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Clinical trials in Cracow – page 21

1 228 clinical trials in Cracow, Poland across 15 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Cracow at a glance
1 228
clinical trials
  • Research sites15
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1 228 trials in Cracow

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Crohn's disease

Recruiting

Study of icotrokinra for adults with moderately to severely active Crohn's disease

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

Testing icotrokinra compared to placebo for adults and adolescents with moderately to severely active ulcerative colitis

Investigational
Countries:PolandPoland
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

HIV infection

Recruiting

A study testing VH4524184 with emtricitabine and tenofovir alafenamide compared to dolutegravir and lamivudine in adults with HIV-1 who have not received treatment before

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Dolutegravir Sodium
  • Sponsor:Viiv Healthcare UK Limited

Testing Stem Cell Transplant Methods and Medications Including Ruxolitinib and Blinatumomab for Children and Young Adults with Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:PolandPoland
  • Participants:0–17 years · 18–64 years
  • Substances:Blinatumomab
  • Sponsor:Ospedale Pediatrico Bambino Gesu

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:Pfizer Inc.

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Depemokimab
  • Sponsor:Glaxosmithkline Research & Development Limited

A Study Testing Casdatifan and Cabozantinib Compared to Placebo and Cabozantinib in Patients With Advanced Clear Cell Kidney Cancer

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:AB521
  • Sponsor:Arcus Biosciences Inc.

Breast cancer+2

Recruiting

A Study Comparing RLY-2608 and Fulvestrant with Capivasertib and Fulvestrant for Patients with PIK3CA-Mutant Hormone Receptor Positive, HER2-Negative Advanced Breast Cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Capivasertib
  • Sponsor:Relay Therapeutics Inc.

A study to evaluate the long-term safety and effectiveness of afimkibart in patients with atopic dermatitis who took part in previous afimkibart studies

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:RO7790121
  • Sponsor:F. Hoffmann-La Roche AG

Prostate cancer

Recruiting

A study of saruparib with radiotherapy and hormone therapy for men with high-risk prostate cancer who have a BRCA gene mutation

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone Acetate
  • Sponsor:AstraZeneca AB

A Study of Belzutifan and Zanzalintinib Compared to Cabozantinib in Patients with Advanced Kidney Cancer that Returned After Previous Treatment

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Belzutifan
  • Sponsor:Merck Sharp & Dohme LLC

A study comparing injection under the skin versus infusion into the vein of tislelizumab with chemotherapy for patients with advanced gastric or gastroesophageal junction cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Tislelizumab
  • Sponsor:BeOne Medicines AG

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Clinical research in Cracow

What the registry says about research in the country

01 Metabolic, Endocrine, and Kidney Research

In Kraków, clinical trials in type 2 diabetes, chronic kidney disease, hyperlipidemia, and hypoparathyroidism are exploring new ways to improve long-term disease control and protect organ function.

  • Testing treatments for better blood sugar control
  • Evaluating options to slow kidney decline
  • Studying hormonal disorders and calcium balance
  • Assessing therapies for metabolic complications

These studies aim to refine treatment effectiveness and support patients living with chronic metabolic conditions.

02 Cardiovascular and Heart Failure Trials

A strong group of studies focuses on cardiovascular disease, heart failure, hypertension, atrial fibrillation, and acute myocardial infarction, with the goal of improving prevention and treatment outcomes.

  • Reducing the risk of major heart events
  • Improving care for chronic and worsening heart failure
  • Studying blood pressure control in difficult-to-treat patients
  • Evaluating strategies for stroke and infarction prevention

Several trials in the city are also looking at ways to improve recovery after cardiac procedures and lower future cardiovascular risk.

03 Immunology, Inflammation, and Autoimmune Disease

Many trials in Kraków address immune-mediated diseases such as systemic lupus erythematosus, Sjögren’s syndrome, and psoriatic arthritis, with an emphasis on better symptom control and disease suppression.

  • Studying therapies for autoimmune inflammation
  • Evaluating treatment effectiveness in lupus and related disorders
  • Assessing new approaches for arthritis linked to immune disease
  • Exploring long-term safety and tolerability

Research in this area also includes conditions where immune dysfunction affects multiple organs and daily quality of life.

04 Dermatology and Skin Disorders

Skin-focused trials cover atopic dermatitis, plaque psoriasis, vitiligo, alopecia areata, and hidradenitis suppurativa, reflecting a broad effort to improve visible and often persistent inflammatory conditions.

