Cardiovascular Research

At Tergooiziekenhuizen in Hilversum, a major focus is cardiovascular disease research, including acute myocardial infarction, atherosclerotic cardiovascular disease, peripheral arterial disease, and refractory angina. These studies are mainly designed to test new treatments, reduce heart-related events, and improve long-term outcomes for people at high cardiovascular risk.

  • Studies on myocardial infarction and prevention of recurrent heart events
  • Research in atherosclerosis, lipoprotein(a), and vascular inflammation
  • Trials for coronary artery disease, angina, and peripheral arterial disease

The site also contributes to research on better cardiovascular risk reduction strategies and improved management for patients with complex heart and vessel disease.

Oncology and Hematology

The site has an extensive portfolio in oncology and hematology, with studies in non-small cell lung cancer, breast cancer, prostate cancer, colorectal cancer, renal cell carcinoma, multiple myeloma, and lymphoma. Much of this work is aimed at evaluating new cancer therapies, improving treatment effectiveness, and finding better ways to personalize care.

  • Research in lung cancer, including early-stage and advanced disease
  • Trials in breast cancer, triple-negative breast cancer, and hormone receptor-positive disease
  • Studies in prostate cancer, colorectal cancer, and other advanced solid tumors
  • Hematology research in CLL, DLBCL, multiple myeloma, and related blood cancers

Several trials also explore biomarker-guided treatment and more targeted cancer care, reflecting a strong interest in precision oncology at Tergooiziekenhuizen.

Kidney, Metabolic, and Endocrine Disorders

Another important area is kidney disease, type 2 diabetes, obesity, and thyroid disease. These trials are focused on slowing disease progression, improving symptoms, and lowering the risk of serious complications in patients with chronic metabolic and endocrine conditions.

  • Studies in chronic kidney disease and kidney-related cardiovascular risk
  • Research in type 2 diabetes and associated heart and kidney outcomes
  • Trials addressing hypothyroidism and persistent fatigue
  • Work on obesity and broader metabolic health

This research aims to improve daily quality of life while also preventing progression to more severe disease.

Women’s Health and Reproductive Medicine

The site also supports studies in women’s health and reproductive medicine, including polycystic ovary syndrome, placenta previa, and preterm birth. These trials are designed to improve pregnancy outcomes, support fertility care, and reduce complications for mothers and babies.

  • Research on preventing preterm birth in high-risk pregnancies
  • Studies in PCOS and fertility treatment strategies
  • Pregnancy-related research involving placenta previa

This area highlights a practical focus on safer, more effective care for women during pregnancy and reproductive treatment.

Infection, Critical Care, and Acute Conditions

Tergooiziekenhuizen is active in studies of sepsis, Staphylococcus aureus bacteremia, and other serious infections, as well as acute neurologic and surgical conditions such as chronic subdural hematoma. The main goal is to improve survival, shorten illness, and refine treatment decisions for hospitalized patients.

  • Trials in sepsis and intensive care treatment optimization
  • Research on bacteremia and safer antibiotic use
  • Studies for chronic subdural hematoma to reduce the need for surgery

These projects reflect a strong interest in better acute-care strategies for patients with complex and potentially life-threatening conditions.

Neurology, Psychiatry, and Patient-Reported Outcomes

The research portfolio also includes mental health and neurologic topics such as depression, treatment response in electroconvulsive therapy, and persistent symptoms that affect everyday functioning. These studies aim to improve treatment tolerability, predict response, and better understand quality of life outcomes.

  • Research on depression and severe mood disorders
  • Studies seeking to improve outcomes and reduce side effects of ECT
  • Work on quality of life and ongoing symptoms after illness

This field combines clinical care with research on how treatments affect patients beyond standard medical outcomes.