MF59-adjuvanted influenza vaccine is a type of flu shot designed to help protect against the influenza virus. This vaccine contains an ingredient called MF59, which is an adjuvant. An adjuvant is a substance that helps boost the body’s immune response to the vaccine, making it more effective. This means that when you receive this vaccine, your body is better prepared to fight off the flu if you are exposed to the virus. This vaccine is specifically being tested in people aged 65 and older to see how well it works in preventing the flu.

Non-adjuvanted influenza vaccine is another type of flu shot that is being compared to the MF59-adjuvanted vaccine in this study. Unlike the MF59-adjuvanted vaccine, this one does not contain an adjuvant. It is a standard flu vaccine that aims to protect against the influenza virus by helping your body recognize and fight the virus if you come into contact with it. This vaccine is also being tested in people aged 65 and older to evaluate its effectiveness in preventing the flu.

Influenza – Influenza, commonly known as the flu, is a contagious respiratory illness caused by influenza viruses. It primarily affects the nose, throat, and sometimes the lungs. The disease typically begins suddenly and can include symptoms such as fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, and fatigue. Influenza can spread through droplets when an infected person coughs, sneezes, or talks. The virus can also be transmitted by touching surfaces or objects that have the virus on them and then touching the mouth, nose, or eyes. The progression of the disease can vary, with some individuals recovering in a few days, while others may experience more severe symptoms.