  • Testing new therapies for chronic skin inflammation
  • Evaluating hair regrowth and skin repigmentation
  • Studying symptom relief in psoriasis and eczema
  • Assessing patient comfort and treatment durability

These studies aim to offer more effective options for people living with conditions that can strongly affect daily well-being.

05 Respiratory and Allergy Research

Trials in asthma, COPD, chronic rhinosinusitis with nasal polyps, and allergic rhinitis are examining ways to improve breathing, reduce flare-ups, and ease chronic airway inflammation.

  • Evaluating treatments for severe and difficult-to-control asthma
  • Studying new options for chronic obstructive lung disease
  • Improving symptom relief in nasal and sinus inflammation
  • Looking at long-term control of allergic airway disease

Researchers are especially interested in therapies that may lower exacerbation rates and improve everyday respiratory function.

06 Gastroenterology and Liver Disease

Clinical research in ulcerative colitis, Crohn’s disease, non-alcoholic steatohepatitis, and alcohol-related liver disease is aiming to improve inflammation control and reduce long-term complications.

  • Testing treatments for inflammatory bowel disease
  • Evaluating approaches to maintain remission
  • Exploring therapies for liver inflammation and damage
  • Studying digestive symptoms and quality of life

Some studies also address patients with more complex digestive conditions that need long-term management.

07 Neurology and Cognitive Health

Neurological studies include multiple sclerosis, Alzheimer’s disease, migraine, epilepsy, and narcolepsy, reflecting broad interest in both chronic and progressive brain disorders.

  • Assessing treatments for relapsing and progressive nerve disease
  • Studying memory and cognitive decline
  • Testing therapies for seizure control
  • Exploring options for sleepiness and migraine burden

These trials focus on symptom reduction, disease slowing, and better day-to-day functioning for patients with neurological conditions.

08 Oncology and Hematology

Research on breast cancer, non-small cell lung cancer, lymphoma, multiple myeloma, and leukemia is an important part of the trial landscape in Kraków.

  • Testing new cancer treatment combinations
  • Evaluating strategies for relapsed or hard-to-treat disease
  • Studying immune and targeted therapies
  • Assessing response and disease control in blood cancers

These studies seek to improve survival, response rates, and treatment options for both solid tumors and blood-related cancers.

09 Rare Disease, Genetics, and Pediatric Disorders

Several trials address genetic and rare diseases such as Marfan syndrome, congenital adrenal hyperplasia, nephrotic syndrome, and other inherited conditions.

  • Exploring therapies for rare genetic disorders
  • Studying hormone and growth-related abnormalities
  • Evaluating treatment options for childhood-onset disease
  • Improving disease monitoring and symptom management

These studies are especially valuable for patients with uncommon conditions where treatment choices are limited.

10 Infectious Disease and Virology

Trials in COVID-19, HIV-1 infection, meningococcal infection, and fungal infections are focused on prevention, treatment, and better disease control.

  • Testing approaches for viral and bacterial infection management
  • Evaluating prevention strategies in high-risk groups
  • Studying treatment for acute fungal disease
  • Looking at immune protection and infection reduction

This area includes both active treatment studies and work aimed at lowering future infection risk.

11 Musculoskeletal and Rheumatologic Conditions

Studies in juvenile idiopathic arthritis, axial spondyloarthritis, systemic sclerosis, and chronic pain-related disorders are examining ways to reduce inflammation and improve mobility.

  • Evaluating treatments for inflammatory joint disease
  • Studying pain relief and functional improvement
  • Exploring disease control in connective tissue disorders
  • Assessing longer-term symptom management

Researchers are looking for therapies that can ease stiffness, pain, and movement limitations over time.

12 Women’s Health and Reproductive Medicine

Trials involving endometriosis, pregnancy-related conditions, contraception, and menopausal symptoms reflect a broad commitment to women’s health research.

  • Testing therapies for endometriosis-related pain
  • Studying options in reproductive and hormonal health
  • Evaluating prevention of pregnancy
  • Exploring symptom relief for vasomotor complaints

These studies are designed to improve comfort, planning options, and quality of life across different stages of life.

13 Psychiatry, Sleep, and Behavior Research

Some trials focus on behavior change, smoking and vaping cessation, and sleep-related problems such as narcolepsy and excessive daytime sleepiness.

  • Supporting quitting nicotine use and vaping
  • Studying treatments for sleep-wake disorders
  • Assessing changes in alertness and daily functioning
  • Exploring behavioral support alongside medical treatment

These studies combine medical and behavioral approaches to help people improve daily habits and alertness.

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