Based on the provided trial data, I cannot specifically identify any medications or therapies to list, as the source material only mentions “Investigational Therapy” in general terms without specifying particular medications. The trial appears to be studying unspecified targeted treatments based on tumor molecular alterations, but no specific drug names or therapies are provided in the source data.

If you have additional information about the specific medications or therapies used in this trial, please provide it, and I will format the descriptions according to the requirements.

Advanced Cancer – A condition where cancer cells have spread from their original location to other parts of the body. The cancer cells travel through the bloodstream or lymphatic system, forming new tumors in distant organs or tissues. This process, known as metastasis, makes the disease more complex as it affects multiple areas. Advanced cancer typically develops in stages, beginning as a localized tumor that gradually spreads beyond its initial site. The disease can affect various organs and body systems simultaneously, with different patterns of spread depending on the type of original cancer.

Metastatic Cancer – A stage of cancer where malignant cells have spread from the primary tumor to other locations in the body. The cancer cells break away from the original tumor and create new tumors (metastases) in other organs or tissues. These secondary tumors are the same type of cancer as the primary tumor, even though they are growing in a different part of the body. The spreading process can occur through blood vessels, lymph nodes, or by direct extension to nearby tissues.