Replimune oncolytic immunotherapy products are experimental cancer treatments that use modified viruses to fight cancer. These products work by infecting and destroying cancer cells while also helping the body’s immune system recognize and attack the tumor. The virus is designed to multiply inside cancer cells, causing them to break apart, and at the same time, it releases signals that alert the immune system to join the fight against the cancer.

Metastatic Melanoma – Metastatic melanoma is an advanced stage of skin cancer that has spread from its original location to other parts of the body. It develops when melanoma cells break away from the primary tumor and travel through the bloodstream or lymphatic system to distant organs. Common sites of spread include the lungs, liver, brain, and bones. The disease represents the most serious form of melanoma because the cancer cells have gained the ability to invade other tissues. As the condition progresses, tumors may develop in multiple organs throughout the body. The spreading nature of this disease makes it significantly more challenging to manage than melanoma confined to the skin.

Hepatocellular Carcinoma – Hepatocellular carcinoma is the most common type of primary liver cancer that originates in the main cells of the liver called hepatocytes. This disease typically develops in people with chronic liver conditions such as cirrhosis or long-term hepatitis infections. The cancer begins as abnormal cell growth within the liver tissue and can form single or multiple tumors. As it progresses, the tumors may grow larger and spread to other parts of the liver. The disease can also extend beyond the liver to nearby blood vessels and lymph nodes. In advanced stages, cancer cells may travel to distant organs including the lungs and bones.

Melanoma – Melanoma is a type of skin cancer that develops in melanocytes, the cells responsible for producing skin pigment. It usually appears as an unusual mole or dark spot on the skin that changes in size, shape, or color over time. The disease can occur anywhere on the body but is most common in areas exposed to sunlight. If detected early while still confined to the outer layer of skin, the abnormal cells remain localized. Without intervention, melanoma cells can grow deeper into the skin layers and potentially spread to lymph nodes. In more advanced cases, the cancer may reach distant parts of the body through the bloodstream.