Clinical trials in Leiden – page 75

1 938 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leiden at a glance

1 938

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1 938 trials in Leiden

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Type 1 diabetes mellitus+1

Not yet recruiting

A study testing dapagliflozin and SC0062 together compared to SC0062 alone in adults with type 1 diabetes and chronic kidney disease

Registered drugNo placebo

A study testing dapagliflozin and SC0062 together compared to SC0062 alone in adults with type 1 diabetes and chronic kidney disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Dapagliflozin
Sponsor:Universitair Medisch Centrum Groningen

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Gastrointestinal carcinoma+4

Not yet recruiting

A Study Using Indocyanine Green Fluorescence Imaging to Help Surgeons Better Identify Tumor Edges During Cancer Surgery in Patients with Solid Tumors

Registered drugNo placebo

A Study Using Indocyanine Green Fluorescence Imaging to Help Surgeons Better Identify Tumor Edges During Cancer Surgery in Patients with Solid Tumors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Indocyanine Green
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Cardiac sarcoidosis

Not yet recruiting

A Study Testing the Accuracy of 68Ga-Pentixafor PET/CT Imaging in Patients with Cardiac Sarcoidosis

InvestigationalNo placebo

A Study Testing the Accuracy of 68Ga-Pentixafor PET/CT Imaging in Patients with Cardiac Sarcoidosis

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Pentixafor
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Hormone-dependent prostate cancer+1

Not yet recruiting

Study of Darolutamide to Increase PSMA Protein Expression in Patients with Hormone Sensitive Prostate Cancer

Registered drugNo placebo

Study of Darolutamide to Increase PSMA Protein Expression in Patients with Hormone Sensitive Prostate Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Darolutamide
Sponsor:Amsterdam UMC Stichting

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Lung neoplasm malignant

Not yet recruiting

Testing F-18-AraG imaging scan reliability in patients with lung cancer using repeat scans

Registered drugNo placebo

Testing F-18-AraG imaging scan reliability in patients with lung cancer using repeat scans

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Nelarabine
Sponsor:Amsterdam UMC Stichting

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Breast cancer

Not yet recruiting

Study of 6qc-ICG applied to the skin during breast cancer surgery to help surgeons see tumor edges in patients having breast conserving operations

Investigational

Study of 6qc-ICG applied to the skin during breast cancer surgery to help surgeons see tumor edges in patients having breast conserving operations

Investigational

The Netherlands

Participants:18–64 years · 65+ years · Healthy volunteers
Substances:6QC-ICG
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Acute lymphocytic leukaemia+2

Not yet recruiting

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo

The Netherlands

Participants:0–17 years
Substances:Blinatumomab
Sponsor:Amgen Inc.

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Cervix carcinoma

Not yet recruiting

A study of pembrolizumab and lenvatinib for patients with high risk locally advanced cervical cancer after chemoradiotherapy and brachytherapy

Registered drugNo placebo

A study of pembrolizumab and lenvatinib for patients with high risk locally advanced cervical cancer after chemoradiotherapy and brachytherapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Lenvatinib
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Angina pectoris

Not yet recruiting

A Study of Encoberminogene Rezmadenovec Gene Therapy for Patients with Refractory Angina Due to Coronary Artery Disease

InvestigationalNo placebo

A Study of Encoberminogene Rezmadenovec Gene Therapy for Patients with Refractory Angina Due to Coronary Artery Disease

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Flurpiradaz F 18
Sponsor:Xylocor Therapeutics Inc.

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Haemodialysis

Not yet recruiting

Study of Intradialytic Parenteral Nutrition for Muscle Protein Production in Patients on Long-term Hemodialysis Treatment

Registered drugNo placebo

Study of Intradialytic Parenteral Nutrition for Muscle Protein Production in Patients on Long-term Hemodialysis Treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Alanine
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Endocrine ophthalmopathy

Not yet recruiting

Study Using Gallium-68 FAPI PET/MRI Imaging to Measure Disease Activity in Patients with Graves' Eye Disease

InvestigationalNo placebo

Study Using Gallium-68 FAPI PET/MRI Imaging to Measure Disease Activity in Patients with Graves' Eye Disease

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Acquired ATTR amyloidosis

Not yet recruiting

A Study of Acoramidis for Long-Term Safety in Patients with Newly Diagnosed Variant Transthyretin Amyloid Cardiomyopathy

InvestigationalNo placebo

A Study of Acoramidis for Long-Term Safety in Patients with Newly Diagnosed Variant Transthyretin Amyloid Cardiomyopathy

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Eidos Therapeutics Inc.

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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