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Ovarian cancer recurrent Trials in Disease

Clinical trials for Ovarian cancer recurrent

Recruiting trials first

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18 clinical trials in this condition

Rinatabart Sesutecan with or without bevacizumab versus standard platinum‑based chemotherapy drug combination in patients with recurrent platinum‑sensitive ovarian cancer

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Genmab A/S

Rinatabart Sesutecan plus bevacizumab vs standard care as maintenance for recurrent platinum‑sensitive ovarian cancer after second‑line chemotherapy

Registered drugNo placebo
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Genmab A/S

Evaluation of Raludotatug Deruxtecan With Carboplatin, Paclitaxel, or Bevacizumab in Relapsed High-grade Serous Ovarian, Peritoneal, or Fallopian Tube Cancer

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Merck Sharp & Dohme LLC

Endometrial cancer+3

Recruiting

Study of ubamatamab alone or with cemiplimab for adults with ovarian, fallopian tube, peritoneal, or endometrial cancer that has come back

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Cemiplimab
  • Sponsor:Regeneron Pharmaceuticals Inc.
See all 18 trials →filters applied: condition = Ovarian cancer recurrent

In short

This article provides detailed information about 17 ongoing clinical trials studying new treatments for recurrent ovarian cancer. These trials are testing various medications and treatment combinations across multiple countries in Europe, offering potential treatment options for patients whose cancer has returned after initial therapy.

Summary

These 17 clinical trials represent a diverse range of investigational treatments for recurrent ovarian cancer. A significant number of trials are concentrated in countries such as France, Spain, Belgium, and Italy, reflecting strong research activity in these regions. Several trials focus on combination therapies, including immunotherapy agents like pembrolizumab and targeted therapies such as olaparib and avutometinib. Many studies specifically target platinum-resistant or platinum-sensitive disease, recognizing the different treatment needs for these patient populations. The trials also emphasize personalized medicine approaches, with some requiring specific genetic markers such as BRCA status, HLA-A2 phenotype, or folate receptor-alpha expression. Overall, these studies aim to improve treatment outcomes, extend progression-free survival, and enhance quality of life for patients with recurrent ovarian cancer.

This guide is here to help you understand the condition. It does not replace a conversation with your doctor, who knows your situation best.

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