The clinical trial is focused on studying a type of kidney cancer known as Renal Cell Carcinoma (RCC). This trial is investigating whether treatment with a medication called Durvalumab, either alone or in combination with another medication called Tremelimumab, can help delay the return of cancer or increase life expectancy in patients who have had surgery to remove their kidney cancer and are at a higher risk of the cancer coming back. Durvalumab is also known by its code name, MEDI4736.
The purpose of the study is to compare these treatments with the current standard approach, which involves active monitoring after surgery. Patients participating in the trial will receive the medications through an infusion, which is a way of delivering the treatment directly into the bloodstream. The study will follow patients over a period to observe the effects of the treatments on the return of cancer and overall survival.
Throughout the study, some patients will receive the medications, while others may receive a placebo. The trial aims to provide valuable information on whether these treatments can offer better outcomes for patients with Renal Cell Carcinoma after surgery. Participants will be monitored regularly to assess their health and any changes in their condition.



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