Clinical trials in Leiden – page 66

1 938 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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1 938

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1 938 trials in Leiden

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Hormone-refractory prostate cancer

Recruiting

Study on Docetaxel, Cabazitaxel, and Darolutamide for Men with Metastatic Castration-Resistant Prostate Cancer

Registered drugNo placebo

Study on Docetaxel, Cabazitaxel, and Darolutamide for Men with Metastatic Castration-Resistant Prostate Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cabazitaxel
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Pancreatic carcinoma+1

Recruiting

Study on Timing of Chemotherapy with Paclitaxel Albumin-Bound and Drug Combination for Patients with Metastatic Pancreatic Cancer

Registered drugNo placebo

Study on Timing of Chemotherapy with Paclitaxel Albumin-Bound and Drug Combination for Patients with Metastatic Pancreatic Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Fluorouracil
Sponsor:Amsterdam UMC Stichting

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Neoplasm malignant

Recruiting

Study on Preventing Opioid-Induced Constipation in Advanced Cancer Patients Using Magnesium Hydroxide and Macrogol 3350 Combination

Registered drugNo placebo

Study on Preventing Opioid-Induced Constipation in Advanced Cancer Patients Using Magnesium Hydroxide and Macrogol 3350 Combination

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Macrogol 3350
Sponsor:Amsterdam UMC Stichting

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Colorectal cancer

Recruiting

Study on Rectal Cancer Treatment with Radiotherapy, Atezolizumab, and Bevacizumab for Patients with Low- to Intermediate-Risk

Registered drugNo placebo

Study on Rectal Cancer Treatment with Radiotherapy, Atezolizumab, and Bevacizumab for Patients with Low- to Intermediate-Risk

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Atezolizumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Acute lymphocytic leukaemia+4

Recruiting

Study of Dasatinib and Venetoclax for Children with Relapsed or Refractory Leukemia or Lymphoma with MAPK/SRC Pathway Mutation

Registered drugNo placebo

Study of Dasatinib and Venetoclax for Children with Relapsed or Refractory Leukemia or Lymphoma with MAPK/SRC Pathway Mutation

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Dasatinib
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Transitional cell carcinoma

Recruiting

Study on Chemo-Immunotherapy with Avelumab for Patients with Locally Advanced Urothelial Cancer

Registered drugNo placebo

Study on Chemo-Immunotherapy with Avelumab for Patients with Locally Advanced Urothelial Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Avelumab
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Systemic scleroderma

Recruiting

Study on Mesenchymal Stem Cells for Patients with Systemic Sclerosis and Digital Ulcers

Investigational

Study on Mesenchymal Stem Cells for Patients with Systemic Sclerosis and Digital Ulcers

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Human Mesenchymal Stem Cells
Sponsor:Universitair Medisch Centrum Utrecht

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Non-small cell lung cancer

Recruiting

Study on Durvalumab and Radiotherapy for Patients with Early-Stage Non-Small Cell Lung Cancer

Registered drugNo placebo

Study on Durvalumab and Radiotherapy for Patients with Early-Stage Non-Small Cell Lung Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Durvalumab
Sponsor:Amsterdam UMC Stichting

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Crohn's disease

Recruiting

Study of Lutikizumab, ABBV-382, and Risankizumab for Adults with Moderate to Severe Crohn's Disease

InvestigationalNo placebo

Study of Lutikizumab, ABBV-382, and Risankizumab for Adults with Moderate to Severe Crohn's Disease

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:ABBV-8736
Sponsor:AbbVie Deutschland GmbH & Co. KG

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Lichen planopilaris

Not yet recruiting

Safety and Efficacy of Oral Brepocitinib in Adults with Lichen Planopilaris: A Randomized, Double‑Blind, Placebo‑Controlled Phase 2/3 Study

Investigational

Safety and Efficacy of Oral Brepocitinib in Adults with Lichen Planopilaris: A Randomized, Double‑Blind, Placebo‑Controlled Phase 2/3 Study

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Priovant Therapeutics Inc.

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Ovarian cancer

Not yet recruiting

Study of gsk5733584 with bevacizumab versus standard drug combination in patients with platinum-sensitive ovarian cancer

Registered drugNo placebo

Study of gsk5733584 with bevacizumab versus standard drug combination in patients with platinum-sensitive ovarian cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Glaxosmithkline Research & Development Limited

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Systemic scleroderma+2

Not yet recruiting

Long‑term Safety and Tolerability of Anifrolumab in Adults with Systemic Lupus Erythematosus Who Completed Prior Study

Registered drugNo placebo

Long‑term Safety and Tolerability of Anifrolumab in Adults with Systemic Lupus Erythematosus Who Completed Prior Study

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Anifrolumab
Sponsor:AstraZeneca AB

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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