Clinical trials in Utrecht – page 97

1 973 clinical trials in Utrecht, The Netherlands across 5 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Utrecht at a glance

1 973

clinical trials

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1 973 trials in Utrecht

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Acromegaly

Not recruiting

Study of ALXN2420 with somatostatin analogs for adults with acromegaly to evaluate effectiveness in lowering IGF-1 levels

Registered drug

Study of ALXN2420 with somatostatin analogs for adults with acromegaly to evaluate effectiveness in lowering IGF-1 levels

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:ALXN2420
Sponsor:Alexion Pharmaceuticals Inc.

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Type IIa hyperlipidaemia

Not recruiting

Study of laroprovstat (AZD0780) tablets to lower cholesterol levels in adults with inherited high cholesterol condition (heterozygous familial hypercholesterolemia)

Investigational

Study of laroprovstat (AZD0780) tablets to lower cholesterol levels in adults with inherited high cholesterol condition (heterozygous familial hypercholesterolemia)

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Laroprovstat
Sponsor:AstraZeneca AB

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Chronic kidney disease

Not recruiting

Study of vicadrostat and empagliflozin given together or separately in people with chronic kidney disease to test safety and effectiveness

Registered drug

Study of vicadrostat and empagliflozin given together or separately in people with chronic kidney disease to test safety and effectiveness

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:BI 690517
Sponsor:Boehringer Ingelheim Espana S.A.

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Hidradenitis

Not recruiting

Study of ruxolitinib cream applied to the skin for people with hidradenitis suppurativa

Investigational

Study of ruxolitinib cream applied to the skin for people with hidradenitis suppurativa

Investigational

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Ruxolitinib
Sponsor:Incyte Corp.

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Congenital cystic kidney disease

Not recruiting

Study of ABBV-CLS-628 to evaluate safety and effectiveness in adults with Autosomal Dominant Polycystic Kidney Disease

Investigational

Study of ABBV-CLS-628 to evaluate safety and effectiveness in adults with Autosomal Dominant Polycystic Kidney Disease

Investigational

The Netherlands

Participants:18–64 years
Substances:ABBV-CLS-628
Sponsor:Calico Life Sciences LLC

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Prostate cancer metastatic

Not recruiting

Study of ifinatamab deruxtecan alone or in combination with other treatments for patients with metastatic castration-resistant prostate cancer

Registered drugNo placebo

Study of ifinatamab deruxtecan alone or in combination with other treatments for patients with metastatic castration-resistant prostate cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abiraterone
Sponsor:Merck Sharp & Dohme LLC

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Breast cancer+2

Not recruiting

Study of 89Zr-trastuzumab PET/CT imaging and trastuzumab emtansine treatment in patients with advanced HER2-positive breast cancer

Registered drugNo placebo

Study of 89Zr-trastuzumab PET/CT imaging and trastuzumab emtansine treatment in patients with advanced HER2-positive breast cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Trastuzumab
Sponsor:Institut Jules Bordet

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Respiratory syncytial virus infection+1

Not recruiting

Studying the Effect of Nirsevimab Immunization on Antibody Development After RSV Infection in Healthy Infants

Registered drugNo placebo

Studying the Effect of Nirsevimab Immunization on Antibody Development After RSV Infection in Healthy Infants

Registered drugNo placebo

The Netherlands

Participants:0–17 years · Healthy volunteers
Substances:Nirsevimab
Sponsor:Rijksinstituut voor Volksgezondheid en Milieu (RIVM)

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Acute coronary syndrome+1

Not recruiting

Reduced Dose Prasugrel Monotherapy After Stent Placement in Patients with Acute and Chronic Coronary Syndrome

Registered drugNo placebo

Reduced Dose Prasugrel Monotherapy After Stent Placement in Patients with Acute and Chronic Coronary Syndrome

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Prasugrel
Sponsor:Amsterdam UMC Stichting

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Sickle cell disease

Not recruiting

Study on the Effects of Tebapivat and AG-946 in Patients with Sickle Cell Disease

Investigational

Study on the Effects of Tebapivat and AG-946 in Patients with Sickle Cell Disease

Investigational

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Sponsor:Agios Pharmaceuticals Inc.

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Colorectal cancer+1

Not recruiting

Study on the Safety and Effects of GSK4418959 and Dostarlimab for Adults with Colorectal Cancer with Mismatch Repair Deficiency or High Microsatellite Instability

Registered drugNo placebo

Study on the Safety and Effects of GSK4418959 and Dostarlimab for Adults with Colorectal Cancer with Mismatch Repair Deficiency or High Microsatellite Instability

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dostarlimab
Sponsor:Glaxosmithkline Research & Development Limited

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Colitis ulcerative

Not recruiting

Comparison of Risankizumab and Vedolizumab for Treatment of Moderate to Severe Ulcerative Colitis in Adults Who Have Not Received Targeted Therapies

Registered drugNo placebo

Comparison of Risankizumab and Vedolizumab for Treatment of Moderate to Severe Ulcerative Colitis in Adults Who Have Not Received Targeted Therapies

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Risankizumab
Sponsor:AbbVie Deutschland GmbH & Co. KG

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Clinical research in Utrecht

What the registry says about research in the country

01 Cardiovascular Research

Innovative studies focusing on TTR amyloidosis and heart disease treatments, investigating new therapeutic approaches for cardiac conditions. Clinical trials evaluate novel medications for improving patient mobility and cardiac function.

Heart Disease Management
Cardiac Biomarkers
Treatment Efficacy

Research aims to enhance quality of life for patients with hereditary and wild-type ATTR cardiomyopathy.

02 Cancer Research

Comprehensive studies in gastric cancer, bladder cancer, and neuroblastoma, exploring innovative treatment combinations and diagnostic methods.

Immunotherapy Applications
Targeted Therapies
Diagnostic Imaging

Advanced trials combining established treatments with novel approaches to improve patient outcomes.

03 Neurological Disorders

Groundbreaking research in Amyotrophic Lateral Sclerosis and chronic inflammatory conditions, focusing on innovative treatments and disease modification strategies.

Gene-Targeted Therapies
Neurological Function
Disease Progression

Studies aim to develop effective treatments for rare and challenging neurological conditions.

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