Region Oestergoetland
Linkoping, Sweden
Rare diseases
Investigational molecules
Locations
A plain-language summary of the goals, design and what participants do
This clinical trial is focused on studying the effects of fluid therapy during laparoscopic surgery, which is a type of surgery performed through small incisions with the help of a camera. The study will compare two different treatments: Ringer's solution, which is a mixture of electrolytes including sodium lactate solution, magnesium chloride hexahydrate, potassium chloride, sodium chloride, and calcium chloride dihydrate, and human albumin solution, a protein derived from human blood. These treatments are used to optimize plasma volume and maintain stable blood flow during surgery.
The purpose of the study is to understand how these fluids affect the body during surgery, especially when the abdomen is inflated with carbon dioxide, which is common in laparoscopic procedures. Participants will receive either Ringer's solution or human albumin solution through an intravenous infusion, which means the fluid is delivered directly into a vein. The study will observe changes in blood components like hemoglobin and albumin, as well as kidney function and fluid balance before and after surgery.
The trial aims to provide insights into the best fluid management practices during surgery to ensure patient safety and improve surgical outcomes. By comparing these two treatments, the study hopes to determine which fluid is more effective in maintaining the necessary blood volume and circulation during the surgical procedure. The findings could help guide future recommendations for fluid therapy in surgical settings.
The trial runs in 5 steps – from screening to follow-up. Each step says what happens and what the team monitors.
5 criteria
4 criteria
Tell us about your condition – we search every trial in Europe and connect you with the right site.
We usually reply within a few days
All sites with verified contact details – recruitment status may not be available; ask directly
Linkoping, Sweden
Where you can join this trial
Countries are shaded by recruitment status. Click a recruiting country to ask about joining there.
RecruitingJoining a clinical trial can seem overwhelming. We guide you step by step, so you know exactly what to expect and how we support you through the process.
is a protein solution used in this trial to help increase the volume of blood plasma. It is often used during surgery to maintain blood pressure and improve circulation by expanding the blood volume.
is a type of fluid that contains a mix of salts and water. It is used in this trial to help maintain the body's fluid balance during surgery. It helps to keep the blood pressure stable and supports the circulation of blood.
Albumin is administered intravenously and is used to optimize plasma volume and hemodynamics during surgery, particularly in fluid therapy combined with laparoscopic procedures. It is well-established in medical literature as a volume expander and is commonly used in clinical settings. The main therapeutic indication is to maintain blood volume and pressure during surgical procedures. At the molecular level, albumin works by increasing the oncotic pressure in the blood vessels, which helps retain fluid within the circulatory system. It is classified pharmacologically as a plasma volume expander.
Ringer's solution is administered intravenously and is used to maintain fluid balance and support hemodynamics during surgery, especially in combination with laparoscopic techniques. It is widely recognized in medical literature and practice as a balanced electrolyte solution. The primary therapeutic indication is to provide fluid replacement and maintain electrolyte balance during surgical procedures. Its mechanism of action involves supplying essential electrolytes and fluids to the body, helping to maintain normal cellular function. It is classified as a crystalloid solution.
sourced from the EU Clinical Trials Register and site verification
Want to learn more about this trial or check if you can participate?
Tell us about your condition – we search every trial in Europe and connect you with the right site.