Oncology and hematologic malignancies
Research activity spans pancreatic cancer, glioblastoma, non-small cell lung cancer, multiple myeloma, breast cancer, and a broad range of melanoma subtypes, including uveal melanoma with liver metastases and in-transit metastasis. The portfolio also includes acute myeloid leukemia in both adult and pediatric settings, along with pediatric cancer and biomarker-oriented targeted cancer treatment.
- Pancreatic adenocarcinoma
- Melanoma and uveal melanoma
- Glioblastoma
- Acute myeloid leukemia
- Multiple myeloma
Additional interest extends to somatostatin receptor positive tumours, metastatic disease, and surgical oncology contexts linked to hepatic resection and liver metastases.
Cardiovascular, renal, and perioperative medicine
Trials address myocardial infarction, myocardial ischemia, heart failure, Takotsubo syndrome, and coronary artery disease including left main stenosis and coronary artery bypass grafting. The sponsor also studies acute kidney injury after cardiac surgery, chronic active antibody-mediated rejection in kidney transplant recipients, and high-risk hyperkalemia in heart failure with reduced ejection fraction.
- Acute coronary syndromes
- Heart failure and cardiomyopathy
- Kidney transplantation
- Acute kidney injury
- Perioperative cardiovascular care
Related work includes antiplatelet therapy, beta blockers, ACE inhibitors, SGLT2 inhibitors, and renal function preservation in vulnerable surgical and intensive care populations.
Rheumatology, musculoskeletal disorders, and orthopedic infection
The sponsor’s rheumatology-linked research covers rheumatoid arthritis-associated interstitial lung disease, arthritis of the temporomandibular joint, and congenital myopathy. Additional studies focus on periprosthetic hip joint infection, periprosthetic knee joint infection, and pain management in musculoskeletal disease.
- Rheumatoid arthritis-associated interstitial lung disease
- Temporomandibular joint arthritis
- Congenital myopathy
- Periprosthetic joint infection
- Postoperative pain
There is also interest in immune-mediated and functional complications that affect mobility, pulmonary capacity, and recovery after orthopedic or inflammatory disease.
Maternal, neonatal, and reproductive health
Clinical research includes infertility, frozen embryo transfer, induction of labour, and preeclampsia. The sponsor also investigates preterm preeclampsia management, outpatient labour induction, and pregnancy-related outcomes in high-risk obstetric care.
- Infertility
- Preeclampsia
- Induction of labour
- Pregnancy care
- Neonatal and infant renal protection
Neonatal studies also address acute kidney injury after cardiac surgery and retinopathy of prematurity, reflecting interest in early-life complications requiring specialized hospital care.
Ophthalmology, neurology, infectious disease, and metabolic health
Research spans neovascular age-related macular degeneration, retinopathy of prematurity, and ocular melanoma. Neurological and immunological topics include neurodegenerative diseases, tick-borne encephalitis, and vaccine response after stem cell transplantation. Metabolic and respiratory work includes obesity, postoperative obesity, and obstructive sleep apnea.
- Age-related macular degeneration
- Neurodegenerative disease
- Tick-borne encephalitis
- Obesity and sleep apnea
- Post-transplant vaccination
Further activity includes diabetic foot ulcer care, obesity surgery recovery, and sexual health and psychiatric sexual disorders, broadening the sponsor’s clinical scope across multiple specialty areas.
