This study focuses on testing a medication called lecanemab (also known as BAN2401) in people with Early Alzheimer’s Disease. This condition includes both mild cognitive impairment due to Alzheimer’s disease and mild Alzheimer’s disease dementia, which causes gradual memory decline and difficulties with daily activities. The purpose is to determine if the medication can help slow down the progression of early-stage Alzheimer’s disease symptoms.
The study medication lecanemab is given through intravenous infusion, which means it is delivered directly into the bloodstream through a vein. Some participants will receive the actual medication while others will receive a placebo. The study consists of two parts: an 18-month main phase followed by an extension phase where all participants can receive the actual medication.
During the study, participants will receive regular infusions of either lecanemab or placebo. The maximum dose used in the study is 10 milligrams per kilogram of body weight. Participants will need to have a study partner who spends at least 8 hours per week with them to help monitor their condition throughout the study. The total duration of treatment may last up to 48 months, including both the main phase and extension phase of the study.



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