Clinical trials in Bilthoven – page 66

1 718 clinical trials in Bilthoven, The Netherlands across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Bilthoven at a glance

1 718

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1 718 trials in Bilthoven

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Glioblastoma

Not yet recruiting

Phase 3 Randomized Study of Niraparib Tosilate Monohydrate vs. Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

Registered drugNo placebo

Phase 3 Randomized Study of Niraparib Tosilate Monohydrate vs. Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Temozolomide
Sponsor:Neurotrials LLC

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Abnormal behaviour

Not yet recruiting

Study of pipamperone and aripiprazole for challenging behaviors in people with intellectual disabilities

Registered drugNo placebo

Study of pipamperone and aripiprazole for challenging behaviors in people with intellectual disabilities

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Aripiprazole
Sponsor:Stichting GGZ Drenthe

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Plasma cell myeloma refractory

Not yet recruiting

A Study of Linvoseltamab Alone and Linvoseltamab with Carfilzomib Compared to Standard Treatment in Adults with Relapsed or Refractory Multiple Myeloma

Registered drugNo placebo

A Study of Linvoseltamab Alone and Linvoseltamab with Carfilzomib Compared to Standard Treatment in Adults with Relapsed or Refractory Multiple Myeloma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Aciclovir
Sponsor:Regeneron Pharmaceuticals Inc.

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Cerebral palsy

Not yet recruiting

Comparison of intrathecal baclofen pump and selective dorsal rhizotomy for children with cerebral palsy who cannot walk

Registered drugNo placebo

Comparison of intrathecal baclofen pump and selective dorsal rhizotomy for children with cerebral palsy who cannot walk

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Baclofen
Sponsor:UZ Leuven

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Acute lymphocytic leukaemia+6

Not yet recruiting

A Study Testing the Safety of CD19-Targeted CAR T-Cell Therapy in Children and Young Adults with Relapsed or Refractory B-Cell Cancers

InvestigationalNo placebo

A Study Testing the Safety of CD19-Targeted CAR T-Cell Therapy in Children and Young Adults with Relapsed or Refractory B-Cell Cancers

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:MB-HUCART19.1
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Type 1 diabetes mellitus+1

Not yet recruiting

A study testing dapagliflozin and SC0062 together compared to SC0062 alone in adults with type 1 diabetes and chronic kidney disease

Registered drugNo placebo

A study testing dapagliflozin and SC0062 together compared to SC0062 alone in adults with type 1 diabetes and chronic kidney disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Dapagliflozin
Sponsor:Universitair Medisch Centrum Groningen

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Hormone-dependent prostate cancer+1

Not yet recruiting

Study of Darolutamide to Increase PSMA Protein Expression in Patients with Hormone Sensitive Prostate Cancer

Registered drugNo placebo

Study of Darolutamide to Increase PSMA Protein Expression in Patients with Hormone Sensitive Prostate Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Darolutamide
Sponsor:Amsterdam UMC Stichting

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Lung neoplasm malignant

Not yet recruiting

Testing F-18-AraG imaging scan reliability in patients with lung cancer using repeat scans

Registered drugNo placebo

Testing F-18-AraG imaging scan reliability in patients with lung cancer using repeat scans

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Nelarabine
Sponsor:Amsterdam UMC Stichting

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Breast cancer

Not yet recruiting

Study of 6qc-ICG applied to the skin during breast cancer surgery to help surgeons see tumor edges in patients having breast conserving operations

Investigational

Study of 6qc-ICG applied to the skin during breast cancer surgery to help surgeons see tumor edges in patients having breast conserving operations

Investigational

The Netherlands

Participants:18–64 years · 65+ years · Healthy volunteers
Substances:6QC-ICG
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Acute lymphocytic leukaemia+2

Not yet recruiting

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo

The Netherlands

Participants:0–17 years
Substances:Blinatumomab
Sponsor:Amgen Inc.

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Cervix carcinoma

Not yet recruiting

A study of pembrolizumab and lenvatinib for patients with high risk locally advanced cervical cancer after chemoradiotherapy and brachytherapy

Registered drugNo placebo

A study of pembrolizumab and lenvatinib for patients with high risk locally advanced cervical cancer after chemoradiotherapy and brachytherapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Lenvatinib
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Angina pectoris

Not yet recruiting

A Study of Encoberminogene Rezmadenovec Gene Therapy for Patients with Refractory Angina Due to Coronary Artery Disease

InvestigationalNo placebo

A Study of Encoberminogene Rezmadenovec Gene Therapy for Patients with Refractory Angina Due to Coronary Artery Disease

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Flurpiradaz F 18
Sponsor:Xylocor Therapeutics Inc.

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Clinical research in Bilthoven

What the registry says about research in the country

01 Infectious Disease Prevention

Research focusing on optimizing vaccine effectiveness against multiple infectious diseases, including studies on meningococcal disease and influenza in different age groups.

Meningococcal Disease Prevention
Influenza Vaccination Timing
Early Measles Protection

Novel approaches include investigating optimal vaccination timing and early immunization strategies for enhanced protection.

02 Oncology Research

Advanced studies in breast cancer treatment, examining innovative therapeutic combinations for hormone receptor-positive cases.

Hormone Receptor Positive Breast Cancer
CDK 4/6 Inhibition Therapy
Sequential Treatment Strategies

Investigations focus on optimizing treatment sequences to improve progression-free survival rates.

03 Surgical Interventions

Clinical research examining surgical treatments combined with antibiotic therapy for improved patient outcomes.

Perianal Abscess Management
Combined Treatment Approaches
Fistula Prevention

Studies aim to enhance surgical outcomes through innovative combination therapies.

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