxicoltaurine (AMX0035) in Adults with Liver Impairment and Healthy Volunteers

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Phenylbutyrate
  • Sponsor:Amylyx Pharmaceuticals EMEA B.V.

Hepatic function abnormal

Not recruiting

Effect of moderate or severe liver impairment on the pharmacokinetics, safety and tolerability of camizestrant in post‑menopausal women

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Camizestrant
  • Sponsor:AstraZeneca AB

Hepatic function abnormal

Not recruiting

Phase 1 Study of REN001 Single‑Dose Pharmacokinetics in Adults with Normal, Mild, Moderate, or Severe Liver Impairment

InvestigationalNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Mavodelpar sodium
  • Sponsor:Reneo Pharmaceuticals Inc.

Hepatic function abnormal

Not recruiting

Pharmacokinetic Study of Oral TVB-2640 in Adults with Mild, Moderate, or Severe Hepatic Impairment and in Healthy Volunteers

InvestigationalNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:TVB-2640
  • Sponsor:Sagimet Biosciences Inc.
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