Ticagrelor is a medication that helps prevent blood clots. It works by stopping platelets, which are small blood cells, from sticking together. This is important for patients who have had heart problems because it can help prevent further heart attacks or strokes. In this trial, ticagrelor is used alongside another medication to see if it can improve heart health after surgery.

Acetylsalicylic Acid (ASA), commonly known as aspirin, is a medication that reduces pain, fever, and inflammation. It also helps prevent blood clots by making the blood less sticky. In this trial, ASA is used alone or with ticagrelor to see how well it can prevent heart problems after surgery in patients who have had heart issues.

Coronary Artery Disease – This condition involves the narrowing or blockage of the coronary arteries, usually due to atherosclerosis, which is the buildup of cholesterol and fatty deposits on the artery walls. As the disease progresses, the reduced blood flow can lead to chest pain, known as angina, especially during physical activity or stress. Over time, the restricted blood flow may cause damage to the heart muscle, potentially leading to a heart attack. The disease can also result in other complications such as heart failure or arrhythmias. Symptoms may vary, and some individuals may not experience noticeable signs until the disease has significantly advanced. Regular monitoring and lifestyle changes are often necessary to manage the condition effectively.