#1 Clinical Trials Search in Europe

Lu Ag09222

Clinical trials are studying Lu Ag09222 in adults with migraine who did not get enough help from earlier preventive treatments. The main goal is to check how well it works for migraine prevention and to gather safety and efficacy data in a Phase 2 study.

Table of Contents

Trial overview

The available study for Lu Ag09222 is a Phase 2 clinical trial in adults with migraine.[1] It is a study of prevention, which means the researchers want to see whether the treatment can help reduce migraines over time.[1]

The trial status is Authorised, and the study type is interventional, meaning researchers give a study treatment and then measure the results.[1]

Who can join the study

This trial is for adults with migraine who have not been helped by prior preventative treatments.[1] In simple terms, the study is looking at people whose earlier medicine did not control migraine well enough.[1]

The trial data do not list more detailed entry rules, so the main known target group is adults with migraine and a history of poor response to prevention treatment.[1]

What is being measured

The main outcome is the change from baseline in Monthly Migraine Diary during Weeks 1-12.[1] Baseline means the starting point before treatment begins, so the study is checking how much migraine patterns change after treatment starts.[1]

The brief summary says the study is designed to evaluate the efficacy of Lu Ag09222 for migraine prevention.[1] Efficacy means how well the treatment works for the condition being studied.[1]

Study design and treatment groups

The interventions listed are Lu Ag09222 given subcutaneously and a placebo that matches the study medicine.[1] Subcutaneous means given under the skin, and a placebo is a comparison treatment that does not contain the active study drug.[1]

This kind of design helps researchers compare the study treatment with a control group, so they can better judge whether changes are due to Lu Ag09222 and not just chance.[1]

Trial phase and size

The study is in Phase 2, which is an early-to-mid stage of testing where researchers look more closely at whether a treatment may work and continue to watch safety.[1] The planned enrollment is 1036 participants, which means the study aims to include 1,036 people.[1]

A study of this size can help researchers collect more reliable information about migraine prevention in the target population.[1]

Key patient terms

Preventative treatment means medicine taken to reduce how often migraines happen.[1] In this trial, participants are people who did not get enough help from earlier preventive treatment.[1]

Monthly Migraine Diary is the record used to track migraine changes during the study.[1] Weeks 1-12 is the time window used for the main result measure.[1]

Interventional means the study gives a treatment and measures what happens afterward.[1] Authorised means the trial has been approved to move forward.[1]

Trial ID Phase Condition studied Status Enrollment
NCT06323928 Phase 2 Migraine Authorised 1036

FAQ

  • What is Lu Ag09222 being studied for? Lu Ag09222 is being studied for migraine prevention. The trial is looking at whether it can reduce migraine frequency over time.
  • Who can take part in the trial? The trial is for adults with migraine who have not been helped by prior preventive treatments. This means people whose earlier medicine did not work well enough.
  • What phase is the trial? This is a Phase 2 trial. Phase 2 studies usually look more closely at whether a treatment works and continue to monitor safety.
  • How many people are planned for the study? The planned enrollment is 1,036 participants. Enrollment means the number of people the study hopes to include.
  • What outcome is the trial measuring? The main outcome is the change from baseline in the Monthly Migraine Diary during Weeks 1 to 12. Baseline means the starting point before treatment begins.

Ongoing Clinical Trials on Lu Ag09222

  • Study on Lu AG09222 for Preventing Migraines in Adults Unresponsive to Previous Treatments

    Not recruiting

    1
    Investigated drugs:
    Bulgaria Czechia Denmark France Germany Hungary +5

Glossary

  • Migraine: A type of headache disorder that can cause strong head pain and other symptoms. In this trial, it is the condition being studied.
  • Preventive treatment: Medicine taken to help stop migraines from happening or to reduce how often they occur.
  • Phase 2: A mid-stage clinical trial. It helps researchers learn more about whether a treatment works and continue checking safety.
  • Interventional study: A study in which researchers give a treatment and then measure what happens.
  • Placebo: A treatment that looks like the study medicine but does not contain the active study drug. It is used for comparison.
  • Subcutaneous: Given under the skin. This is a common way to give some study medicines.
  • Enrollment: The number of people planned or allowed to join a study.
  • Baseline: The starting point before treatment begins. Results are often compared with this starting point.
  • Monthly Migraine Diary: A record used in the study to track migraine changes over time.
  • Efficacy: How well a treatment works for the condition being studied.

References