Clinical trials in Utrecht – page 25

625 clinical trials in Utrecht, The Netherlands across 5 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Utrecht at a glance

625

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625 trials in Utrecht

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Pancreatic carcinoma

Not yet recruiting

Phase II/III trial of autologous dendritic cells loaded with allogenic mesothelioma lysate in patients with borderline resectable pancreatic cancer

InvestigationalNo placebo

Phase II/III trial of autologous dendritic cells loaded with allogenic mesothelioma lysate in patients with borderline resectable pancreatic cancer

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Autologous dendritic cells loaded with allogenic allogeneic lysate of mesothelioma cell lines
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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B precursor type acute leukaemia

Not yet recruiting

Study of asciminib, dexamethasone, blinatumomab, and vincristine sulfate in children and young adults with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia

Registered drugNo placebo

Study of asciminib, dexamethasone, blinatumomab, and vincristine sulfate in children and young adults with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Blinatumomab
Sponsor:Novartis Pharma AG

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Graft versus host disease

Not yet recruiting

Safety and Efficacy of MaaT013 with Vancomycin in Children and Adolescents with Gastrointestinal Acute Graft‑versus‑Host Disease

Registered drugNo placebo

Safety and Efficacy of MaaT013 with Vancomycin in Children and Adolescents with Gastrointestinal Acute Graft‑versus‑Host Disease

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Vancomycin
Sponsor:Maat Pharma

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A study to evaluate the safety and effectiveness of subcutaneous blinatumomab in adults and adolescents with relapsed, refractory, or minimal residual disease positive B-cell precursor acute lymphoblastic leukemia.

Registered drugNo placebo

A study to evaluate the safety and effectiveness of subcutaneous blinatumomab in adults and adolescents with relapsed, refractory, or minimal residual disease positive B-cell precursor acute lymphoblastic leukemia.

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Blinatumomab
Sponsor:Amgen Inc.

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Craniopharyngioma

Not yet recruiting

A study of tovorafenib for children and young adults with newly diagnosed or recurrent craniopharyngioma

InvestigationalNo placebo

A study of tovorafenib for children and young adults with newly diagnosed or recurrent craniopharyngioma

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Tovorafenib
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Brain stem glioma

Not yet recruiting

Using focused ultrasound to improve temozolomide treatment for patients with diffuse midline glioma

Registered drugNo placebo

Using focused ultrasound to improve temozolomide treatment for patients with diffuse midline glioma

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Temozolomide
Sponsor:Universitair Medisch Centrum Utrecht

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Post-traumatic stress disorder

Not yet recruiting

A study to evaluate if hydrocortisone helps reduce symptoms of post-traumatic stress disorder in patients after exposure to a traumatic event.

Registered drug

A study to evaluate if hydrocortisone helps reduce symptoms of post-traumatic stress disorder in patients after exposure to a traumatic event.

Registered drug

The Netherlands

Participants:18–64 years · Healthy volunteers
Substances:Hydrocortisone
Sponsor:Amsterdam UMC Stichting

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Glioblastoma

Not yet recruiting

Phase 3 Randomized Study of Niraparib Tosilate Monohydrate vs. Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

Registered drugNo placebo

Phase 3 Randomized Study of Niraparib Tosilate Monohydrate vs. Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Temozolomide
Sponsor:Neurotrials LLC

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Testing inotuzumab ozogamicin and blinatumomab with drug combination for children with relapsed precursor B-cell acute lymphoblastic leukemia

Not yet recruiting

Registered drugNo placebo

Testing inotuzumab ozogamicin and blinatumomab with drug combination for children with relapsed precursor B-cell acute lymphoblastic leukemia

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Blinatumomab
Sponsor:Charite Universitaetsmedizin Berlin KöR

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Acute lymphocytic leukaemia+6

Not yet recruiting

A Study Testing the Safety of CD19-Targeted CAR T-Cell Therapy in Children and Young Adults with Relapsed or Refractory B-Cell Cancers

InvestigationalNo placebo

A Study Testing the Safety of CD19-Targeted CAR T-Cell Therapy in Children and Young Adults with Relapsed or Refractory B-Cell Cancers

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:MB-HUCART19.1
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Acute lymphocytic leukaemia+2

Not yet recruiting

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo

The Netherlands

Participants:0–17 years
Substances:Blinatumomab
Sponsor:Amgen Inc.

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Angina pectoris

Not yet recruiting

A Study of Encoberminogene Rezmadenovec Gene Therapy for Patients with Refractory Angina Due to Coronary Artery Disease

InvestigationalNo placebo

A Study of Encoberminogene Rezmadenovec Gene Therapy for Patients with Refractory Angina Due to Coronary Artery Disease

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Flurpiradaz F 18
Sponsor:Xylocor Therapeutics Inc.

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Clinical research in Utrecht

What the registry says about research in the country

01 Cardiovascular Research

Innovative studies focusing on TTR amyloidosis and heart disease treatments, investigating new therapeutic approaches for cardiac conditions. Clinical trials evaluate novel medications for improving patient mobility and cardiac function.

Heart Disease Management
Cardiac Biomarkers
Treatment Efficacy

Research aims to enhance quality of life for patients with hereditary and wild-type ATTR cardiomyopathy.

02 Cancer Research

Comprehensive studies in gastric cancer, bladder cancer, and neuroblastoma, exploring innovative treatment combinations and diagnostic methods.

Immunotherapy Applications
Targeted Therapies
Diagnostic Imaging

Advanced trials combining established treatments with novel approaches to improve patient outcomes.

03 Neurological Disorders

Groundbreaking research in Amyotrophic Lateral Sclerosis and chronic inflammatory conditions, focusing on innovative treatments and disease modification strategies.

Gene-Targeted Therapies
Neurological Function
Disease Progression

Studies aim to develop effective treatments for rare and challenging neurological conditions.

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