This clinical trial is focused on preventing infections caused by Group G and C Streptococcus during childbirth. These bacteria can be part of the natural flora found in the vaginal and rectal areas of some pregnant women. The study aims to evaluate the effectiveness of giving antibiotics during labor to prevent infections in both the mother and the newborn. The antibiotics being studied are Clindamycin and Benzylpenicillin, which are administered through an injection or infusion.
Participants in this study are pregnant women who have been found to carry Group G or C Streptococcus in their vaginal-rectal area during routine screening in late pregnancy. The study will compare the effects of the antibiotics with a placebo to determine their effectiveness in preventing infections. The main goal is to see if these antibiotics can reduce the risk of postpartum infections in mothers and any related complications in newborns.
The study will follow participants from the time of labor through the postpartum period, which is the time after childbirth. Researchers will monitor for any infections in the mother that require antibiotic treatment up to three months after delivery. They will also observe the health of the newborn, including any need for additional medical care. The study is expected to provide valuable information on the best ways to prevent infections during and after childbirth.



Finland