In short
Currently, there is 1 ongoing clinical trial focused on improving the quality of life for patients who have undergone gastrectomy. This trial is investigating the use of pancreatic enzyme supplementation to help with digestion and overall well-being after stomach removal surgery.
Clinical trial locations
Study on the Effects of Amylase, Protease, and Rizolipase for Patients After Gastrectomy
This clinical trial is designed for patients who have undergone gastrectomy and are experiencing challenges with digestion and quality of life afterward. The study aims to evaluate whether taking a digestive enzyme supplement called Nortase® with every meal can improve daily well-being six months after surgery.
Who can participate:
- Adults aged 18 years or older
- Patients who have had gastrectomy (removal of part or all of the stomach)
- Both men and women are eligible
Who cannot participate:
The exclusion criteria indicate that patients who have had gastrectomy are the focus of this study, so specific exclusions beyond this primary condition are not detailed in the available information.
What the trial focuses on:
The main goal of this research is to determine if enzyme supplementation can lead to better disease-specific quality of life for patients recovering from gastrectomy. After stomach removal, the body may struggle to produce enough digestive enzymes, leading to symptoms such as bloating, gas, diarrhea, and difficulty absorbing nutrients. This trial investigates whether Nortase® can help alleviate these symptoms and improve physical well-being.
How the trial works:
Participants will be randomly assigned to receive either Nortase® or a placebo (an inactive substance). The study will last for six months, during which participants will take capsules with their meals. Throughout the trial, regular follow-up appointments will monitor health status and quality of life using questionnaires and physical assessments. At the end of the six-month period, a comprehensive evaluation will compare outcomes between those taking the enzyme supplement and those taking the placebo.
Investigational medication:
Nortase® contains pancreatic enzymes including amylase, protease, and rizolipase. These enzymes help break down carbohydrates, proteins, and fats in food, making it easier for the body to absorb nutrients. This type of supplementation is particularly important after gastrectomy, as the altered digestive system may not produce sufficient enzymes naturally. By supporting digestion, these enzymes may reduce common post-surgical symptoms and improve nutritional status.
Summary
There is currently one active clinical trial addressing the needs of patients after gastrectomy, taking place in Germany. This trial focuses specifically on the potential benefits of pancreatic enzyme supplementation in improving quality of life and managing digestive symptoms following stomach removal surgery. The research recognizes that post-gastrectomy syndrome can significantly impact daily life through digestive difficulties and nutritional challenges. By investigating enzyme supplementation, researchers aim to provide evidence-based solutions that may help patients better manage their recovery and long-term health after this major surgical procedure.
