This clinical trial is focused on understanding how certain medications affect children’s experiences after undergoing general anesthesia. The study involves children who are between 7 and 18 years old and are scheduled for surgery that requires general anesthesia. The medications being studied include DEXMEDETOMIDINE EVER PHARMA, which is a solution used for infusion, and MIDAZOLAM VIATRIS, which is a solution for injection or infusion. Additionally, a placebo, which is a non-active substance, will be used for comparison. The purpose of the study is to assess how these medications, used as premedication, impact the children’s experience during the perioperative period, which is the time surrounding the surgery.
During the study, children will receive one of the medications or the placebo before their surgery. Researchers will then observe and record various aspects of the children’s experiences, such as their level of anxiety, any changes in heart rate or blood pressure, pain after the surgery, and how quickly they recover from anesthesia. The study will also look at whether the medications affect memory, behavior, and overall quality of life after the surgery. The main focus is on the children’s self-reported experiences 24 hours after the surgery or before they leave the hospital if they are outpatients.
The trial aims to provide valuable insights into how these medications can improve the surgical experience for children by reducing anxiety and other negative effects associated with surgery and anesthesia. By understanding these effects, healthcare providers can make better-informed decisions about premedication for children undergoing surgery, potentially leading to improved outcomes and comfort for young patients.



France