Clinical trials in Bilthoven – page 65

1 718 clinical trials in Bilthoven, The Netherlands across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Bilthoven at a glance

1 718

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1 718 trials in Bilthoven

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Efficacy and Safety of Clemastine Fumarate in Children and Adults with Pitt‑Hopkins Syndrome: A Randomized Placebo‑Controlled Trial

Not yet recruiting

Registered drug

Efficacy and Safety of Clemastine Fumarate in Children and Adults with Pitt‑Hopkins Syndrome: A Randomized Placebo‑Controlled Trial

Registered drug

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Clemastine Fumarate
Sponsor:Amsterdam UMC Stichting

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Non-small cell lung cancer

Not yet recruiting

A study to evaluate the safety and effectiveness of petosemtamab and pembrolizumab in adults with non-small cell lung cancer

Registered drugNo placebo

A study to evaluate the safety and effectiveness of petosemtamab and pembrolizumab in adults with non-small cell lung cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Pembrolizumab
Sponsor:Merus B.V.

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Hormone-refractory prostate cancer

Not yet recruiting

Comparison of standard dosing and blood level monitoring of abiraterone acetate for patients with metastatic castration-resistant prostate cancer

Registered drugNo placebo

Comparison of standard dosing and blood level monitoring of abiraterone acetate for patients with metastatic castration-resistant prostate cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abiraterone Acetate
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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A study to evaluate the safety and effectiveness of subcutaneous blinatumomab in adults and adolescents with relapsed, refractory, or minimal residual disease positive B-cell precursor acute lymphoblastic leukemia.

Registered drugNo placebo

A study to evaluate the safety and effectiveness of subcutaneous blinatumomab in adults and adolescents with relapsed, refractory, or minimal residual disease positive B-cell precursor acute lymphoblastic leukemia.

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Blinatumomab
Sponsor:Amgen Inc.

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Craniopharyngioma

Not yet recruiting

A study of tovorafenib for children and young adults with newly diagnosed or recurrent craniopharyngioma

InvestigationalNo placebo

A study of tovorafenib for children and young adults with newly diagnosed or recurrent craniopharyngioma

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Tovorafenib
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Lung neoplasm malignant

Not yet recruiting

Study of osimertinib and febuxostat to improve drug delivery in patients with EGFR-mutated non-small cell lung cancer without brain metastases

Registered drugNo placebo

Study of osimertinib and febuxostat to improve drug delivery in patients with EGFR-mutated non-small cell lung cancer without brain metastases

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Febuxostat
Sponsor:University Hospital Maastricht

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Malignant melanoma stage IV+1

Not yet recruiting

A study of ipilimumab and nivolumab to observe immune system changes in patients with unresectable stage III or IV melanoma

Registered drugNo placebo

A study of ipilimumab and nivolumab to observe immune system changes in patients with unresectable stage III or IV melanoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ipilimumab
Sponsor:Amsterdam UMC Stichting

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Cholelithiasis+2

Not yet recruiting

A study to evaluate if atorvastatin prevents gallstones in patients undergoing bariatric surgery

Registered drugNo placebo

A study to evaluate if atorvastatin prevents gallstones in patients undergoing bariatric surgery

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Atorvastatin
Sponsor:Spaarne Gasthuis Stichting

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Post-traumatic stress disorder

Not yet recruiting

A study to evaluate if hydrocortisone helps reduce symptoms of post-traumatic stress disorder in patients after exposure to a traumatic event.

Registered drug

A study to evaluate if hydrocortisone helps reduce symptoms of post-traumatic stress disorder in patients after exposure to a traumatic event.

Registered drug

The Netherlands

Participants:18–64 years · Healthy volunteers
Substances:Hydrocortisone
Sponsor:Amsterdam UMC Stichting

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Stomatitis

Not yet recruiting

Comparison of esketamine hydrochloride mouthwash and intravenous esketamine to reduce pain from oral mucositis in patients undergoing hematopoietic stem cell transplantation

Registered drugNo placebo

Comparison of esketamine hydrochloride mouthwash and intravenous esketamine to reduce pain from oral mucositis in patients undergoing hematopoietic stem cell transplantation

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Esketamine
Sponsor:Amsterdam UMC Stichting

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Pulmonary fibrosis

Not yet recruiting

A study to evaluate the effectiveness and safety of admilparant in patients with progressive pulmonary fibrosis

Investigational

A study to evaluate the effectiveness and safety of admilparant in patients with progressive pulmonary fibrosis

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Admilparant
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Endometrial cancer+7

Not yet recruiting

A study to evaluate the safety of SGN-ALPV in patients with advanced solid tumors

InvestigationalNo placebo

A study to evaluate the safety of SGN-ALPV in patients with advanced solid tumors

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:SGN-ALPV
Sponsor:Seagen Inc.

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Clinical research in Bilthoven

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01 Infectious Disease Prevention

Research focusing on optimizing vaccine effectiveness against multiple infectious diseases, including studies on meningococcal disease and influenza in different age groups.

Meningococcal Disease Prevention
Influenza Vaccination Timing
Early Measles Protection

Novel approaches include investigating optimal vaccination timing and early immunization strategies for enhanced protection.

02 Oncology Research

Advanced studies in breast cancer treatment, examining innovative therapeutic combinations for hormone receptor-positive cases.

Hormone Receptor Positive Breast Cancer
CDK 4/6 Inhibition Therapy
Sequential Treatment Strategies

Investigations focus on optimizing treatment sequences to improve progression-free survival rates.

03 Surgical Interventions

Clinical research examining surgical treatments combined with antibiotic therapy for improved patient outcomes.

Perianal Abscess Management
Combined Treatment Approaches
Fistula Prevention

Studies aim to enhance surgical outcomes through innovative combination therapies.

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