In short
This article provides information about ongoing clinical trials related to oesophagogastroscopy, a procedure used to examine the inside of the upper digestive tract. Currently, there is 1 clinical trial investigating how medications can improve patient comfort and safety during this procedure.
Clinical trial locations
- Belgium
Study on the Effect of Lidocaine and Propofol on Sedation Levels During Gastroscopy in Adults
This trial is taking place in Belgium and focuses on improving the experience and safety of patients undergoing gastroscopy, a procedure where a small camera is used to look inside the stomach and upper digestive tract.
Main inclusion criteria: The trial is open to adults between 18 and 65 years old who need to have a gastroscopy under anesthesia at ERASME hospital. Participants must be in good or reasonably good health, with an ASA score of I or II. This scoring system helps classify how healthy someone is before a procedure, with score I meaning completely healthy and score II meaning having only mild health issues. Candidates should have a body mass index between 18 and 30 kg/m2, be able to speak and understand French, and must sign an informed consent form showing they understand and agree to participate in the study.
Main exclusion criteria: While the source data does not provide specific exclusion criteria, the strict inclusion requirements suggest that individuals outside the specified age range, those with more serious health conditions, those with BMI outside the normal range, or those unable to provide informed consent would not be eligible.
Focus and goal: The study aims to understand how the medication Lidocaine affects the amount of Propofol needed to keep patients comfortable during gastroscopy. Propofol is a medication that helps patients relax and fall asleep during medical procedures, while Lidocaine is used to numb areas and reduce pain. Researchers want to find the best way to use these medications together to improve patient comfort while maintaining safety. The trial is designed as a double-blind study, meaning neither the patients nor the researchers know who receives which treatment during the procedure. Throughout the study, vital signs like breathing and blood pressure are closely monitored, and both doctor and patient satisfaction are measured.
Investigational drugs: The trial uses two main medications. Lidocaine is given through an injection into a vein to see how it changes the effectiveness of Propofol. It works by blocking nerve signals that cause pain. Propofol is administered through a controlled infusion method to help patients relax or sleep during the procedure. The study measures how much Propofol is needed when Lidocaine is also used, with the goal of potentially reducing the amount required while maintaining patient comfort and safety.
Summary
Currently, there is one clinical trial investigating oesophagogastroscopy procedures, taking place in Belgium. This trial focuses on optimizing sedation during gastroscopy by studying the interaction between Lidocaine and Propofol. The research aims to improve both patient comfort and safety during this common diagnostic procedure. The study is particularly focused on finding ways to potentially reduce the amount of anesthesia needed while maintaining effective sedation, which could benefit patient recovery and reduce side effects. Patients interested in participating should meet specific health criteria and be able to communicate in French.
