after joining the study you will attend an initial visit where your weight, height, waist size, blood pressure, and blood samples are measured. these measurements establish a starting point for later comparisons.

the study staff will also review your medical history, current medicines, and any allergies to ensure the trial drugs are safe for you.

you will be given a pre‑filled injection device containing either cagrilintide semaglutide (the test medication) or semaglutide (the comparator medication). the exact dose is assigned by the study and is described as 0 mg in the study documentation.

the medication is delivered by subcutaneous injection, which means it is placed under the skin using a small needle.

you will inject the medication once each week, on the same day of the week, as instructed. the injection is given under the skin of the abdomen or thigh.

continue the weekly injections for the entire treatment period defined by the study protocol.

the study includes a reduced‑calorie diet plan that aims to lower your daily energy intake. you will receive written guidance on portion sizes and food choices.

you are also asked to increase physical activity, such as walking, cycling, or other moderate exercises, according to the schedule provided by the study team.

you will return to the clinic at scheduled intervals (typically every 4 to 8 weeks) for safety checks and progress monitoring.

during each visit the staff will record your weight measurement, waist circumference, and may draw blood for tests such as cholesterol, glucose, and other safety labs.

if you experience any discomfort, unusual symptoms, or health changes, you should inform the study staff promptly. these are called adverse events and are recorded to evaluate the safety of the medication.

at the end of the treatment period you will attend a final visit where all measurements taken at baseline are repeated.

the final data will be used to determine changes in body weight, body‑mass index, and other health indicators compared with the start of the study.