Clinical trials in Leiden – page 65

1 938 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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1 938 trials in Leiden

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Leiomyosarcoma+1

Recruiting

Study on the Effect of Chemotherapy with Ifosfamide, Dacarbazine, and Epirubicin Hydrochloride Before Surgery for Patients with High-Risk Retroperitoneal Sarcoma

Registered drugNo placebo

Study on the Effect of Chemotherapy with Ifosfamide, Dacarbazine, and Epirubicin Hydrochloride Before Surgery for Patients with High-Risk Retroperitoneal Sarcoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dacarbazine
Sponsor:European Organisation For Research And Treatment Of Cancer

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Rectal cancer

Recruiting

Study of drug combination (capecitabine, fluorouracil, oxaliplatin, calcium folinate) to prevent cancer recurrence in patients with detectable ctDNA after rectal cancer surgery

Registered drugNo placebo

Study of drug combination (capecitabine, fluorouracil, oxaliplatin, calcium folinate) to prevent cancer recurrence in patients with detectable ctDNA after rectal cancer surgery

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Calcium Folinate
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Gastrointestinal carcinoma

Recruiting

Study on Capecitabine and Oxaliplatin for Patients with Advanced or Metastatic Gastrointestinal Cancer with CES1 Variant

Registered drugNo placebo

Study on Capecitabine and Oxaliplatin for Patients with Advanced or Metastatic Gastrointestinal Cancer with CES1 Variant

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Acute lymphocytic leukaemia

Recruiting

Study on Tioguanine and Drug Combination for Patients Aged 0-45 with Newly Diagnosed Acute Lymphoblastic Leukemia

Registered drugNo placebo

Study on Tioguanine and Drug Combination for Patients Aged 0-45 with Newly Diagnosed Acute Lymphoblastic Leukemia

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Blinatumomab
Sponsor:Karolinska University Hospital

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Coronary artery disease+1

Recruiting

Study on Clopidogrel and Acetylsalicylic Acid for Patients with Coronary Artery Disease and Non-ST-segment Elevation Acute Coronary Syndrome

Registered drugNo placebo

Study on Clopidogrel and Acetylsalicylic Acid for Patients with Coronary Artery Disease and Non-ST-segment Elevation Acute Coronary Syndrome

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Acetylsalicylic Acid
Sponsor:Sint Antonius Ziekenhuis Stichting

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Glycogen storage disease type II

Recruiting

Study on the Safety and Efficacy of Avalglucosidase Alfa for Patients Aged 5 and Older with Non-Classic Pompe Disease

Registered drugNo placebo

Study on the Safety and Efficacy of Avalglucosidase Alfa for Patients Aged 5 and Older with Non-Classic Pompe Disease

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Avalglucosidase Alfa
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Neoplasm

Recruiting

Study on Everolimus and Drug Combination for Children with Relapsed or Refractory Pediatric Cancer

Registered drugNo placebo

Study on Everolimus and Drug Combination for Children with Relapsed or Refractory Pediatric Cancer

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Avelumab
Sponsor:Institut Gustave Roussy

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Non-small cell lung cancer

Recruiting

Study on the Safety of Tremelimumab Injections for Early-Stage Non-Small Cell Lung Cancer Patients

Registered drug

Study on the Safety of Tremelimumab Injections for Early-Stage Non-Small Cell Lung Cancer Patients

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Sodium Chloride
Sponsor:Amsterdam UMC Stichting

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Myelofibrosis+1

Recruiting

Study on Tasquinimod for Patients with Myelofibrosis Who Are Refractory or Intolerant to JAK2 Inhibitors

InvestigationalNo placebo

Study on Tasquinimod for Patients with Myelofibrosis Who Are Refractory or Intolerant to JAK2 Inhibitors

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Tasquinimod
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Colorectal cancer metastatic+1

Recruiting

Study of petosemtamab alone or with drug combination for patients with advanced colorectal cancer and other solid tumors

Registered drugNo placebo

Study of petosemtamab alone or with drug combination for patients with advanced colorectal cancer and other solid tumors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Calcium Folinate
Sponsor:Genmab A/S

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Neoplasm

Recruiting

Study of SAR445877 and Cetuximab for Adults with Advanced Solid Tumors

Registered drugNo placebo

Study of SAR445877 and Cetuximab for Adults with Advanced Solid Tumors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Sanofi-Aventis Recherche & Developpement

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Malabsorption

Recruiting

Study on the Effects of ELGN-2112 (Human Insulin) for Treating Intestinal Malabsorption in Preterm Infants

Investigational

Study on the Effects of ELGN-2112 (Human Insulin) for Treating Intestinal Malabsorption in Preterm Infants

Investigational

The Netherlands

Participants:0–17 years
Substances:Insulin Human
Sponsor:Elgan Pharma Ltd.

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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